Low-level laser therapy (LAT) significantly improves nocturnal enuresis (commonly known as bedwetting) in children, with red and infrared wavelengths being the most commonly used modalities.
The methodology involved an exhaustive systematic review that was done by searching international databases using keywords related to laser therapy and nocturnal enuresis. From these searches, only randomized controlled trials (RCTs) were chosen, specifically those that utilized any form of low-level laser therapy in treating nocturnal enuresis. A total of eleven studies that used laser acupuncture therapy were selected, with 927 participants involved in these trials. The Cochrane risk-of-bias tool and grading of recommendations assessment development and evaluation were used to appraise all the included studies—a meta-analysis was conducted, making use of full and partial response rate variables.
The results showed that treatments that involved laser acupuncture therapy showed significant improvement compared to control groups when full response rates were analyzed. However, there was no significant distinction between groups treated with LAT and those that underwent conventional medication therapy. Laser acupuncture therapy was most commonly applied using red and infrared wavelengths, and the most common sites were the lower abdomen and back acupoints.
