Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
A Network Pharmacology Study on the Similarities and Differences in the Mechanisms of Zuo Gui Wan/You Gui Wan for the Treatment of Premature Ovarian Failure
2022 Oct 18 Combinatorial Chemistry & High Throughput Screening Shanshan Mei, Chaoqin Yu, Jie Ding, Wen Cheng
Network Pharmacology Chinese Herbal Formulas Premature ovarian failure (POF) Ovarian Insufficiency You Gui Wan Zuo Gui Wan Ovarian Function Women's Health Chinese Herbal MedicineThe Chinese medicine formulas Zuo Gui Wan and You Gui Wan have the potential to treat premature ovarian failure through different pharmacological pathways.
HPLC-MS/MS based comparative pharmacokinetics of 12 bioactive components in normal and osteoporosis rats after oral administration of You-Gui-Wan
2021 Dec 21 Journal of Separation Science Hua Yin, Yahong Wang, Ling Wang, Xue Bai, Jianhua Zhang
Thus, the optimized analytical method, along with the pharmacokinetic evaluation in the osteoporotic model may offer a more comprehensive understanding to elucidate the anti-osteoporosis mechanism of You-Gui-Wan. These findings may aid in developing a more effective treatment plan for osteoporosis.
Animal Study Chinese Herbal Formulas You Gui Wan Osteoporosis Chinese Herbal Medicine
An experimental research into the potential therapeutic effects of Anti-Osteoporosis Decoction and Yougui Pill on ovariectomy-induced osteoporosis
2019 Sep 15 American Journal of Translational Research Gu F, Jiang J, Wang S, Feng T, Zhou Y, Ma Y, et al.
In conclusion, Anti-Osteoporosis Decoction (AOD) and Yougui Pill (YGP) exert regulatory effects on osteoporosis in ovariectomized rats. They may be potential candidates for the therapy and cure of human osteoporosis.
Animal Study Chinese Herbal Formulas You Gui Wan Osteoporosis Chinese Herbal Medicine
Integrated Systems Pharmacology, Urinary Metabonomics, and Quantitative Real-Time PCR Analysis to Uncover Targets and Metabolic Pathways of the You-Gui Pill in Treating Kidney-Yang Deficiency Syndrome
2019 Jul 26 International Journal of Molecular Sciences Chen R, Wang J, Zhan R, Zhang L, Wang X
The mechanism of action mainly involved energy metabolism, oxidative stress, ammonia metabolism, amino acid metabolism, and fatty acid metabolism. In short, our study demonstrated that targets and metabolic pathways for the treatment of KYDS by YGP can be effectively found via combining with systems pharmacology and urinary metabonomics. In addition to this, common and specific targets and metabolic pathways of KYDS treated by YGP can be found effectively by integration with the analysis of different biological samples (e.g., serum, urine, feces, and tissue). It is; therefore, important that this laid the foundation for deeper mechanism research and drug-targeted therapy of KYDS in future.
Network Pharmacology Chinese Herbal Formulas Kidney-Yang Deficiency You Gui Wan Chinese Herbal Medicine
Effect of Zuogui pill and Yougui pill on osteoporosis: a randomized controlled trial
2018 Feb Journal of Traditional and Complementary Medicine Wenxiong L, Kuaiqiang Z, Zhu L, Li L, Yan C, Jichao Y, et al.
Zuogui pill or Yougui pill could improve bone mineral density (BMD), ease pain, relieve Kidney deficiency syndrome, improve the quality of life osteoporosis patients, inhibit bone conversion and regulate the coupling balance of bone formation and bone resorption.
Randomised Controlled Trial Chinese Herbal Formulas You Gui Wan Osteoporosis Chinese Herbal MedicineResearch insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
2022 Combinatorial Chemistry & High Throughput Screening
The Chinese medicine formulas Zuo Gui Wan and You Gui Wan have the potential to treat premature ovarian failure through different pharmacological pathways.
Network Pharmacology Chinese Herbal Formulas Premature ovarian failure (POF) Ovarian Insufficiency Zuo Gui Wan Ovarian Function
A Network Pharmacology Study on the Similarities and Differences in the Mechanisms of Zuo Gui Wan/You Gui Wan for the Treatment of Premature Ovarian Failure
Shanshan Mei, Chaoqin Yu, Jie Ding, Wen Cheng
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
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The Chinese medicine formulas Zuo Gui Wan and You Gui Wan have the potential to treat premature ovarian failure through different pharmacological pathways.
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