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2019 Frontiers in Nutrition
Theoretical Article Cardiovascular Disease Oats
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Presentation Slides
Chinese Medicine Research Hub
Theoretical Article
Consumption of oat β-glucan may lower cholesterol and risk of cardiovascular disease by altering gut bacteria and their effects on bile acid and cholesterol metabolism.
2019 Frontiers in Nutrition The Cholesterol-Lowering Effect of Oats and Oat Beta Glucan: Modes of Action and Potential Role of Bile Acids and the Microbiome
Joyce SA, Kamil A, Fleige L, Gahan CGM
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Beta Glucan" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Beta Glucan" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Beta Glucan" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Theoretical Article published in 2019 in the journal Frontiers in Nutrition found that Consumption of oat β-glucan may lower cholesterol and risk of cardiovascular disease by altering gut bacteria and their effects on bile acid and cholesterol metabolism. The research paper focused on studying the impact of oat β-glucan on cholesterol levels and cardiovascular disease risk. The methodology revolved around examining how consumption of oat β-glucan might change the gut microbiota, particularly bacterial species that influence bile acid metabolism and the production of short chain fatty acids. These factors are crucial regulators of cholesterol homeostasis in the host body. The research thus looked into the repercussions on bile acid metabolism, reverse cholesterol transport, short-chain fatty acid production, bacterial metabolism of cholesterol, and microbe-host signaling.
The researchers found that oat β-glucan appears to have a significant effect on both the host's cholesterol levels and the composition and functionality of their gut microbiota, which in turn impacts bile acid metabolism and cholesterol homeostasis. It creates a potentially beneficial scenario where intestinal cholesterol may be removed for excretion. The results suggest that the benefits attributed to oat β-glucan are multifaceted and likely involve the regulation of complex interactions between microbes and the host at the level of the gastrointestinal interface. These novel insights demonstrate an interesting relationship between diet, gut microbiota, and host cholesterol metabolism.
