Tian Ma
Also known as: Gastrodia Elata
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities
2019 Jul 02 Molecules Zhu H, Liu C, Hou J, Long H, Wang B, Guo D, et al.
In summary, many new ideas and techniques have been developed for the study of polysaccharides in traditional Chinese medicine. However, the extraction, analysis, and derivatization of G. elata polysaccharides are still conducted using traditional methods. Consequently, G. elata polysaccharides have not been fully studied. There is still much room for deeper research. New extraction, analysis, and derivatization research methods should be applied to the study of G. elata polysaccharides to further discover its potential bioactivity, functions, and applications.
Review Article Tian Ma
Traditional Chinese herbal formula relieves snoring by modulating activities of upper airway related nerves in aged rats
2018 May Drug Design, Development and Therapy Chung KT, Hsu CH, Lin CL, Wang SE, Wu CH
We suggested that the B210 might be a potential herbal formula for snoring remission.
Animal Study Chinese Cinnamon Tian MaAnalytical Techniques and Pharmacokinetics of Gastrodia elata Blume and Its Constituents
2017 Jul 08 Molecules Wu J, Wu B, Tang C, Zhao J
Although G. elata has been used for thousands of years in China, the lack of standardization and safety and efficacy studies vastly restricts its utilization worldwide. Since ancient times, GAS and HBA have been widely considered to be the major bioactive constituents or metabolites of G. elata in vivo. With phytochemical studies, more constituents, such as parishins and hydroxybenzyl nucleosides, have been reported to exert a greater potential effect. However, there are still multiple complications that needs to be considered such as chemical properties and utilizing for the public before further application can occur.
Review Article Tian Ma
Gastrodia elata and epilepsy: Rationale and therapeutic potential
2016 Nov Phytomedicine Matias M, Silvestre S, Falcão A, Alves G
Due to its recognised therapeutic properties, G. elata has gained an increasing interest within the scientific community and, therefore, new medicinal preparations containing G. elata rhizome itself or its bioactive components are expected to be developed in the coming years. Moreover, specific phytochemical constituents isolated from G. elata may also be considered to integrate programs of discovery and development of new anticonvulsant drug candidates.
Review Article Epilepsy Tian Ma
Neuropharmacological Potential of Gastrodia elata Blume and Its Components
2015 Jan Evidence-Based Complementary and Alternative Medicine Jang JH, Son Y, Kang SS, Bae CS, Kim JC, Kim SH, et al.
In this review, we summarized the protective effects of GE against neurodegenerative disorders and proposed the underlying mechanisms of the neuropharmacological potential of GE and its components. In addition, we confirmed that administration of vanillin, an active component of GE, ameliorates TMT-induced seizures, which may be related to the reduced neuronal death and microglial activation. Therefore, this review encourages the identification of specific GE components for use in possible preventive or therapeutic strategies for various neurodegenerative disorders and may also be helpful for the development of new treatments for incurable disorders.
Review Article Tian MaReview Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities
2019 Jul 02 Molecules Zhu H, Liu C, Hou J, Long H, Wang B, Guo D, et al.
In summary, many new ideas and techniques have been developed for the study of polysaccharides in traditional Chinese medicine. However, the extraction, analysis, and derivatization of G. elata polysaccharides are still conducted using traditional methods. Consequently, G. elata polysaccharides have not been fully studied. There is still much room for deeper research. New extraction, analysis, and derivatization research methods should be applied to the study of G. elata polysaccharides to further discover its potential bioactivity, functions, and applications.
Review Article Tian MaAnalytical Techniques and Pharmacokinetics of Gastrodia elata Blume and Its Constituents
2017 Jul 08 Molecules Wu J, Wu B, Tang C, Zhao J
Although G. elata has been used for thousands of years in China, the lack of standardization and safety and efficacy studies vastly restricts its utilization worldwide. Since ancient times, GAS and HBA have been widely considered to be the major bioactive constituents or metabolites of G. elata in vivo. With phytochemical studies, more constituents, such as parishins and hydroxybenzyl nucleosides, have been reported to exert a greater potential effect. However, there are still multiple complications that needs to be considered such as chemical properties and utilizing for the public before further application can occur.
Review Article Tian MaGastrodia elata and epilepsy: Rationale and therapeutic potential
2016 Nov Phytomedicine Matias M, Silvestre S, Falcão A, Alves G
Due to its recognised therapeutic properties, G. elata has gained an increasing interest within the scientific community and, therefore, new medicinal preparations containing G. elata rhizome itself or its bioactive components are expected to be developed in the coming years. Moreover, specific phytochemical constituents isolated from G. elata may also be considered to integrate programs of discovery and development of new anticonvulsant drug candidates.
Review Article Epilepsy Tian MaNeuropharmacological Potential of Gastrodia elata Blume and Its Components
2015 Jan Evidence-Based Complementary and Alternative Medicine Jang JH, Son Y, Kang SS, Bae CS, Kim JC, Kim SH, et al.
In this review, we summarized the protective effects of GE against neurodegenerative disorders and proposed the underlying mechanisms of the neuropharmacological potential of GE and its components. In addition, we confirmed that administration of vanillin, an active component of GE, ameliorates TMT-induced seizures, which may be related to the reduced neuronal death and microglial activation. Therefore, this review encourages the identification of specific GE components for use in possible preventive or therapeutic strategies for various neurodegenerative disorders and may also be helpful for the development of new treatments for incurable disorders.
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