This article contains findings obtained from research on animals:
- The results from animal research studies should not be directly applied to humans and the results may not generalise to the human population.
- There may be significant differences between species in terms of physiology, physiology, and pharmacology, as well as differences in the way diseases and treatments are modelled in animals.
- Any conclusions drawn from animal research should be considered with caution and in the context of other types of research studies such as observational studies, clinical trials, and reviews of the literature.
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Acupuncture covering the depth ranges for BL18, BL20, and BL22 and their targeting of various tissues potentially alleviates sympathetic nerve issues and ischemia with assistance of the diaphragm.
2022 Medicine Anatomical structures and needling method of the back-shu points BL18, BL20, and BL22 related to gastrointestinal organs: A PRISMA-compliant systematic review of acupoints and exploratory mechanism analysis Cho Y, Han Y, Kim Y, Han S, Oh K, Chae H, et al.
Systematic Review Back-shu point Back-Shu Points Digestive Health
Review analyzed 115 articles on needling depth and angle for back-shu acupuncture points in GI diseases. Key findings include the depth range for BL18, BL20, and BL22 points, their targeting of muscles, nerves, and diaphragmatic tissues, and the potential for acupuncture to alleviate sympathetic nerve overexcitability and ischemia while emphasizing the diaphragm's role in digestive function.
Vincentka natural mineral water reduces gastric damage and improves antioxidant capacity in an animal model of acute gastric ulcers.
2022 Physiological Research Mineral Water Vincentka and its Influence on Mucosal Ulcers BUDINSKAYA K, NÁDENÍČEK J, STRAČINA T, HENDRYCH M, PÍREK O, BARTÁKOVÁ A, et al.
Experimental Study Mineral Water Mucosal Ulcers Stomach Ulcer
This pilot study involved 16 male Wistar rats, divided into two groups: an experimental group and a control group, each with eight rats. The study was conducted in three phases: a 7-day handling phase, a 7-day phase where the experimental group received Vincentka mineral water and the control group received tap water, and a final phase of acute gastritis induction lasting one day. After 24 hours post-induction, the animals were sacrificed for analysis. Tissue samples from the stomach and duodenum, as well as blood samples, were examined using histological microscopy, immunohistochemical, and biochemical methods.
The histopathological analysis showed significantly less damage to the stomach lining in the experimental group compared to the control group. There were notable differences in blood plasma antioxidant capacity, oxidative stress parameters, and other biochemical values between the groups. These findings indicate that Vincentka mineral water positively affects the development and symptoms of acute gastric ulcers in this animal model, suggesting potential benefits for similar human conditions.
Honey exhibits significant anti-Helicobacter pylori activity, with at least 10% concentration proving effective in inhibiting gastric and duodenal ulcers, highlighting its therapeutic potential.
2020 Sains Malaysiana In vitro Study of Anti-Helicobacter pylori Activity of Honey: A Systematic Review Adam Q, Annuar F, Alfizah H, Mohd Fahami NA
Systematic Review Gastritis H Pylori Honey
The research involved a comprehensive review of 53 articles from electronic databases such as Medline via Ovid Medline, Scopus, and ScienceDirect spanning from 2000 to 2018. Selection criteria focused on studies reporting honey's effects on H. pylori-induced gastric and duodenal ulcers. Nine chosen articles detailed the positive impact of honey, suggesting a minimum 10% concentration as effective against H. pylori. The review underscores the need for further exploration into honey's active components and molecular mechanisms.
The positive outcomes reported in selected studies support honey's potential in inhibiting H. pylori infections, emphasizing the need for further investigations to elucidate the active components and underlying molecular mechanisms. The review sets the stage for future research aiming to provide robust evidence for the use of honey in clinical settings.
Ban Xia Xie Xin decoction has shown superior effectiveness and safety for treating chronic atrophic gastritis than patent medicine plus western medicine.
2020 PLOS One Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis Cao Y, Zheng Y, Niu J, Zhu C, Yang D, Rong F, et al.
Systematic Review Gastritis Stomach Ulcer
In an analysis of the clinical efficacy and safety of Banxia Xiexin decoction (BXD) for chronic atrophic gastritis (CAG) treatment, seven electronic databases, including Ovid, Embase, PubMed, Cochrane Library, and more, were used. The criteria for inclusion in the study were up until September 21, 2020. A Jadad scale coupled with Cochrane Collaboration's risk of bias tool evaluated methodological quality.
Out of the 1985 patients identified for analysis across 26 randomized controlled trials, it was found that BXD treatment provided more effective and safe results than Chinese patent medicine in conjunction with western medicine. Additionally, BXD was seen to improve symptom scores for stomach distending pain and belching. It was also observed that BXD effectively inhibited Helicobacter Pylori, improved HP-related inflammation, and alleviated the degree of glandular atrophy, intestinal metaplasia, and dysplasia of gastric mucosa. Despite the promising results, limitations were identified in relation to methodological quality and sample size across the studies.
Acupuncture on back-shu points of five zang, significantly improves both the physical and mental fatigue in chronic fatigue syndrome patients, along with enhancing their psychological status.
2018 World Journal of Acupuncture-Moxibustion Acupuncture on back-shu points of five zang for chronic fatigue syndrome: A randomized control trial CHEN S, LIU R, WU B, CHEN S, GUO F, XUE X, et al.
Randomised Controlled Trial Back-Shu Points Chronic Fatigue Syndrome
In this study, sixty patients divided into a treatment group and a control group. The treatment group received acupuncture on the back-shu points of five zang organs. Techniques used included perpendicular and oblique needling, lifting-thrusting, and twisting-twirling, each acupoint being attended for 10 seconds. In contrast, the control group received the treatment outward of these points without seeking deqi, a sensation linked to effective needling, and with no manipulation. Both groups received treatments twice a week, each lasting twenty minutes, and to a total of eight treatments.
The study's results showed that there was a higher effective treatment rate seen in the group who received acupuncture on back-shu points than the control group. Physical and mental fatigue scores, assessed using Fatigue Scale-14, were significantly reduced post-treatment in the treatment group. Moreover, the Symptom Check-List 90, used to measure the patient's psychological status, showed notable improvement in the treatment group, demonstrating that the acupuncture approach used in the treatment group improved not just physical and mental fatigue but also the patients' psychological state. While the treatment rendered a positive impact on the control group too, the outcome was more pronounced in the treatment group.
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