This article contains findings obtained from research on animals:
- The results from animal research studies should not be directly applied to humans and the results may not generalise to the human population.
- There may be significant differences between species in terms of physiology, physiology, and pharmacology, as well as differences in the way diseases and treatments are modelled in animals.
- Any conclusions drawn from animal research should be considered with caution and in the context of other types of research studies such as observational studies, clinical trials, and reviews of the literature.
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Avocado consumption correlates with a wider variety of healthier food choices, offering potential benefits for weight control strategies.
2023 PLOS One Identifying usual food choices with avocados in a clinical trial cohort of overweight and obese adults in Australia Guan VX, Neale EP, Probst YC
Clinical Study Obesity
The study created a comprehensive database of avocado-containing foods and drinks based on the AUSNUT 2011-13 food composition structure. The data pulled from four food-based clinical trials consisted of the usual food intake information from overweight and obese volunteers. The Apriori algorithm of association rules was employed as a two-step descriptive methodology to identify the associations between avocado consumption and choices of various foods at each mealtime using a nested hierarchical food group classification scheme.
The findings revealed 34 separate avocado and avocado-inclusive foods and beverages. Avocado intake was prevalent within the studied cohort, with more than half consuming avocados regularly. Avocados were invariably associated with other food groups in main meal occasions, and during breakfast, lunch, and dinner, 68 food items containing avocados were identified for avocado consumers. This avocado-specific database offers insights into the variety of foods and beverages that incorporate avocados, reflecting broad food choices among regular avocado consumers.
Green tea supplementation can significantly reduce body weight in women with polycystic ovary syndrome, hence potentially beneficial in its clinical management.
2022 Nutrition Research Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysis Colonetti L, Grande AJ, Toreti IR, Ceretta LB, da Rosa MI, Colonetti T
Meta-Analysis Body Weight Green Tea Obesity
The research carried out was a systematic review of randomized controlled trials that focused on women with polycystic ovary syndrome, examining the effects of green tea supplementation versus a placebo. Relevant studies were sourced from electronic databases such as MEDLINE via PubMed, EMBASE via Elsevier, Cochrane Library, LILACS via BVS, and Web of Science using specific terms related to the illness and green tea. Criteria for the evaluation included effects on body weight, fasting insulin, body mass index, body fat percentage, daily caloric intake, waist and hip circumference, and the waist/hip ratio.
Among the studies considered, there were a total of 169 women, with 85 allocated to the green tea group and 84 to the placebo group. It became apparent that there was a significant reduction in body weight for the group that received green tea supplementation. This leans towards the potential of green tea to be beneficial in the management of this syndrome.
Green tea extract could be considered a potential agent to attenuate PCOS complications mainly due to its effect on weight loss and glycemic levels.
2021 Reproductive Biology and Endocrinology A comprehensive insight into effects of green tea extract in polycystic ovary syndrome: a systematic review Maleki V, Taheri E, Varshosaz P, Tabrizi FPF, Moludi J, Jafari-Vayghan H, et al.
Systematic Review Obesity
Current evidence indicates that green tea extract (GTE) supplementation has potential beneficial effects on PCOS. Of 314 articles found in the search, four human studies and four animal studies were included. All studies in humans showed the effects of GTE on weight loss. GTE's effect on decreasing testosterone levels in humans and LH levels in animals were also reported. In addition, increases in FSH and progesterone levels in animal models were observed. Although GTE improved fasting blood sugar and insulin levels, the effect of GTE on inflammatory parameters, such as TNF-alpha and IL-6 and antioxidant status, was limited to animal studies.
Almond-based diets may be effective in promoting short-chain fatty acid-producing bacteria and lowering glycated haemoglobin and body mass index in patients with type 2 diabetes compared with control.
2021 Nutrients The Effects of Almonds on Gut Microbiota, Glycometabolism, and Inflammatory Markers in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials Ojo O, Wang XH, Ojo OO, Adegboye ARA
Systematic Review Almond Gut Microbiota HbA1C
The research was a systematic review and meta-analysis, conducted using the preferred reporting items for systematic review and meta-analysis methodology. Diverse databases, including the Health Sciences Research Databases via EBSCOhost, Google Scholar, EMBASE, and other article's reference lists, were thoroughly searched following the population, intervention, control, outcome, and study framework. The searches encompassed all relevant studies available from the inception of these databases until August 1, 2021.
Nine randomised studies were analysed, eight of which were used for the meta-analysis. Results revealed that diets rich in almonds foster the growth of gut bacteria that produce short-chain fatty acids. Additionally, the analysis demonstrated that such diets effectively reduce both glycated haemoglobin levels and body mass index in patients with type 2 diabetes. However, the effects of almonds were not significant concerning fasting blood glucose, 2-hour postprandial blood glucose, various inflammatory markers, and certain other indicators of diabetes. The biological mechanisms attributed to reductions in glycated haemoglobin and body mass index are thought to be related to the nutritional composition of almonds, namely their high fibre content and low glycaemic index.
Coffee consumption may contribute to the prevention of several inflammatory diseases and types of cancer, with reduced mortality risk deemed safe up to 400mg of caffeine per day.
2021 Critical Reviews in Food Science and Nutrition Coffee consumption, health benefits and side effects: a narrative review and update for dietitians and nutritionists Barrea L, Pugliese G, Frias-Toral E, El Ghoch M, Castellucci B, Chapela SP, et al.
Review Article Metabolic Syndrome Obesity Type 2 Diabetes
The methodology used in this scholarly review was based on an extensive literature review using the PubMed/Medline database. As the primary research tool, this database facilitated the authors' collation and analysis of relevant studies concerning the impact of coffee consumption on health outcomes. The focus was to determine both the positive and negative aspects of coffee consumption, with an additional aim of providing dosage recommendations. The data collated from these studies was then summarised and analysed through a narrative approach, making the findings more digestible and interpretable.
The findings suggested that coffee consumption may play a significant role in preventing inflammatory and oxidative stress-related diseases such as obesity, metabolic syndrome and type 2 diabetes. In addition, findings indicated that coffee consumption also seemed to have an association with a lower incidence of several types of cancer and a reduction in the risk of all-cause mortality. However, notable is the need for a time gap between coffee consumption and the intake of some drugs to avoid potential interactions. It was also concluded that the consumption of up to 400mg/day of caffeine was generally found to be safe for the average person.
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