Xi Xin

Presentation Slides

Chinese Medicine Research Hub

Systematic Review

Combined Ma Huang Fu Zi Xi Xin decoction and Shen Mai injection treatment showed improved heart rate and symptoms in under 60s with bradyarrhythmia

2023 Evidence-Based Complementary and Alternative Medicine Efficacy Evaluation of the Mahuang-Fuzi-Xixin Decoction in Combination with Shenmai Injection for Bradyarrhythmia Treatment: A Systematic Review and Meta-Analysis
Zhang Z, Li Y, Yu T, Yan M, Li S

Chinese Medicine Research Hub

Systematic Review

HuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates.

2022 Evidence-Based Complementary and Alternative Medicine The Effectiveness and Safety of Huangqi Xixin Decoction for Cough Variant Asthma: A Systematic Review and Meta-Analysis
Wang C, Xia Q, Hu B, Jiang W, Zhang H

Chinese Medicine Research Hub

Network Pharmacology

Asthma severity can be notably reduced by Xi Xin essential oil, which decreases inflammation, immunoglobulins, and fibrotic mediators, while also alleviating airway obstruction.

2022 Pharmaceutics Exploring the Potential Effects and Mechanisms of Asarum sieboldii Radix Essential Oil for Treatment of Asthma
Han JM, Kim MH, Choi LY, Kim G, Yang WM

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Xi Xin" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Xi Xin" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Xi Xin" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Systematic Review published in 2023 in the journal Evidence-Based Complementary and Alternative Medicine found that Combined Ma Huang Fu Zi Xi Xin decoction and Shen Mai injection treatment showed improved heart rate and symptoms in under 60s with bradyarrhythmia Using Ma Huang Fu Zi Xi Xin decoction along with Shen Mai injection (SMI) treatment is better than just SMI treatment for patients under 60 with bradyarrhythmia. This combo improves heart rate and reduces symptoms, with no major side effects. The combination's effectiveness might come from shared heart-rate boosting components. However, there were differences in heart rate data due to varied ECG analysis.

A Systematic Review published in 2022 in the journal Evidence-Based Complementary and Alternative Medicine found that HuoXiang ZhengQi (HQXXD) may be a safe and effective treatment for Chronic Cough Variant Asthma (CVA), improving clinical efficacy and airway responsiveness while reducing recurrence rates. HuoXiang ZhengQi (HQXXD) for Chronic Cough Variant Asthma (CVA) was systematically evaluated. The HQXXD group showed significantly higher total effective rates of clinical efficacy and airway responsiveness compared to the control group, while the recurrence rate was lower. Adverse reactions were not reported in HQXXD treatment, indicating its safety for CVA patients.

A Network Pharmacology published in 2022 in the journal Pharmaceutics found that Asthma severity can be notably reduced by Xi Xin essential oil, which decreases inflammation, immunoglobulins, and fibrotic mediators, while also alleviating airway obstruction. AEO was administered via a nebulizer for three weeks ahead of exposing mice to ovalbumin (OVA), a protein commonly used to provoke an allergic reaction, and particulate matter (PM), common air pollutants. Co-treatment of AEO, OVA, and PM was carried out for four weeks. Additionally, A549 lung epithelial cells were exposed to PM to study the influence of AEO on lung-fibrosis-related factors. In our study, we found that AEO notably inhibited goblet cell accumulation, which led to a decrease in epithelial thickness. Collagen deposition in lung tissues, a common marker of airway remodeling, was significantly inhibited by AEO in asthmatic mice exposed to OVA and PM. AEO also lessened the influx of inflammatory cells into the bronchoalveolar lavage fluid, an indicator of respiratory inflammation. Similarly, the increases in serum IgE and IgG, immunoglobulins associated with allergic reactions, and cytokines in lung tissues were reduced by AEO. Moreover, AEO successfully managed the expression of key fibrotic mediators, particularly POSTN and TGF-β. All these indicators point to AEO's potential as a promising therapeutic treatment to alleviate asthma symptoms.

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