Hops
Recent Insights
A combined treatment of soy and hop extract is a safe and effective alternative to traditional hormone replacement therapy for improving postmenopausal symptoms.
Hops Menopause Soybean
Hop extract, particularly its component 8-Prenylnaringenin (8-PN), demonstrates potential in alleviating symptoms common in menopause such as osteoporosis, vasomotoric disturbances, and sexual motivation.
Hops Hot Flushes Menopause
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Humulus lupulus L. a potential precursor to human health: High hops craft beer
2023 Mar Food Chemistry González-Salitre L, Guillermo González-Olivares L, Antobelli Basilio-Cortes U
Hops BeerThis article was submitted by Jinnan C. and is awaiting moderation..
Efficacy and Safety of a Standardized Soy and Hop Extract on Menopausal Symptoms: A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
2021 Nov 01 The Journal of Alternative and Complementary Medicine Kim HI, Kim MK, Lee I, Yun J, Kim EH, Seo SK
Randomised Controlled Trial Soybean Menopause HopsThis article was submitted by Jinnan C. and is awaiting moderation..
A combined treatment of soy and hop extract is a safe and effective alternative to traditional hormone replacement therapy for improving postmenopausal symptoms.
Hop Extracts and Hop Substances in Treatment of Menopausal Complaints
2013 Mar 19 Neuropediatrics Keiler A, Zierau O, Kretzschmar G
Hot Flushes Osteoporosis Hops MenopauseThis article was submitted by Jinnan C. and is awaiting moderation..
Hop extract, particularly its component 8-Prenylnaringenin (8-PN), demonstrates potential in alleviating symptoms common in menopause such as osteoporosis, vasomotoric disturbances, and sexual motivation.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
A combined treatment of soy and hop extract is a safe and effective alternative to traditional hormone replacement therapy for improving postmenopausal symptoms.
2021 The Journal of Alternative and Complementary Medicine Efficacy and Safety of a Standardized Soy and Hop Extract on Menopausal Symptoms: A 12-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Kim HI, Kim MK, Lee I, Yun J, Kim EH, Seo SK
Randomised Controlled Trial Menopause Soybean
In this double-blinded, randomized controlled trial, researchers administered a combination of soy and hop extract to 78 postmenopausal women with moderate to severe symptoms. Conducted in the gynecological outpatient clinic of a tertiary hospital, all subjects had modified Kupperman Menopausal Index (KMI) scores over 20. Participants either received the treatment or a placebo, as the researchers sought to evaluate their menopausal symptoms over the course of 12 weeks. The changes to their menopausal symptoms were tracked through self-reported KMI scores at multiple intervals. They also gauged measures such as the serum levels of bone metabolism markers, ultrasonographic parameters, hormone profiles, and safety assurances, amongst others.
In terms of test results, after undergoing the 12-week treatment, the group receiving the combined soy and hop extract saw more considerable improvements in their symptoms compared to the placebo group. They particularly noted notable enhancements in conditions like fatigue, paresthesia, arthralgia, and myalgia, palpitations, and vaginal dryness. Lowered increases in urine N-telopeptide, a biomarker for bone metabolism, were observed in treatment group participants aged 50 and older. Meanwhile, endometrial thickness and hormonal profiles did not display any significant shifts in either group. Importantly, throughout the trial, no harmful side effects or events arose, speaking to the safety of the treatment.
Hop extract, particularly its component 8-Prenylnaringenin (8-PN), demonstrates potential in alleviating symptoms common in menopause such as osteoporosis, vasomotoric disturbances, and sexual motivation.
2013 Neuropediatrics Hop Extracts and Hop Substances in Treatment of Menopausal Complaints Keiler A, Zierau O, Kretzschmar G
Hot Flushes Menopause Osteoporosis
The methodology of this research involved identifying the major constituents of hop extract, with a focus on 8-Prenylnaringenin (8-PN) due to its estrogenic qualities. Several in vivo studies were conducted to explore the potential of hop extract and 8-PN in mitigating climacteric symptoms. Clinical studies conducted have mainly centered around menopausal discomforts, still, these studies provided broad results.
In the discussion of the results, it was found that hop extract, and more prominently, 8-PN, show promise in alleviating menopausal symptoms such as osteoporosis, vasomotoric issues, and sexual desire. Although 8-PN primarily activates the estrogen receptor α and presents only slight uterotrophic attributes, it also brings about estrogenic effects on the mammary gland. The results indicate potential application of 8-PN and hop extract in alleviating symptoms commonly associated with menopause.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
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A combined treatment of soy and hop extract is a safe and effective alternative to traditional hormone replacement therapy for improving postmenopausal symptoms.
Hop extract, particularly its component 8-Prenylnaringenin (8-PN), demonstrates potential in alleviating symptoms common in menopause such as osteoporosis, vasomotoric disturbances, and sexual motivation.
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