Glaucoma

Presentation Slides

Chinese Medicine Research Hub

Traditional Chinese Medicines (TCM) could increase the survival rate of retinal ganglion cells, thereby playing an active role in treating glaucoma.

2023 Journal of Ethnopharmacology Review on potential effects of traditional Chinese medicine on glaucoma
Qi S, Zhang J, Zhu H, Wang Z, Li W

Chinese Medicine Research Hub

Review Article

Phytochemicals in carrots, particularly carotenoids, are effective at reducing eyesight degeneration and treating chronic eye defects due to their antioxidant and anti-inflammatory properties.

2021 SSRN Electronic Journal The Nutraceutical potential of Carrots carotenoids in Chronic Eyes Defects (CEDs): A Review
Taiwo EA, Abdulkareem TT, Fajemisin E

Chinese Medicine Research Hub

Clinical Study

Anthocyanin supplements improve vision health by relaxing ciliary muscles, regenerating rhodopsin, and enhancing retinal blood circulation.

2019 Molecules Therapeutic Effects of Anthocyanins for Vision and Eye Health
Nomi , Iwasaki-Kurashige , Matsumoto

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Glaucoma" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Glaucoma" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Glaucoma" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A published in 2023 in the journal Journal of Ethnopharmacology found that Traditional Chinese Medicines (TCM) could increase the survival rate of retinal ganglion cells, thereby playing an active role in treating glaucoma. Methodology: The research involved a comprehensive collection and collation of scientific articles from various databases about TCM and its application on glaucoma. The therapeutic effects of TCM, including their specific formulae, crude drugs, and active components, were analyzed based on existing experimental and clinical research. The GSE26299 database was also used for a bioinformatics analysis of glaucoma, employing the GEO database chip. Results: The traditional Chinese medicines exhibited positive effects in treating glaucoma by potentially improving the microcirculation, managing oxidative stress, and regulating the immune system, which in turn increased the survival rate of retinal ganglion cells. Furthermore, the bioinformatics analysis speculated the pathogenesis of glaucoma to be associated with multiple signaling pathways. The study concluded that TCM could alleviate and treat glaucoma through various methods, with the provision that the differentiation syndrome should be the basis for proposing suitable treatment options.

A Review Article published in 2021 in the journal SSRN Electronic Journal found that Phytochemicals in carrots, particularly carotenoids, are effective at reducing eyesight degeneration and treating chronic eye defects due to their antioxidant and anti-inflammatory properties. Throughout the review process, seventy original research and review articles were examined, all published between 2000 and 2020 across four major journal databases: Elsevier, PubMed, ResearchGate and Plos One. The focus of the search was directed by six keywords, centring on both in-vivo and in-vitro study results related to the topic of interest. Among the various findings, it was consistently revealed that carrots contain a multitude of bioactive compounds, notably carotenoids, which have been proven to be effective in halting and treating eye degenerations including Nyctalopia, Myopia, Cataracts, Age-related Macular Diseases and Glaucoma. Carotenoids have been found to work as potent antioxidants and anti-inflammatory agents, defending eyes against vision loss due to oxidative stress. Thus, the increased consumption of carrots can potentially serve as a natural therapeutic approach and enhancer of vision.

A Clinical Study published in 2019 in the journal Molecules found that Anthocyanin supplements improve vision health by relaxing ciliary muscles, regenerating rhodopsin, and enhancing retinal blood circulation. The methodology of this review involved studying the effects of Anthocyanin, a supplement popular for eye health. Despite the low bioavailability of Anthocyanin, the supplement is reported to appear in intact form and in various metabolites. The review observes how Anthocyanin crosses barriers within the blood to reach the ocular area. The study also performed an in vitro analysis to comprehend how Anthocyanin impacts the ciliary muscles of the eye, crucial in treating vision conditions like myopia and glaucoma. Findings of the review reveal that Anthocyanin also stimulates the reformation of rhodopsin in the rod outer segment of frogs. The compound further demonstrated how to control eye elongation in a model of chick myopia induced by a negative lens. Ultimately, the review consolidated multiple clinical studies that provide evidence for the improvement of dark adaptation and transient myopic shift following intake of Anthocyanin. The supplement notably improves retinal blood circulation among patients with normal tension glaucoma.

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