Objective
Danggui Buxue Tang (DBT) is composed of Astragali Radix and Angelicae Sinensis
Radix in a weight ratio of 5:1. The recipe of the decoction is simple, and DBT has been widely
used in the treatment of blood deficiency syndrome for more than 800 years in China. Studies
on its chemical constituents show that saponins, flavonoids, volatile oils, organic acids, and
polysaccharides are the main components of DBT. In this paper, we summarize the recent research
advances of DBT in terms of its components, pharmacological activities, and possible mechanisms
of action as well as provide suggestions for further research.
Conclusions
Based on TCM theory, DBT is mainly used to
treat fatigue, thirst, weakness, women’s menstrual
periods and postpartum fever, anemia, and other
blood deficiency syndromes. Modern pharmacological
experiments have demonstrated that DBT possesses
a wide range of biological activities, thus showing
remarkable medicinal value. The use of DBT can
provide more treatment options for diseases with
clinical manifestations such as hemocytopenia, DN,
nerve damage, cardiovascular and cerebrovascular
diseases, fibrosis, and cancer.
