Acupuncture has the potential to treat gastrointestinal (GI) disorders by regulating GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis.
Although acupuncture has been used as an appropriate adjunctive treatment for GI dysfunction diseases, the underlying mechanisms have not been clearly understood. Currently, there are no systematic and comprehensive review articles that clarify the regulatory effect of acupuncture on GI function. In this review, we discuss the regulation on GI function through acupuncture from the perspectives of GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis. The results of studies in both humans and animals suggest that acupuncture has the potential to treat GI disorders by regulating GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis. In addition, the dual regulatory effects and the intensity-dependent nature of acupuncture on GI motility are discussed.