This article contains findings obtained from research on animals:
- The results from animal research studies should not be directly applied to humans and the results may not generalise to the human population.
- There may be significant differences between species in terms of physiology, physiology, and pharmacology, as well as differences in the way diseases and treatments are modelled in animals.
- Any conclusions drawn from animal research should be considered with caution and in the context of other types of research studies such as observational studies, clinical trials, and reviews of the literature.
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Acupuncture covering the depth ranges for BL18, BL20, and BL22 and their targeting of various tissues potentially alleviates sympathetic nerve issues and ischemia with assistance of the diaphragm.
2022 Medicine Anatomical structures and needling method of the back-shu points BL18, BL20, and BL22 related to gastrointestinal organs: A PRISMA-compliant systematic review of acupoints and exploratory mechanism analysis Cho Y, Han Y, Kim Y, Han S, Oh K, Chae H, et al.
Systematic Review Back-shu point Back-Shu Points Digestive Health
Review analyzed 115 articles on needling depth and angle for back-shu acupuncture points in GI diseases. Key findings include the depth range for BL18, BL20, and BL22 points, their targeting of muscles, nerves, and diaphragmatic tissues, and the potential for acupuncture to alleviate sympathetic nerve overexcitability and ischemia while emphasizing the diaphragm's role in digestive function.
Honey exhibits significant anti-Helicobacter pylori activity, with at least 10% concentration proving effective in inhibiting gastric and duodenal ulcers, highlighting its therapeutic potential.
2020 Sains Malaysiana In vitro Study of Anti-Helicobacter pylori Activity of Honey: A Systematic Review Adam Q, Annuar F, Alfizah H, Mohd Fahami NA
Systematic Review Gastritis H Pylori Honey
The research involved a comprehensive review of 53 articles from electronic databases such as Medline via Ovid Medline, Scopus, and ScienceDirect spanning from 2000 to 2018. Selection criteria focused on studies reporting honey's effects on H. pylori-induced gastric and duodenal ulcers. Nine chosen articles detailed the positive impact of honey, suggesting a minimum 10% concentration as effective against H. pylori. The review underscores the need for further exploration into honey's active components and molecular mechanisms.
The positive outcomes reported in selected studies support honey's potential in inhibiting H. pylori infections, emphasizing the need for further investigations to elucidate the active components and underlying molecular mechanisms. The review sets the stage for future research aiming to provide robust evidence for the use of honey in clinical settings.
Acupuncture on back-shu points of five zang, significantly improves both the physical and mental fatigue in chronic fatigue syndrome patients, along with enhancing their psychological status.
2018 World Journal of Acupuncture-Moxibustion Acupuncture on back-shu points of five zang for chronic fatigue syndrome: A randomized control trial CHEN S, LIU R, WU B, CHEN S, GUO F, XUE X, et al.
Randomised Controlled Trial Back-Shu Points Chronic Fatigue Syndrome
In this study, sixty patients divided into a treatment group and a control group. The treatment group received acupuncture on the back-shu points of five zang organs. Techniques used included perpendicular and oblique needling, lifting-thrusting, and twisting-twirling, each acupoint being attended for 10 seconds. In contrast, the control group received the treatment outward of these points without seeking deqi, a sensation linked to effective needling, and with no manipulation. Both groups received treatments twice a week, each lasting twenty minutes, and to a total of eight treatments.
The study's results showed that there was a higher effective treatment rate seen in the group who received acupuncture on back-shu points than the control group. Physical and mental fatigue scores, assessed using Fatigue Scale-14, were significantly reduced post-treatment in the treatment group. Moreover, the Symptom Check-List 90, used to measure the patient's psychological status, showed notable improvement in the treatment group, demonstrating that the acupuncture approach used in the treatment group improved not just physical and mental fatigue but also the patients' psychological state. While the treatment rendered a positive impact on the control group too, the outcome was more pronounced in the treatment group.
Coconut water and milk demonstrate protective effects against ulceration, reducing inflammation, promoting cell proliferation and supporting mucosal homeostasis.
2017 Tissue and Cell Gastroprotective and mucosa homeostatic activities of coconut milk and water on experimentally induced gastropathies in male wistar rats Ajeigbe KO, Owonikoko WM, Egbe V, Iquere I, Adeleye G
Experimental Study Coconut Milk Coconut Water Stomach Ulcer
The study was conducted in two phases using 45 male wistar rats divided into 9 groups. The first phase involved treatment of five groups with different substances: normal saline, 95% ethanol, coconut water, coconut milk, and Omeprazole. Ulceration was induced with 95% ethanol except in the saline-control group. The second phase involved four groups: a control group, an ulcer control group receiving acetic acid, a group receiving coconut milk and another receiving Omeprazole. Drug treatments were administered twice daily for 3-6 days post-ulcer induction. Afterwards, blood was collected for haemocytometry and gastric tissues were harvested for histological examinations.
In this study, both coconut water and milk, as well as Omeprazole, led to reduced ulcer scores and gastric lesion indices compared to the ulcer control groups. They also resulted in significantly lower white blood cell, neutrophil, and lymphocyte counts compared to the ulcer and overall control groups. Coconut milk, in particular, was associated with a significant reduction in C-reactive protein. The experimental treatments also led to reduced neutrophil infiltration and an increase in mucus cell density. Notably, the coconut milk group showed significantly higher expressions of EGFR and CD31, indicating catalysis of mucosa homeostasis through angiogenesis and mucosal cell proliferation.
Peptic ulcers may be prevented and cured by well-chewed food rich in vegetable fibers and fermented milk products, which increase protective salivary mucus and decrease damaging bile flow.
1978 Psychoneuroendocrinology New approaches to the pathogenesis of peptic ulcer based on the protective action of saliva with special reference to roughage, vegetable fibre and fermented milk products Malhotra SL
Stomach Ulcer
The research conducted a review of epidemiologic studies focusing on the variations of diet and eating patterns related to the prevalence of peptic ulcer disease across various communities. The effects of dietary patterns were assessed on saliva, gastric juice, and bile. The role of bile was specifically examined in the pathogenesis of peptic ulcer, with the argument that it, rather than hydrochloric acid, played a causal role. The role of saliva in preventing peptic ulcers was emphasized, particularly the protective nature of salivary mucus which is swallowed with food.
The study then suggested the types of diets that can help prevent peptic ulcers, including those rich in roughage, cellulose, vegetable fibers, and fermented milk products such as ghee and yogurt. The research posited this kind of diet can increase the amount of salivary mucus and consequently decrease the flow rate of harmful bile. The study also noted that these insights showed minor changes in diet, and a slower pace of consumption could lead to substantial health benefits.
Moving from dietary composition to eating behaviors, it was suggested that food should be well-masticated to ensure these beneficial digestive processes have an opportunity to occur. At the same time, the research made the case that specific dietary components, particularly short-chain fatty acids like those found in milk products, can retard gall bladder contraction, thereby reducing the amount of bile entering the duodenal lumen. This secondary action further contributes to the potential prevention of peptic ulcers.
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