Fenugreek

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Chinese Medicine Research Hub

Systematic Review

Fenugreek supplementation improved lipid parameters in adults.

2021 Journal of Ethnopharmacology Effect of fenugreek supplementation on blood lipids and body weight: A systematic review and meta-analysis of randomized controlled trials
Askarpour M, Alami F, Campbell MS, Venkatakrishnan K, Hadi A, Ghaedi E.

Chinese Medicine Research Hub

Systematic Review

Fenugreek supplementation could be considered as an effective lipid-lowering medicinal plant.

2020 Phytotherapy Research Effect of fenugreek consumption on serum lipid profile: A systematic review and meta-analysis
Kiyan Heshmat-Ghahdarijani,Neda Mashayekhiasl,Atefeh Amerizadeh,Zahra Teimouri Jervekani,Masoumeh Sadeghi,

Chinese Medicine Research Hub

Systematic Review

Consumption of fenugreek significantly increased amount of the produced breast milk versus placebo.

2017 Phytotherapy Research Effectiveness of fenugreek as a galactagogue: A network meta-analysis
Khan TM, Wu DB, Dolzhenko AV

Chinese Medicine Research Hub

Review Article

Fenugreek can be beneficial as an adjunct in controlling high blood glucose and lipid levels in people with diabetes.

2017 Nutrition Today Fenugreek: Overview of Potential Health Benefits
Singletary, Keith W.

Chinese Medicine Research Hub

Meta-Analysis

Fenugreek has hypoglycaemic and total cholesterol-lowering efficacy.

2016 Journal of Ethnopharmacology Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis
Gong J, Fang K, Dong H, Wang D, Hu M, Lu F.

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Fenugreek" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Fenugreek" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Fenugreek" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Systematic Review published in 2021 in the journal Journal of Ethnopharmacology found that Fenugreek supplementation improved lipid parameters in adults. A meta-analysis of 12 RCTs (14 arms) with 560 participants suggested a significant decrease in plasma concentrations of total cholesterol, triglycerides, and low density lipoprotein cholesterol, as well as an increase in plasma high density lipoprotein cholesterol, while body weight and body mass index were not altered.

A Systematic Review published in 2020 in the journal Phytotherapy Research found that Fenugreek supplementation could be considered as an effective lipid-lowering medicinal plant. Pooled data of indicated a significant impact of fenugreek supplementation on lowering total cholesterol (TC), low-density lipoprotein (LDL), and triglyceride (TG) and increasing the high-density lipoprotein (HDL) level compared with the control group. There were no significant differences in TC, TG, and LDL between pre- and post-fenugreek studies in the noncontrolled studies however, the result of combination of four studies without control group showed a significant increase in mean HDL. The results of subgroup analysis showed that the fenugreek reduced the TG and LDL and increases HDL levels in diabetic subjects more effectively.

A Systematic Review published in 2017 in the journal Phytotherapy Research found that Consumption of fenugreek significantly increased amount of the produced breast milk versus placebo. The pairwise comparison revealed that fenugreek was effective as a galactagogue compared to placebo, control, and reference groups. However, the effect of fenugreek was substantially inferior to Coleus amboinicus Lour and palm date. The NMA using pairwise comparison demonstrated the effect of C. amboinicus and palm date in the stimulation of the breast milk production was comparable and superior to all comparators.

A Review Article published in 2017 in the journal Nutrition Today found that Fenugreek can be beneficial as an adjunct in controlling high blood glucose and lipid levels in people with diabetes. Taken together, the outcomes from human investigations suggest that fenugreek can be beneficial as an adjunct in controlling high blood glucose and lipid levels in people with diabetes. However, larger, adequately powered, randomized, placebo-controlled, double-blind trials examining multiple measures of carbohydrate and lipid metabolism and insulin homeostasis are needed.

A Meta-Analysis published in 2016 in the journal Journal of Ethnopharmacology found that Fenugreek has hypoglycaemic and total cholesterol-lowering efficacy. A total of 10 articles (12 studies) were included in the analysis. Pooled results showed fenugreek significantly decreased the levels of fasting blood glucose (FBG), postprandial 2 h blood glucose, HbA1c and total cholesterol. In spite of the reductive trends in the triglyceride or LDL-c levels and incremental trends of HDL-c, these results were not statistically significant or need further verification for fenugreek in the treatment of diabetes mellitus and prediabetes. Some studies were of low quality. No liver and kidney toxicity were found in all included studies, and the main side effects were gastrointestinal discomfort.

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