Chai Hu Shu Gan San (a traditional Chinese Medicine) is a promising in treating depression, especially in post-stroke and postpartum cases.
Systematic Review Chai Hu Shu Gan San Post-Stroke Depression Postpartum Depression
The review assessed the efficacy of Chai Hu Shu Gan San, a traditional Chinese medicine, in treating depression. Out of 560 initial studies, 42 trials met inclusion criteria. These studies were conducted in China from 2006 to 2016, involving 3234 patients with depression. Chai Hu Shu Gan San demonstrated better efficacy compared to controls, especially in post-stroke and postpartum depression. However, the methodological quality of the included studies was assessed as low, with high risks of bias. While Chai Hu Shu Gan San showed promise, further rigorously designed randomized controlled trials are needed for a conclusive evaluation of its safety and efficacy in treating depression.
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