Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Chinese Medicine Research Hub
Randomised Controlled Trial
Soybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects.
2022 Nutrients Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms
Han AL, Lee HK, Chon HS, Pae HO, Kim MS, Shin YI, Kim S
Chinese Medicine Research Hub
Systematic Review
Isoflavones found in soybeans can reduce risks of certain cancers and alleviate menopause-related symptoms among women, such as vasomotor syndromes, spinal bone loss, and hypertension.
2021 International Journal of Molecular Sciences Utilization of Isoflavones in Soybeans for Women with Menopausal Syndrome: An Overview
Chen LR, Chen KH
Chinese Medicine Research Hub
Systematic Review
Combining Gua Sha therapy with Western medicine appears to offer significant improvements in perimenopausal symptom management.
2018 Complementary Therapies in Medicine Effects of Gua Sha therapy on perimenopausal syndrome: A systematic review and meta-analysis of randomized controlled trials
Qing Ren, Xinyu Yu, Fujiu Liao, Xiaofan Chen, Dongmei Yan, Heyun Nie, Jinju Fang, Meng Yang, Xu Zhou
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Menopausal Syndrome" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Menopausal Syndrome" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Menopausal Syndrome" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Randomised Controlled Trial published in 2022 in the journal Nutrients found that Soybean lettuce extract effectively reduces symptoms of menopause syndrome without notable side effects. The study targeted adult women suffering from menopausal syndrome with a Kupperman index of 15 or more. Participants were split into two groups – the experimental group and the placebo group. The research spanned over a four-week period and embraced a total of 39 participants (with one dropping out). Measurements of body mass index, waist circumference, and several cholesterol levels were taken before and after the study, but these didn't show any significant changes.
In the results discussion, the most notable finding was a significant reduction in the Kupperman index in the experimental group. They were given the natural nitric oxide-containing soybean lettuce extract. This decrease denotes the alleviation of menopausal symptoms, offering an effective, natural alternative to hormone therapy. Conversely, the placebo group didn't show any substantial change, reinforcing the efficacy of the soybean lettuce extract.
A Systematic Review published in 2021 in the journal International Journal of Molecular Sciences found that Isoflavones found in soybeans can reduce risks of certain cancers and alleviate menopause-related symptoms among women, such as vasomotor syndromes, spinal bone loss, and hypertension. The study overviewed soybeans' chemical composition and focused mainly on isoflavones. The research examined the processes of soybean preparation that includes cleaning, drying, crushing, and dehulling, and extraction methods to derive various soy products, particularly focusing on isoflavones - daidzein, genistein, and S-equol. Various soy products such as refined soy oil, soy lecithin, free fatty acids, glycerol, and soybean meal were discussed, along with the presence of the minor biological constituents in remaining components.
The study explored the relationship between isoflavone consumption and disease prevention, particularly in relation to heart disease, cancer incidence—of the breast, bladder, and endometrial and colorectal—and menopause-related symptoms. The therapeutic effects of isoflavones were studied in the context of vasomotor syndromes, spinal bone loss, hypertension regulation, depressive symptoms during pregnancy, and in vitro glycemic control. In contrast, it failed to find definitive effects of isoflavones on cognition improvement and urogenital symptoms. The inconsistencies in defining the ingredients, doses, study durations, and outcomes of isoflavone studies proved challenging for the research.
A Systematic Review published in 2018 in the journal Complementary Therapies in Medicine found that Combining Gua Sha therapy with Western medicine appears to offer significant improvements in perimenopausal symptom management. The study analyzed 6 RCTs, mostly of low methodological quality, and found that combining Gua Sha therapy with Western medicine demonstrated statistically significant improvements in the Kupperman Menopausal Index (KMI) Score and hormone levels (FSH, LH, and E2) compared to Western medicine therapy alone, suggesting potential effectiveness in managing perimenopausal symptoms. Additionally, Gua Sha therapy combined with Western medicine showed favorable effects on the MENQOL scale. However, further research is needed to determine optimal frequency and dosage of Gua Sha therapy for perimenopausal syndrome treatment.
This article refers to a possible mechanism of gua sha. "In transgenic mouse models, the occurrence of therapeutic petechiae following scraping therapy implicated the destruction of erythrocytes which in turn triggered molecular changes to stimulate the upregulation of stress-inducible heme oxygenase-1 (HO-1). As a well-known heat shock protein, HO-1 has anti-nociceptive, anti-inflammatory, and hepatoprotective effects." —Jinnan C 23 Apr 2022
Cant find full article — 28 Sep 2021