Insights & Discussion
Menthacarin, derived from peppermint and caraway oil, effectively reduces symptoms, offers a safe alternative to risky drugs like cisapride, and shows promise for managing stomach problems in primary care.
Menthacarin works well in reducing symptoms like pain and bloating. It is safe and could be an alternative to other drugs like cisapride, which can be risky. This herbal treatment seems useful for stomach problems in primary care, but more research is needed. In short, Menthacarin, made from peppermint and caraway oil, is a safe and effective option for stomach issues in primary care.
Discover Related Insights
Ginger, peppermint and caraway oil combination showed strong effectiveness in managing upper gastrointestinal complaints, with melatonin and marine alginate demonstrating moderate evidence.
2022 Nutrients Effectiveness of Nutritional Ingredients on Upper Gastrointestinal Conditions and Symptoms: A Narrative Review Schulz RM, Ahuja NK, Slavin JL
Review Article Alginate Caraway GERD
The methodology consisted of a literature review of the scientific studies pertaining to nutritional ingredients for upper gastrointestinal relief. The selection was based on recurring mentions within the literature and frequent appearance in consumer products. A predefined search for specific nutritional ingredients and terms related to upper GI health was conducted in five databases - Embase, Medline, Derwent drug file, ToXfile, and PubMed. A manual search was also undertaken for each ingredient to ensure comprehensive review.
The studies that gained inclusion encompassed 16 human clinical trials assessing nine different ingredients. The products investigated were divided into categories, including botanicals - with sub-categories of fiber and combinations, and non-botanical extracts. Several products demonstrated good potential, others showed promising but moderate results, while some had limited support from the scientific research.
A combination of peppermint oil and caraway oil is an effective and safe short-term treatment for functional dyspepsia.
2019 Evidence-Based Complementary and Alternative Medicine A Combination of Peppermint Oil and Caraway Oil for the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis Juanjuan Li, Lin Lv, Jiaqi Zhang, Lin Xu, Enjin Zeng, Zedan Zhang, et al.
Systematic Review Caraway Digestive Health Indigestion
It is the first attempt to generate RCT data of peppermint oil and caraway oil (POCO) for the treatment of functional dyspepsia. In this meta-analysis, we evaluated the efficacy and safety of POCO based on five RCTs with 578 patients. The results demonstrated that POCO can significantly improve global symptoms of FD, with an NNT of 3 when data from four studies were pooled. The positive and significant efficacy in terms of improvement in epigastric pain was also shown between the two studies. Moreover, the available data have found that the safety profile of POCO is similar to placebo.
The strength of our findings is that no significant heterogeneity was detected across the studies. Besides, study designs of the included trials were fairly similar and the duration of treatment was identical. We used rigorous methodology as follows and believe that the results reflect the best available current evidence. Firstly, our literature search was comprehensive including all RCTs regardless of publication type and language. Besides, we adopted the intention-to-treat analysis on all data to enhance the robustness of the results.