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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Tetramethylpyrazine: An Active Ingredient of Chinese Herbal Medicine With Therapeutic Potential in Acute Kidney Injury and Renal Fibrosis
2022 Jan 25 Frontiers in Pharmacology Li J, Gong X
The study concludes that TMP may effectively prevent AKI by reducing oxidative stress injury, inhibiting inflammation, preventing apoptosis of intrinsic renal cells, and regulating autophagy. Additionally, TMP shows potential in impeding the progression of CKD through its anti-renal fibrosis effects.
Review Article Renal Fibrosis Tetramethylpyrazine Acute Kidney Injury Chuan Xiong
Molecular mechanism of Chuanxiong Rhizoma in treating coronary artery diseases
2021 Jul Chinese Herbal Medicines Yin B, Guo Y, Liu Y, Zhao Y, Huang S, Wei X, et al.
CR supplements large amounts of NO in cells and vessels to achieve relaxation via the NO3−–NO2−–NO pathway, thereby making up for the deficiency caused by the lack of NO after the l-arginine-NO pathway is suppressed. This study also supports the potential use of a traditional Chinese herb for future drug development.
Network Pharmacology Chuan Xiong Heart Disease
Mechanisms exploration of Angelicae Sinensis Radix and Ligusticum Chuanxiong Rhizoma herb-pair for liver fibrosis prevention based on network pharmacology and experimental pharmacologylogy
2021 Apr Chinese Journal of Natural Medicines WU JZ, LI YJ, HUANG GR, XU B, ZHOU F, LIU RP, et al.
Angelicae Sinensis Radix (Danggui) and Ligusticum Chuanxiong Rhizoma (Chuan Xiong) herb-pair (DC) prevents the development of liver fibrosis by inhibiting collagen deposition, decreasing inflammatory reactions and bile acid accumulation, which provides insights into the mechanisms of herb-pair in improving liver fibrosis.
Network Pharmacology Chuan XiongReview Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
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