A review of the ethnopharmacology, phytochemistry and pharmacology of Notopterygium incisum
Azietaku JT, Ma H, Yu X, Li J, Oppong MB, Cao J, An M, Chang Y · Journal of Ethnopharmacology · 2017 April
DOI 10.1016/j.jep.2017.03.022
Objective
Notopterygium incisum Ting ex H.T. Chang, known in Chinese as ‘Qianghuo’ is a traditional Chinese medicinal herb with the rhizome and roots associated with meridians of the kidney and urinary bladder. This systematic review focuses on the ethnopharmacological uses of this herb, including recent advances on the phytochemical and pharmacological study of N. incisum. Recent analytical methods developed for the quantitative and qualitative determination of constituents in this herb have also been reviewed. Additionally, future trends and prospects in the study of this herb have been proposed.
Conclusions
In this paper, we have reviewed various researches conducted on N. incisum especially in areas of its ethnopharmacological use, phytochemicals, pharmacology and developed analytical methods. This herb has been used over the years in treating headache, rheumatoid arthritis, cold, diaphoretic etc, prompting many types of research into identifying which compounds are responsible for these activities and their mechanism of action. More research is needed in the area of pharmacokinetics and toxicology to give further information on the clinical use and control the quality of the herb.
Critical Appraisal
Published research can offer valuable insights, but a paper’s conclusions may go beyond what its results support. Critical appraisal examines the methods, findings and limitations to clarify what can reasonably be concluded—and what remains uncertain.
This article has not yet been critically appraised by the Research Hub.
Learn more about Critical Appraisal
Related insights
- Yu Xing Cao, a traditional Asian medicine, demonstrates organ protection, immune regulation, and anti-tumour activity when analysed in modern research.
- Jujube seed extract has been found to primarily reduce anxiety by regulating the GABAergic and serotonergic synapse pathways, specifically modulating GABRA1, HTR1A, and HTR2A.
- The Chinese herbal formulation SHG may alleviate chronic pain and enhance the overall health of patients with rheumatoid arthritis and fibromyalgia.
- Traditional Chinese Medicine (TCM) decoctions as supplementary therapy for rheumatoid arthritis significantly enhance efficacy and are safe.
- Acupuncture, in conjunction with Chinese herbs, enhances the treatment of uterine fibroids over the use of Chinese herbs alone.
- Fructus Lycii and Salvia miltiorrhiza Bunge extract (FSE) shows potential as a clinical treatment for retinitis pigmentosa by inhibiting photoreceptor cell death following oxidative stress.
- The research unveils luteolin, quercetin, and kaempferol in RALRG as promising complementary components for RP treatment, with a key role in managing oxidative stress and PI3K/AKT signaling pathways.
- Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
