Extraction, structural-activity relationships, bioactivities, and application prospects of Pueraria lobata polysaccharides as ingredients for functional products: A review
Wang J, Dai G, Shang M, Wang Y, Xia C, Duan B, Xu L · International Journal of Biological Macromolecules · 2023 July
DOI 10.1016/j.ijbiomac.2023.125210
Objective
Pueraria lobata (Willd.) Ohwi is an important resource with dual functions in medicine and food since ancient times. Polysaccharides are the main bioactive component of P. lobata and have various bioactivities, such as antidiabetic, antioxidant, immunological activities, etc. Here, we reviewed recent progress in isolation, identification, pharmacological properties, and possible therapeutic mechanisms of PLPs to update awareness of these value-added natural polysaccharides.
Conclusions
It was found that PLPs possess various bioactivities, including antioxidation, antidiabetic, immunomodulatory, hypolipidemic, antibacterial activities, regulation of intestinal flora, etc. The linkage patterns of glycosidic bonds might influence the bioactivities of PLPs. Meanwhile, PLPs have great development prospects in the health food and medical industries due to their non-toxicity. These discoveries establish a solid foundation for expanding the application and investigations of PLPs.
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