Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Chinese herbal medicine presents beneficial effects in controlling disease activity and lowering glucocorticoid dosage in systemic lupus erythematosus patients.
Systematic Review Chinese Herbal Medicine
An extensive search of seven electronic databases was conducted for all randomized controlled trials focusing on Chinese herbal medicine treating systemic lupus erythematosus. These trials could consist of Chinese herbal medicine used either independently or as an adjunct to conventional treatments, and trials up until August 16, 2020, were considered. Data was gathered with a particular focus on measurement outcomes such as the lupus disease activity index, traditional chinese medicine symptom scores, glucocorticoids dosage, main serological testing, and the occurrence of adverse events. The collected data was pooled and analyzed using Review Manager 5.3 software.
The compiled data was resulted from thirteen randomized controlled trials with a total of 856 participants. The analyzed data revealed that compared to placebos, Chinese herbal medicine showed significant indications of reducing the lupus disease activity index and traditional Chinese medicine symptom scores. It also underscored a lowered dosage of glucocorticoids, decreased erythrocyte sedimentation rate, and increased levels of serum complement C4. No significant differences were noticed between Chinese herbal medicine and placebos when considering adverse events.
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Traditional Chinese medical prescriptions showed a correlation with pattern diagnosis in the treatment of systemic lupus erythematosus.
Clinical Study Dan Shen
In the methodology, clinical data encompassing patterns and prescriptions from the electronic medical records of patients with lupus at a medical center were gathered and processed. A specific coding system, termed the B-code, was used to encode patterns and prescriptions, offering a platform for processing and statistical analysis. Nonlinear canonical correlation analysis was then performed to investigate the connection between the patterns and prescriptions.
Regarding the results, from the 261 valid patient visits collected, a total of 46 patterns and 193 prescriptions were encoded into 57 B-codes. Yin, Vacuity, Heat, and Dampness were the most frequently observed B-codes both in patterns and prescriptions. Anemarrhena, Phellodendron, and Rehmannia Pill, along with Miltiorrhizae Radix, were identified as the most frequently used formula and herb, respectively. The most effective variable sets correlating the patterns and prescriptions were Water-rheum, kidney, and stasis. This suggests a rationale for pattern differentiation and the principle of treatment for systemic lupus erythematosus.
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Presentation Slides
Chinese Medicine Research Hub
Systematic Review
Chinese herbal medicine presents beneficial effects in controlling disease activity and lowering glucocorticoid dosage in systemic lupus erythematosus patients.
2021 Chinese Journal of Integrative Medicine Chinese Herbal Medicine for Systemic Lupus Erythematosus: A Systematic Review and Meta-analysis of Randomized, Placebo-Controlled Trials
Wang Y, Han M, Pedigo CE, Xie Z, Wang W, Liu J
Chinese Medicine Research Hub
Clinical Study
Traditional Chinese medical prescriptions showed a correlation with pattern diagnosis in the treatment of systemic lupus erythematosus.
2014 Complementary Therapies in Medicine A novel model for exploring the correlation between patterns and prescriptions in clinical practice of traditional Chinese medicine for systemic lupus erythematosus
Liu CY, Wu WH, Huang TP, Lee TY, Chang HH
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Systemic Lupus Erythematosus" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Systemic Lupus Erythematosus" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Systemic Lupus Erythematosus" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Systematic Review published in 2021 in the journal Chinese Journal of Integrative Medicine found that Chinese herbal medicine presents beneficial effects in controlling disease activity and lowering glucocorticoid dosage in systemic lupus erythematosus patients. An extensive search of seven electronic databases was conducted for all randomized controlled trials focusing on Chinese herbal medicine treating systemic lupus erythematosus. These trials could consist of Chinese herbal medicine used either independently or as an adjunct to conventional treatments, and trials up until August 16, 2020, were considered. Data was gathered with a particular focus on measurement outcomes such as the lupus disease activity index, traditional chinese medicine symptom scores, glucocorticoids dosage, main serological testing, and the occurrence of adverse events. The collected data was pooled and analyzed using Review Manager 5.3 software.
The compiled data was resulted from thirteen randomized controlled trials with a total of 856 participants. The analyzed data revealed that compared to placebos, Chinese herbal medicine showed significant indications of reducing the lupus disease activity index and traditional Chinese medicine symptom scores. It also underscored a lowered dosage of glucocorticoids, decreased erythrocyte sedimentation rate, and increased levels of serum complement C4. No significant differences were noticed between Chinese herbal medicine and placebos when considering adverse events.
A Clinical Study published in 2014 in the journal Complementary Therapies in Medicine found that Traditional Chinese medical prescriptions showed a correlation with pattern diagnosis in the treatment of systemic lupus erythematosus. In the methodology, clinical data encompassing patterns and prescriptions from the electronic medical records of patients with lupus at a medical center were gathered and processed. A specific coding system, termed the B-code, was used to encode patterns and prescriptions, offering a platform for processing and statistical analysis. Nonlinear canonical correlation analysis was then performed to investigate the connection between the patterns and prescriptions.
Regarding the results, from the 261 valid patient visits collected, a total of 46 patterns and 193 prescriptions were encoded into 57 B-codes. Yin, Vacuity, Heat, and Dampness were the most frequently observed B-codes both in patterns and prescriptions. Anemarrhena, Phellodendron, and Rehmannia Pill, along with Miltiorrhizae Radix, were identified as the most frequently used formula and herb, respectively. The most effective variable sets correlating the patterns and prescriptions were Water-rheum, kidney, and stasis. This suggests a rationale for pattern differentiation and the principle of treatment for systemic lupus erythematosus.