Oral Lichen Planus

Presentation Slides

Chinese Medicine Research Hub

Meta-Analysis

Traditional Chinese Medicine-based biological extracts, especially echinacea and honey, significantly alleviate pain and improve symptoms in oral lichen planus patients.

2026 Frontiers in Cellular and Infection Microbiology Efficacy of traditional Chinese Medicine-based biological extracts in the treatment of oral lichen planus
Chen X, Wang L, Xu C, Gu C, He C, Sun L, Yu X

Chinese Medicine Research Hub

Meta-Analysis

Integrated traditional Chinese and Western medicine regimens significantly improve response rates, pain relief and erosion healing, with the combination of Kouyanqing granules and immunomodulators proving most effective.

2025 Medicine Efficacy and safety of traditional Chinese medicine combined with immunomodulators in treating erosive oral lichen planus: A network meta-analysis of randomized controlled trials
Li Y, Guo X, Deng L, Chen C, Lv F, Gao J, Zou X, Zhang L

Chinese Medicine Research Hub

Systematic Review

Natural remedies including specific ancient Traditional Chinese Medicine, Indian Ayurveda, and Japanese Kampo Medicine regimens have shown effectiveness against oral lichen planus, a cancer-related autoimmune disease.

2022 Journal of Ethnopharmacology Experimental and clinical trial investigations of phyto-extracts, phyto-chemicals and phyto-formulations against oral lichen planus: A systematic review
Sahoo A, Jena AK, Panda M

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Oral Lichen Planus" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Oral Lichen Planus" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Oral Lichen Planus" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Meta-Analysis published in 2026 in the journal Frontiers in Cellular and Infection Microbiology found that Traditional Chinese Medicine-based biological extracts, especially echinacea and honey, significantly alleviate pain and improve symptoms in oral lichen planus patients. The researchers conducted a systematic search across PubMed, Embase, and Web of Science to identify randomized controlled trials analyzing the effectiveness of TCM-based biological extracts on oral lichen planus. A network meta-analysis was subsequently performed on selected trials, with the extracts' effectiveness ranked based on their Surface Under the Cumulative Ranking (SUCRA) scores. In the findings, 22 articles met the criteria and were included in the meta-analysis. Direct comparisons showed that the TCM-based biological extracts had a significant impact on reducing patients' pain, as reflected in the visual analog scale (VAS) scores. Furthermore, the network meta-analysis revealed that specific extracts like chamomile, curcumin, echinacea, and honey were particularly beneficial in lowering the patients' clinical scores. More specifically, chamomile, echinacea, and honey were potent in managing the VAS scores, reflecting their role in pain relief.

A Meta-Analysis published in 2025 in the journal Medicine found that Integrated traditional Chinese and Western medicine regimens significantly improve response rates, pain relief and erosion healing, with the combination of Kouyanqing granules and immunomodulators proving most effective. The methodology of this study involved a systematic evaluation and network meta-analysis of 21 randomized controlled trials involving 1762 patients suffering from erosive oral lichen planus. These trials were derived from nine primary electronic databases. The efficacy and safety of various Chinese herbal medicines combined with immunomodulatory therapies were analyzed using a random-effects model. Surface under the cumulative ranking curve was implemented to rank the comparative efficacy and clinical significance of the treatment regimens. The results reveal that the combination of Kouyanqing granules and immunomodulators showed the highest efficacy in response rate and pain relief. The Compound Danshen preparation and the Jiedu Yukou decoction with immunomodulators ranked second and third respectively in efficacy. The treatment demonstrating the lowest risk of recurrence was identified as total glucosides of peony, while Kangfuxin solution combined with immunomodulators exhibited the most significant improvement in erosion area. It was also noted that all treatment regimens were well-tolerated by patients with a minimal incidence of adverse effects.

A Systematic Review published in 2022 in the journal Journal of Ethnopharmacology found that Natural remedies including specific ancient Traditional Chinese Medicine, Indian Ayurveda, and Japanese Kampo Medicine regimens have shown effectiveness against oral lichen planus, a cancer-related autoimmune disease. The research analysed various studies concerning the effectiveness of ethnopharmacological treatments for oral lichen planus. These treatments were extracted from ancient regimens of Traditional Chinese Medicine, Indian Ayurveda, or Ayurvedic Medicine, and Japanese Kampo Medicine. Specifically, the team sought out information on the use of crude extracts, individual phytochemicals, and phyto-formulations and their impact on reducing the severity and pain associated with oral lichen planus. The sources of this information included in vivo, in vitro, and randomized controlled trial studies. The gathered results included a range of crude phytoextracts, individual phytochemicals, and crude formulations, as well as specific herbal cocktails used in traditional Eastern medical practices. A comprehensive listing was developed consisting of the plant species, the parts used, the phytochemicals they contain, and duration of treatment. In summary, it was found that these evidence-based, traditional remedies offer a promising cost-effective and less toxic alternative to steroids commonly prescribed for oral lichen planus management.

Moderation Tools

Topic