Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
How to submit an article:
- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073 or just the DOI name: 10.1109/5.771073 into the field above and click submit.
- The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
Shen Qi Wan ameliorates nephritis in chronic kidney disease via AQP1 and DEFB1 regulation
2024 Jan Biomedicine & Pharmacotherapy Liu Y, Hong X, Liu L, Li X, Huang S, Luo Q, et al.
SQW demonstrated a reduction in renal collagen deposition, decreased serum inflammatory cytokine levels, and improved renal function in adenine-induced CKD mice and AQP1-/- mice. The potential therapeutic target β-defensin 1 (DEFB1) was identified, and SQW was found to alleviate inflammatory responses by fostering AQP1-mediated DEFB1 expression. The renal-protective effect of SQW was partly attenuated after AQP1 gene knockout, highlighting its potential as a novel strategy for CKD management.
Experimental Study Shen Qi Wan Multiple Mechanisms of Shenqi Pill in Treating Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Molecular Docking
2022 Jun 26 Evidence-Based Complementary and Alternative Medicine Tong X, Xu S, Zhai D
The study identified 15 anti-NAFLD bioactive ingredients in SQP, including quercetin, kaempferol, stigmasterol, diosgenin, and tetrahydroalstonine. Key target proteins against NAFLD were AKT1, TNF, MAPK8, IL-6, and VEGFA. The main pathways involved PI3K/Akt signaling, HIF-1 signaling, MAPK signaling, and TNF signaling. Molecular docking predicted binding of quercetin, kaempferol, stigmasterol, diosgenin, and tetrahydroalstonine with AKT1, TNF, and MAPK8, suggesting their potential role in SQP's anti-NAFLD effects.
Network Pharmacology Non-Alcoholic Fatty Liver Disease Shen Qi Wan
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Shen Qi Wan" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Shen Qi Wan" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Shen Qi Wan" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
