PTSD
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Also known as: Post Traumatic Stress Disorder
Related Topics
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor‐blinded, randomised controlled trial
2026 Jul 07 General Psychiatry Yang S, Mok WC, Cheung DST, Tiwari A, Cheng CPW, Chen H, et al.
Randomised Controlled Trial TEAS Electroacupuncture Acupuncture PTSD Insomnia DepressionThe addition of electroacupuncture and transcutaneous electrical acupoint stimulation can yield significantly improved mental health symptoms in women who have experienced domestic violence.

Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses
2026 Jun 28 Alpha Psychiatry Li Y, Feng Y, Wu Y, Kong Q, Zhang B, Liu Y, et al.
Systematic Review Meta-Analysis Scalp Acupuncture Acupuncture PTSDCertain brain regions are consistently involved in various mental disorders, suggesting potential new therapeutic targets for acupuncture and electrical brain stimulation techniques.

The Role of Non-Pharmacological Interventions in Attenuating Anxiety and Stress Symptoms in PTSD: A Systematic Review
2026 Mar 18 Current Neuropharmacology Wal A, Chellammal HSJ, Verma R, Vig H, Mishra S, Wal P, et al.
Systematic Review PTSD AnxietyNon-pharmacological treatments, particularly Mindfulness-Based Stress Reduction and Cognitive Behavioral Therapy, are found highly effective and preferable in treating Post-Traumatic Stress Disorder.

Predictors of PTSD Symptom Reduction in a Secondary Analysis of a Randomized Controlled Clinical Trial
2025 Dec 23 Journal of Clinical Medicine Smith TC, Smith B, Hsiao AF, Munoz A, Aden C, Lai-Trzebiatowski J, et al.
Clinical Study Randomised Controlled Trial PTSD
Acupuncture for Anxiety, Depression, and Sleep in Veterans with Combat-Related Posttraumatic Stress Disorder: A Randomized Controlled Trial
2025 May 15 Journal of Clinical Medicine Hsiao AF, Lai-Trzebiatowski J, Smith T, Calloway T, Aden C, Jovanovic T, et al.
Randomised Controlled Trial Veterans Acupuncture PTSD Anxiety Sleep DepressionResearch insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
2026 General Psychiatry
The addition of electroacupuncture and transcutaneous electrical acupoint stimulation can yield significantly improved mental health symptoms in women who have experienced domestic violence.
Randomised Controlled Trial TEAS Electroacupuncture Acupuncture Insomnia Depression
Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor‐blinded, randomised controlled trial
Yang S, Mok WC, Cheung DST, Tiwari A, Cheng CPW, Chen H, et al.
2026 Alpha Psychiatry
Certain brain regions are consistently involved in various mental disorders, suggesting potential new therapeutic targets for acupuncture and electrical brain stimulation techniques.
Systematic Review Scalp Acupuncture Acupuncture
Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses
Li Y, Feng Y, Wu Y, Kong Q, Zhang B, Liu Y, et al.
2026 Current Neuropharmacology
Non-pharmacological treatments, particularly Mindfulness-Based Stress Reduction and Cognitive Behavioral Therapy, are found highly effective and preferable in treating Post-Traumatic Stress Disorder.
Systematic Review Anxiety
The Role of Non-Pharmacological Interventions in Attenuating Anxiety and Stress Symptoms in PTSD: A Systematic Review
Wal A, Chellammal HSJ, Verma R, Vig H, Mishra S, Wal P, et al.
2024 Journal of Psychosocial Nursing and Mental Health Services
The combination of acupuncture and brief, telehealth-based therapy greatly diminishes post-traumatic stress disorder symptoms, depression, anxiety, and enhances trauma-related cognition.
Clinical Study Acupuncture Anxiety Depression
Effectiveness of Acupuncture and Brief Telehealth Intervention for Individuals With Posttraumatic Stress Disorder
Lu W, Chen Y, Gao N, Wang K, Srijeyanthan J, Beninato J, et al.
2024 Military Medicine
Sleep disorder symptoms, including sleep apnea and insomnia, significantly influence the outcomes of stress treatment among post-deployment military service members.
Randomised Controlled Trial Sleep
Associations Between Sleep Disorders and Treatment Response in Service Members With Post-traumatic Stress Symptoms: A Secondary Outcome Analysis
Abanes JJ, Raiciulescu S
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.

Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses
2026 Jun 28 Alpha Psychiatry Li Y, Feng Y, Wu Y, Kong Q, Zhang B, Liu Y, et al.
Systematic Review Meta-Analysis Scalp Acupuncture Acupuncture PTSDCertain brain regions are consistently involved in various mental disorders, suggesting potential new therapeutic targets for acupuncture and electrical brain stimulation techniques.

The Role of Non-Pharmacological Interventions in Attenuating Anxiety and Stress Symptoms in PTSD: A Systematic Review
2026 Mar 18 Current Neuropharmacology Wal A, Chellammal HSJ, Verma R, Vig H, Mishra S, Wal P, et al.
Systematic Review PTSD AnxietyNon-pharmacological treatments, particularly Mindfulness-Based Stress Reduction and Cognitive Behavioral Therapy, are found highly effective and preferable in treating Post-Traumatic Stress Disorder.

Efficacy and underlying mechanisms of acupuncture therapy for PTSD: evidence from animal and clinical studies
2023 May 02 Frontiers in Behavioral Neuroscience Tang X, Lin S, Fang D, Lin B, Yao L, Wang L, et al.
In conclusion, many studies have confirmed that acupuncture could improve many symptoms in patients with PTSD by meta-analysis. Acupuncture's effect on PTSD may be mediated by the promotion of neuroprotection, neurogenesis, and synaptic plasticity in multiple brain areas, the regulation of stress responses in the neuroendocrine system, and signaling pathway involvement. This finding indicates that acupuncture has promising potential for treating PTSD.
Review Article Acupuncture PTSD
A Review of Trauma Specific Treatments (TSTs) for Post-Traumatic Stress Disorder (PTSD)
2021 Oct 15 Clinical Social Work Journal Lee E, Faber J, Bowles K
The review identified thirty-four empirically supported treatments for PTSD, encompassing conventional therapies such as cognitive behavioral therapy (CBT), eye movement desensitization and reprocessing (EMDR), and dialectical behavioral therapy (DBT), as well as non-conventional approaches like yoga, acupuncture, and music therapy. Each treatment's content, targeted population, type of trauma, outcomes, strengths, and limitations were evaluated to assist clinicians in choosing appropriate interventions.
Review Article PTSD
Efficacy and Underlying Mechanism of Acupuncture in the Treatment of Posttraumatic Stress Disorder: A Systematic Review of Animal Studies
2021 Apr 08 Journal of Clinical Medicine Kwon CY, Lee B, Kim SH
In behavioral evaluation, acupuncture, including MA and EA, reduced anxiety and fear responses and weakened fear conditioning, improved sleep architecture, reduced depressive symptoms, and alleviated the disturbance of spatial learning and memory of the PTSD animal models.
Systematic Review Brain Health Memory Acupuncture PTSD AnxietyClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Combining electroacupuncture and transcutaneous electrical acupoint stimulation for psychiatric disorders in women victims of domestic violence: An assessor‐blinded, randomised controlled trial
2026 Jul 07 General Psychiatry Yang S, Mok WC, Cheung DST, Tiwari A, Cheng CPW, Chen H, et al.
Randomised Controlled Trial TEAS Electroacupuncture Acupuncture PTSD Insomnia DepressionThe addition of electroacupuncture and transcutaneous electrical acupoint stimulation can yield significantly improved mental health symptoms in women who have experienced domestic violence.

Predictors of PTSD Symptom Reduction in a Secondary Analysis of a Randomized Controlled Clinical Trial
2025 Dec 23 Journal of Clinical Medicine Smith TC, Smith B, Hsiao AF, Munoz A, Aden C, Lai-Trzebiatowski J, et al.
Clinical Study Randomised Controlled Trial PTSD
Acupuncture for Anxiety, Depression, and Sleep in Veterans with Combat-Related Posttraumatic Stress Disorder: A Randomized Controlled Trial
2025 May 15 Journal of Clinical Medicine Hsiao AF, Lai-Trzebiatowski J, Smith T, Calloway T, Aden C, Jovanovic T, et al.
Randomised Controlled Trial Veterans Acupuncture PTSD Anxiety Sleep DepressionAssociations Between Sleep Disorders and Treatment Response in Service Members With Post-traumatic Stress Symptoms: A Secondary Outcome Analysis
2024 Oct 15 Military Medicine Abanes JJ, Raiciulescu S
Randomised Controlled Trial PTSD SleepSleep disorder symptoms, including sleep apnea and insomnia, significantly influence the outcomes of stress treatment among post-deployment military service members.

An RCT of Effects of Telephone Care Management on Treatment Adherence and Clinical Outcomes Among Veterans With PTSD
2017 Feb Psychiatric Services Rosen CS, Azevedo KJ, Tiet QQ, Greene CJ, Wood AE, Calhoun P, et al.
Telephone care management (TCM) improved treatment attendance for PTSD patients but did not lead to significant improvements in clinical outcomes such as PTSD symptoms, depression, substance use, and quality of life. The effectiveness of outcomes appears contingent on the quality and type of treatments received by patients.
Randomised Controlled Trial PTSD DepressionStudy Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.

Acupuncture for combat post-traumatic stress disorder: trial development and methodological approach for a randomized controlled clinical trial
2021 Sep 06 Trials Hollifield M, Hsiao AF, Carrick K, Gory Munoz A, Calloway T, Cocozza K, et al.
The study results will be definitive because both clinical and biological outcomes will be assessed and correlated. Issues such as the number needed for recruitment and improvement, use of sham acupuncture, choice of biological measure, and future research need will be discussed.
Study Protocol PTSD
Efficacy and safety of acupuncture in treating post-traumatic stress disorder
2020 Jun 26 Medicine Ding N, Li L, Song K, Huang A, Zhang H
The review holds the purpose of providing extra relevant knowledge regarding the available option and clinical application to clinicians. Meanwhile, the resulting evidence of this review may contribute to essential information that can help health policy makers, practitioners, acupuncturists, and patients.
Study Protocol Acupuncture PTSDPresentation Slides

Randomised Controlled Trial
The addition of electroacupuncture and transcutaneous electrical acupoint stimulation can yield significantly improved mental health symptoms in women who have experienced domestic violence.
Yang S, Mok WC, Cheung DST, Tiwari A, Cheng CPW, Chen H, Qin Z, Chan MY, Hu X, Yu KC, Chan PY, Li W, Liu SN, Gu MQ, Yang X, Lee D, Sin SH, Zhang ZJ

Systematic Review
Certain brain regions are consistently involved in various mental disorders, suggesting potential new therapeutic targets for acupuncture and electrical brain stimulation techniques.
Li Y, Feng Y, Wu Y, Kong Q, Zhang B, Liu Y, Yu S, Liu J, Cao J, Jeong P, Cui F, Kong J

Systematic Review
Non-pharmacological treatments, particularly Mindfulness-Based Stress Reduction and Cognitive Behavioral Therapy, are found highly effective and preferable in treating Post-Traumatic Stress Disorder.
Wal A, Chellammal HSJ, Verma R, Vig H, Mishra S, Wal P, Kumar A, Ashesh AM, Gasmi A

Clinical Study
The combination of acupuncture and brief, telehealth-based therapy greatly diminishes post-traumatic stress disorder symptoms, depression, anxiety, and enhances trauma-related cognition.
Lu W, Chen Y, Gao N, Wang K, Srijeyanthan J, Beninato J, Oursler J, Lin KWR, Ben-Ari TZ, Ray S, Caldwell B

Randomised Controlled Trial
Sleep disorder symptoms, including sleep apnea and insomnia, significantly influence the outcomes of stress treatment among post-deployment military service members.
Abanes JJ, Raiciulescu S

Experimental Study
Anshen Dingzhi prescription, a traditional Chinese medicine, effectively treats breast cancer-related post-traumatic stress disorder, potentially by regulating TNF-α, IL-1β, and BDNF levels.
Zhang H, Zhu Y, Zhu G, Yang S

Animal Study
Acupuncture can alleviate PTSD-related depression and anxiety by boosting protein synthesis required for synaptic plasticity via the mTOR pathway in the hippocampus.
Oh JY, Kim YK, Kim SN, Lee B, Jang JH, Kwon S, Park HJ

Clinical Study
iRest Yoga Nidra combined with acupuncture significantly improves psychological health in veterans compared to using acupuncture alone.
Wheeler MS, Glass CR, Arnkoff DB, Sullivan P, Hull A

Systematic Review
There are potential clinical benefits of acupuncture on PTSD symptoms and functional status immediately post-intervention, as well as PTSD and depressive symptoms in the months following completion of acupuncture treatment.
Grant S, Colaiaco B, Motala A, Shanman R, Sorbero M, Hempel S

Randomised Controlled Trial
Improvement in post traumatic stress disorder severity was significantly greater among those receiving acupuncture than in those receiving usual PTSD care.
Engel CC, Cordova EH, Benedek DM, Liu X, Gore KL, Goertz C, et al.

Systematic Review
Evidence of effectiveness of acupuncture for PTSD is encouraging but not cogent. Acupuncture may be a relatively safe alternative for PTSD in contrast to SSRI, if long-term therapy is needed for treatment.
Young-Dae Kim, In Heo, Byung-Cheul Shin, Cindy Crawford, Hyung-Won Kang, Jung-Hwa Lim,
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for PTSD" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for PTSD" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for PTSD" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Randomised Controlled Trial published in 2026 in the journal General Psychiatry found that The addition of electroacupuncture and transcutaneous electrical acupoint stimulation can yield significantly improved mental health symptoms in women who have experienced domestic violence. The study was conducted as a randomised controlled trial in Hong Kong, China and involved 110 Chinese women who had undergone domestic violence and had major depressive disorder. The participants were separated into two groups, one receiving care as usual alone, and the other receiving care as usual supplemented with two electroacupuncture sessions and three transcutaneous electrical acupoint stimulation sessions per week for 12 weeks. Outcomes were measured using tools such as the Beck Depression Inventory-II, 17-item Hamilton Depression Rating Scale, 10-item Perceived Stress Scale, PTSD Check List-Civilian Version, Insomnia Severity Index, and the 12-item Short Form Survey for health-related quality of life. In the results, it was found that at the end of the 12 weeks, the group that received the supplementary stimulation treatments had a significantly greater reduction in their depression scores, perceived stress, PTSD symptoms, insomnia severity and improvement in quality of life, compared to the group that received care as usual. In addition, the group receiving the stimulation treatment also showed significantly higher rates of clinical response and remission at the end of the study. No serious adverse events were related to the treatments.
A Systematic Review published in 2026 in the journal Alpha Psychiatry found that Certain brain regions are consistently involved in various mental disorders, suggesting potential new therapeutic targets for acupuncture and electrical brain stimulation techniques. In the study, the researchers implemented Neurosynth Compose to conduct a wide-ranging, coordinate-based analysis in order to identify potential brain regions associated with nine mental disorders, including schizophrenia, bipolar disorder, and major depressive disorder, amongst others. The identified regions were then translated onto the scalp's surface and used to accurately define intervention points in alignment with standard acupoints and the EEG 10-20 system, bypassing the need for a direct brain access. The comprehensive analysis successfully outlined scalp intervention areas for all the disorders investigated. The results largely supported existing clinical procedures but also proposed previously undisclosed regions as potential therapeutic sites of interest. There were areas found relevant to specific conditions, but interestingly, they also discovered that the dorsolateral and ventrolateral prefrontal cortices, middle temporal gyrus, and inferior parietal lobule were applicable to multiple psychiatric conditions. The results from this research could significantly contribute to the refinement of treatment protocols for scalp acupuncture and brain stimulation as well as inspire the development of new therapeutic strategies in the field of psychiatry.
A Systematic Review published in 2026 in the journal Current Neuropharmacology found that Non-pharmacological treatments, particularly Mindfulness-Based Stress Reduction and Cognitive Behavioral Therapy, are found highly effective and preferable in treating Post-Traumatic Stress Disorder. The methodology for this review involved a comprehensive search of twelve databases yielding fifty-five relevant studies published between 2008 and 2025. These studies reported on numerous interventions for PTSD including Mindfulness-Based Stress Reduction (MBSR), Cognitive Behavioral Therapy (CBT), Eye Movement Desensitization and Reprocessing (EMDR), laughter therapy, acupuncture, dietary modifications, and yoga, all subjected to randomized controlled trials and meta-analyses for therapeutic effectiveness. The findings indicate that non-pharmacological therapies offer substantial benefits in managing PTSD, especially for those specifically sensitive to medicinal treatments. The most effective and consistent results were observed with MBSR and CBT, indicating the importance of cognitive restructuring and mindfulness. While dietary modifications, yoga, acupuncture, and laughter therapy all contributed to stress relief or emotional regulation, EMDR showed significant potency in processing traumatic memories without the need for verbalization. These methods foster resilience, self-control, and autonomy.
A Clinical Study published in 2024 in the journal Journal of Psychosocial Nursing and Mental Health Services found that The combination of acupuncture and brief, telehealth-based therapy greatly diminishes post-traumatic stress disorder symptoms, depression, anxiety, and enhances trauma-related cognition. The open-trial pilot study involved 27 participants with confirmed PTSD diagnoses. They completed eight sessions of acupuncture and three telehealth sessions of a short treatment program for PTSD termed as Brief Relaxation, Education, and Trauma Healing (BREATHE) prior to the ABT. The results displayed a significant reduction in PTSD symptoms, symptoms of depression, feelings of anxiety, and improvement in trauma-related cognition. The study underscores that acupuncture can play a critical role in mental health recovery, and when combined with a brief therapy delivered through telehealth like BREATHE, it can aid the recovery of individuals suffering from PTSD.
A Randomised Controlled Trial published in 2024 in the journal Military Medicine found that Sleep disorder symptoms, including sleep apnea and insomnia, significantly influence the outcomes of stress treatment among post-deployment military service members. In a two-arm, single-center, randomized controlled trial conducted in Okinawa, Japan, active duty service members from all military branches were examined for the impact of sleep disorders on stress treatment outcomes. Using the Global Sleep Assessment Questionnaire and the Post-traumatic Stress Disorder Checklist, researchers assessed the relationship between sleep disorders and post-traumatic stress symptoms (PSS). Participants' sleep disorder symptoms were evaluated prior to intervention. Results show a strong correlation between sleep disorder symptoms, including excessive daytime sleepiness, difficulty sleeping due to work conditions, involuntary movements during sleep, and feelings of anxiety or sadness, and PSS outcomes. The presence of these symptoms, together with factors such as demanding work schedules, possible sleep apnea, insomnia, anxiety, and depression, contributed significantly to the effectiveness of PSS treatment. These findings suggest that addressing sleep disorders could potentially enhance PSS treatment responses in service members.
A Experimental Study published in 2024 in the journal Integrative Cancer Therapies found that Anshen Dingzhi prescription, a traditional Chinese medicine, effectively treats breast cancer-related post-traumatic stress disorder, potentially by regulating TNF-α, IL-1β, and BDNF levels. The methodology employed for the investigation involved a 4-week-long clinical trial, where the efficacy and mechanism of action of Anshen Dingzhi prescription (ADP) on breast cancer-related post-traumatic stress disorder (BC-PTSD) was analyzed. Patients were split into two groups to compare the impact of different treatments on stress, sleep quality, depression, anxiety, and overall well-being scores. Also, the fluctuations of serum cortisol, tumor necrosis factor-alpha(TNF-α), interleukin-1 beta (IL-1β) levels, and brain-derived neurotrophic factor (BDNF) were noted. Part of the study included a network analysis and molecular docking to explore how ADP's blood components interacted with IL1B, TNF, and BDNF. Adverse effects and overall treatment efficacy between groups were also tracked. Results indicated that both groups saw improvements in post-traumatic stress disorder, depression and anxiety ratings, as well as sleep quality and overall wellness. However, the group treated with ADP saw greater improvements. This group also had reduced TNF-α, IL-1β, elevated BDNF levels, and a lower incident of adverse effects compared to the control group. The network analysis results reveal that ADP's blood components could potentially act on IL1B, TNF, and BDNF, providing a theoretical foundation for its mechanism of action.
A Animal Study published in 2018 in the journal Scientific Reports found that Acupuncture can alleviate PTSD-related depression and anxiety by boosting protein synthesis required for synaptic plasticity via the mTOR pathway in the hippocampus. The researchers conducted their study by observing a PTSD rat model that had been induced with a single prolonged stress (SPS). They administered acupuncture at HT8, a known acupuncture point, and gathered data on the ensuing behavioral changes using the forced swimming, elevated plus maze, and open field tests. They compared these results with those achieved using fluoxetine, a common antidepressant drug. They aimed to probe the underlying mechanisms by which acupuncture might work by studying its effect on protein translation in the mTOR signaling pathway and its subsequent enhancement of the activation of synaptic proteins such as PSD95, Syn1, and GluR1 in the hippocampus. The effects of acupuncture at HT8 point resulted in a significant alleviation in both depression and anxiety-like behaviors that had earlier been induced by SPS in the rat test subjects. This alleviation of symptoms was disrupted by the administration of rapamycin. These results are comparable to those brought about by the use of fluoxetine. The results further show that acupuncture aids in regulating protein translation in the mTOR signaling pathway, boosting the activation of synaptic proteins like PSD95, Syn1, and GluR1 in the hippocampus.
A Clinical Study published in 2017 in the journal Mindfulness found that iRest Yoga Nidra combined with acupuncture significantly improves psychological health in veterans compared to using acupuncture alone. The study employed iRest Yoga Nidra, a mindfulness approach that promotes relaxation and focused attention, along with acupuncture. Initially developed for military use, iRest was combined with acupuncture in this exploratory study to determine its effectiveness. Specifically, this was tested on veterans with a view to improving their psychological health. Throughout the study, the participants were exposed to principles such as non-judgment and observation of opposing feelings and emotions, along with the inclusion of these principles into their everyday life. The analysis of results showed that the combined therapy using iRest and acupuncture had a marked effect on psychological health. There were significant improvements in areas such as depression, psychological symptom severity, depression or tension as a result of pain, and the emotional interference with activities of daily life. Conversely, the group that had only undergone acupuncture treatment showed no significant benefits in these areas. Also significant was that the comfort shown by the treatment group was a moderate to high degree in contrast to the low comfort experienced by the group receiving only acupuncture. The overall treatment condition demonstrated considerable changes, with veterans reporting substantive decreases in the levels of mild, moderate, and severe depression. Additionally, it was indicated that the benefits of the combined treatment did not differ across factors such as age, gender, or race.
A Systematic Review published in 2017 in the journal Journal of Trauma & Dissociation found that There are potential clinical benefits of acupuncture on PTSD symptoms and functional status immediately post-intervention, as well as PTSD and depressive symptoms in the months following completion of acupuncture treatment. Overall, the results of this systematic review warrant caution in promoting acupuncture as an evidence-based treatment for adult patients with PTSD despite identified positive treatment effects. We have limited confidence in estimates indicating that needle acupuncture reduces PTSD and depressive symptoms at follow-up compared to passive controls, TAU, and active interventions, and we have very limited confidence in the estimates for PTSD symptoms at post-intervention and functional status. Moreover, no significant differences were observed between acupuncture and comparators for other outcomes, including no evidence for post-intervention or longer term improves on important psychological outcomes such as anxiety symptoms and sleep quality. Evidence from RCTs does suggest that acupuncture is relatively safe. Larger trials that minimize participant attrition would improve the quality of and confidence in effect estimates.
A Randomised Controlled Trial published in 2014 in the journal Medical Care found that Improvement in post traumatic stress disorder severity was significantly greater among those receiving acupuncture than in those receiving usual PTSD care. Mean improvement in PTSD severity was significantly greater among those receiving acupuncture than in those receiving usual PTSD care (PCLΔ=19.8±13.3 vs. 9.7±12.9, P<0.001; CAPSΔ=35.0±20.26 vs. 10.9±20.8, P<0.0001). Acupuncture was also associated with significantly greater improvements in depression, pain, and physical and mental health functioning. Pre-post effect-sizes for these outcomes were large and robust. Acupuncture was effective for reducing PTSD symptoms. Limitations included small sample size and inability to parse specific treatment mechanisms. Larger multisite trials with longer follow-up, comparisons to standard PTSD treatments, and assessments of treatment acceptability are needed. Acupuncture is a novel therapeutic option that may help to improve population reach of PTSD treatment.
A Systematic Review published in 2013 in the journal Evidence-Based Complementary and Alternative Medicine found that Evidence of effectiveness of acupuncture for PTSD is encouraging but not cogent. Acupuncture may be a relatively safe alternative for PTSD in contrast to SSRI, if long-term therapy is needed for treatment. This is the first systematic review and meta-analysis of prospective clinical trials on the effectiveness of acupuncture for treatment of PTSD. Only 4 RCTs and 2 UCTs met the inclusion criteria for this review. Our main finding of this review is that acupuncture is effective for PTSD based on one high-quality RCT and a meta-analysis. Acupuncture has positive effects in PTSD patients, although the evidence is still lacking as to its true efficacy for this condition.
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