• Sign In
Video Meeting

Join A Meeting

Select an available room to start a video meeting with other members of Ping Ming Health.


Meeting Room 1
Available

Telehealth Room 2
Available


PRIVACY NOTICE
By default, the video meeting room is not locked. Make sure you are aware of other participants who are in the room with you during your meeting.

Research Hub
Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study
Article DOI: https://doi.org/10.1080/09513590.2021.1991909
Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study
Article DOI: https://doi.org/10.1080/09513590.2021.1991909

Anaemia 10Autoimmune Disease 7Guillain-Barre Syndrome 2Multiple Sclerosis 9Systemic Lupus Erythematosus 4Bladder Conditions 9Benign Prostatic Hyperplasia 11Chronic Kidney Disease 27Overactive Bladder 6Prostatitis 2Urinary Incontinence 2Urinary Retention 1Urinary Tract Infection 5Cardiovascular Disease 67Angina 2Atherosclerosis 7Atrial Fibrillation 8Cardiac Arrhythmia 2Stroke 23Children's Health 54Bedwetting 1Precocious Puberty 1Chronic Fatigue Syndrome 9Chronic Pain 20Cluster Headache 1Headache & Migraine 20Peripheral Neuropathy 4Eye Health 5Age-Related Macular Degeneration 8Dry Eye 11Eye Fatigue 1Glaucoma 2Facial Conditions 11Bell's Palsy 4Temporomandibular Disorders 13Trigeminal Neuralgia 2Immunity 19Male Fertility 19Sperm Quality 15Neurodevelopmental Disorders 1ADHD 19Autism 11Neurological Disorders 6Alzheimer's Disease 29Dementia 5Parkinson's Disease 18Oral Health 4Gingivitis 2Periodontitis 4Plaque 1Postoperative Care 4Sexual Health 4Erectile Dysfunction 5Spinal Cord Injury 6Thyroid Disease 10Hashimoto Disease 5Hyperthyroidism 2Hypothyroidism 7Tinnitus 7Vertigo 2

Arthritis 8Back, Hip & Leg Pain 17Carpal Tunnel Syndrome 16De Quervains Tenosynovitis 3Fibromyalgia 8Foot Pain 1Ankle Pain 4Heel Pain 9Gout 10Uric Acid 9Knee Pain 2Knee Osteoarthritis 15Low Back Pain 7Lumbar Disc Herniation 2Neck Pain 1Neck, Shoulder, Arm & Wrist Pain 13Osteoarthritis 15Osteoporosis 54Restless Legs Syndrome 8Rheumatoid Arthritis 25Rotator Cuff Injury 3Sciatica 6Shoulder Pain 12Frozen Shoulder 9Sports Injuries 3Tennis Elbow 4

Amenorrhea 1Female Fertility 41Hysterectomy 1IVF 34Embryo Transfer 7Implantation Failure 2Menopause 39Hot Flushes 12Ovarian Function 6Ovarian Insufficiency 7PCOS 56Pelvic Pain 4Period Pain 48Adenomyosis 4Endometriosis 34Period Pain & Endometriosis 16Postpartum Care 4Breastfeeding 13Lactation 1Mastitis 2Postpartum Depression 7Pregnancy 30Gestational Diabetes 3Labour Induction 12Labour Pain 10Miscarriage 2Morning Sickness 6Pre-Eclampsia 1Premenstrual Syndrome 12Uterine Fibroids 7Vulvodynia 3

Constipation 27Diarrhoea 6Gallstones 8Gastritis 5GERD 11Gut Microbiota 56Haemorrhoids 5Indigestion 17Inflammatory Bowel Disease 12Crohn's Disease 8Ulcerative Colitis 26Irritable Bowel Syndrome 25Stomach Ulcer 13H Pylori 6

Anosmia 3Asthma 13Common Cold 5Common Cold, Flu & Viral Infections 9COPD 6COVID-19 54Hay Fever 35Influenza 10Obstructive Sleep Apnoea 2Snoring 2Pneumonia 3Sinusitis 8URTI 6

Acne 15Eczema 39Excessive Sweating 1Hives 5Itchy Skin 1Postherpetic Neuralgia 2Psoriasis 6Shingles 8Wound Healing 10

Cholesterol 45HDL-C 6LDL 15Triglyceride 16Fatty Liver Disease 17NAFLD 31High Blood Pressure 60Diastolic Blood Pressure 5Systolic Blood Pressure 3Obesity 56Type 2 Diabetes 68Blood Sugar 31Diabetic Neuropathy 4HbA1C 5Insulin Resistance 13

Anorexia 9Anxiety 41Bipolar Disorder 2Brain Health 11Cognitive Function 37Memory 12Depression 73Drug Addiction 1Insomnia 59PTSD 15Schizophrenia 4

Bowel Cancer 5Breast Cancer 33Cancer Fatigue 3Cancer Pain 2Cancer Treatment Support 22Cancer-Related Insomnia 2Cervical Cancer 6Cervical Dysplasia 2HPV 4Chemotherapy 15Chemotherapy-Induced Peripheral Neuropathy 6Colorectal Cancer 10Endometrial Cancer 4Liver Cancer 5Lung Cancer 5Melanoma 1Ovarian Cancer 3Pancreatic Cancer 1Prostate Cancer 14Stomach Cancer 11Urothelial Cancer 2

Acupressure 5Acupuncture 253Back-Shu Points 3Ear Acupuncture 23Electroacupuncture 26Group Acupuncture 5Laser Acupuncture 3Scalp Acupuncture 5Chinese Medicine Diet Therapy 5Cupping 15Gua Sha 7Meridian Massage 14Moxibustion 17Tai Chi & Qi Gong 4

Ai Ye 3An Gong Niu Huang Wan 1An Shen Ding Zhi decoction 2Ba Ji Tian 3Ba Zhen Tang 2Bai Hua She She Cao 1Bai Ma Gu 1Bai Zhi 1Bai Zhu 2Ban Xia 2Bu Fei Na Shen pill 1Bu Gu Zhi 1Bu Shen Huo Xue Hua Tan decoction 1Bu Shen Tian Jing Formula 2Bu Sheng Hui Yang Fang 1Bu Yang Huan Wu 2Bu Zhong Yi Qi Tang 5Chai Hu 4Chai Hu Jia Long Gu Mu Li Tang 2Chai Hu Shu Gan San 6Chan Tui 1Chuan Xin Lian 1Chuan Xiong 2Da Cheng Qi Tang 1Dan Dou Chi 2Dan Shen 10Dan Shen Decoction 1Dang Gui 8Dang Gui Bu Xue Tang 2Dang Gui Shao Yao San 4Dang Gui Si Ni Decoction 4Dang Shen 3Di Huang 2Dingji Fumai Decoction 1Du Huo 1Du Huo Ji Sheng Wan 3Du Zhong 8Er Xian Decoction 1Er Zhi Wan 1Fan Bai Cao 1Fang Feng 1Field Mint 2Fu Fang Xue Shuan Tong Capsule 1Fu Ling 2Fu Pen Zi 1Fu Zi 5Gan Cao 7Gan Cao Gan Jiang Tang 1Gan Mai Da Zao Tang 5Gan Mai Da Zao Wan 1Gao Ben 1Chaxiong 1Ge Gen 8Ginseng 2Gu Sui Bu 3Gui Pi Tang 2Gui Zhi 2Gui Zhi Fu Ling Wan 16Gui Zhi Shao Yao Zhi Mu Decoction 3Gui Zhi Tang 1Hou Po 1Hu Zhang 1Hua Jiao 4Hua Tan Huo Xue Prescription 1Huang Bai 2Huang Lian 5Huang Lian E Jiao Decoction 1Huang Lian Jie Du Tang 1Huang Qi 10Huang Qin 3Huangqi Xixin decoction 1Huo Xiang Zheng Qi 1Ji Gu Cao capsule 1Ji Sheng Shen Qi Wan 1Jia Wei Di Tan Tang 1Jia Wei Jing Jie Lian Qiao Tang 1Jia Wei Xiao Yao San 14Jian Pi Yi Shen Formula 7Jie Geng 2Jie Geng (Platycodon grandiflorum) 1Jin Yin Hua 2Jing Jie 1Juan Bi Tang 1Lei Gong Teng 2Lian Hua Qing Ke Li 1Lian Qiao 3Liu Jun Zi Tang 1Liu Wei Di Huang Wan 4Long Dan Xie Gan Tang 3Ma Huang 3Ma Huang Tang 1Mai Dong 1Man Jing Zi 1Mu Li 1Mu Zei 4Naoxintong Capsule 1Ningxin Tongyu Zishen Tang (NTZT) 1Niu Bang Zi 2Pei Tu Qing Xin Tang 1Pi Pa Qing Fei Yin 1Qi Ju Di Huang decoction 1Qi Ming Granule 1Qiang Huo 2Qing Dai 4Qing Fei Da Yuan Granules 1Qing Fei Pai Du Decoction 2Rou Cong Rong 1Ru Xiang 1Run Zao Zhi Yang Capsule 1San Qi 2Sang Ju Yin 1Sang Ye 4Sha Shen 4Sha Shen Mai Dong Decoction 1Shan Yao 1Shan Zhu Yu 1Shao Fu Zhu Yu Tang 1Shao Yao 4Shen Ling Bai Zhu San 5Shen Qi Wan 2Shen Yan Xiao Bai granule 1Sheng Ma 3Sheng Mai San 1Shi Quan Da Bu Tang 1Shi Wei Qing Wen Decoction 1Shu Feng Jie Du Capsule 1Shu Mian capsule 1Shuang Huang Lian 1Si Jun Zi Tang 2Si Ni Jia Ren Shen Decoction 1Si Ni San 1Si Ni Zuo Jin Decoction 1Si Wu Tang 9Suan Zao Ren 6Suan Zao Ren Tang 4Tai Zi Shen 1Tao He Cheng Qi Decoction 1Tao Hong Si Wu Tang 1Tian Ma 5Tian Ma Gou Teng decoction 1Tian Qi 1Tian Wang Bu Xin Dan 2Tong Yang Huo Xue Decoction 1Tu Si Zi 1Wen Dan Tang 9Wen Jing Tang 1Wen Xin Ke Li 4Wu Tou decoction 1Wu Wei Yu Gan Zi San 1Wu Wei Zi 8Xi Xian Cao 1Xi Xin 3Xia Ku Cao 4Xian He Cao 1Xian Ling Gu Bao Formula 3Xiang Fu 2Xiang Ru 1Xiang Sha Liu Jun Zi Tang 2Xiao Chai Hu Tang 2Xiao Hui Xiang 1Xiao Yao San 12Xin Yi 1Xin Yi Hua 1Xin Yi Qing Fei Tang 2Xu Duan 2Xuan Fei Bai Du decoction 1Xue Fu Zhu Yu Tang 3Yi Mu Cao 2Yi Qi Bu Shen Huo Xue decoction 1Yi Zhi Tong Xuan decoction 1Yin Huo Tang 1Yin Ma Jie Du Granule 1Yin Yang Huo 5You Gui Wan 5Yu Jen Cao 1Yu Nu Jian 1Yu Ping Feng San 14Yu Shen Yong Luo Granule 1Yu Xing Cao 3Yu Zhu 1Ze Xie Decoction 1Zhe Bei Mu 1Zhen Ren Huo Ming Yin 1Zhen Wu Decoction 2Zheng Yi Fang 1Zhi Bai Di Huang Wan 2Zhi Zhu Ma Ren pill 1Zhi Zi 2Zi Shen Yu Tai Wan 1Zi Su Ye 1Zuo Gui Wan 4

Adzuki Bean 11Almond 10Apple 4Apple Cider Vinegar 4Avocado 24Avocado Oil 3Avocado-Soybean Unsaponifiables 3Banana 2Bee Pollen 10Bitter Melon 2Black Pepper 3Blueberry 25Caraway 3Carrot 17Ceylon Cinnamon 8Chamomile 14Cherry 14Chilli 2Chinese Cinnamon 17Chrysanthemum 35Citrus Peel 4Cocoa 21Dark Chocolate 17Coffee 24Coix Seed 8Common Bean 2Cucumber 9Cumin 1Daikon 2Date Fruit 13Date Palm Pollen 2Eggplant 1Extra Virgin Olive Oil 13Fennel Seed 4Fenugreek 7Food Nutrients 1Carotene 4Iron 6Magnesium 14Omega-3 Fatty Acids 24Vitamin C 4Vitamin D 21Galangal 1Ginger 25Goji Berry 23Goji Berry Leaf 1Grapes 1Raisins 3Green Tea 62EGCG 23Matcha 6Honey 51Jujube 28Kiwifruit 37Lavender 14Lemongrass 3Lotus Seed 5Mediterranean Diet 7Mineral Water 22Mung Bean 6Mushroom 1Oats 9Peanut 5Pear 5Pecan 1Peppermint 8Peppermint Oil 5Plum 13Pomegranate 61Pomegranate Peel 8Pu-Erh Tea 16Gan Pu Tea 2Pumpkin 3Pumpkin Seed 14Raspberry 2Raspberry Leaf 5Raw Milk 7Rice Congee 4Saffron 17Sardine 12Sesame 3Sesame Oil 3Snow Fungus 15Soybean 21Black Soybean 4Miso 4Natto 2Soy Milk 2Spirulina 5Spring Onion 2Star Anise 1Strawberry 3Tomato 1Turmeric 10Walnut 28Watermelon 1Wheatgrass 1Yoghurt 1
Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study

2021 Oct 16   Gynecological Endocrinology   Grandi G, Del Savio MC, Melotti C, Feliciello L, Facchinetti F

The concomitant administration of VD and EGCG represents a promising treatment of UF in women of late reproductive life for which hormonal manipulation is not foreseen.

Clinical Study Vitamin D
Submitted by Jinnan C. 24 Oct 2023 - Added by Adrian Y. 28 Oct 2023
DOI 10.1080/09513590.2021.1991909

Insights & Discussion

Simultaneous administration of vitamin D and Epigallocatechin gallate significantly reduces the size of uterine fibroids in premenopausal women, and decreases menstrual flow duration.

In this study, 16 premenopausal women with uterine fibroids of varying sizes aged over 40 years old were given doses of Epigallocatechin gallate, Vitamin B6 and Vitamin D daily for 90 days. The women were selected based on specific criteria including their fibroid size and lack of other causes for abnormal uterine bleeding. Each woman kept a detailed daily diary recording details about their bleeding and pelvic pain.

The analysis of the data revealed that there was a noteworthy decrease in both the average size of fibroids for each woman and the size of individual fibroids. This effect was especially pronounced in women with predominantly intramural fibroids in comparison to subserosal fibroids. While menstrual cycle duration and intensity did not change, the length of menstrual flow was decreased. Uterine and ovarian volume as well as endometrial thickness did not exhibit any significant changes. The treatment was generally highly satisfactory to the participants, with no adverse effects reported.

— Jinnan C. 2 Jan 2024
Sign In

Sign in to comment on this article.

Sign In Create Account

Discover Related Insights

2022 Melatonin Research
Recent revelations of L-DOPA, dopamine, 5-hydroxytryptophan, tryptamine, serotonin, N-acetylserotonin, melatonin, 2-hydroxymelatonin, AFMK, AMK, and vitamin D3 derivatives in honey expand its health benefits.
Review Article Honey Melatonin Serotonin Vitamin D
Serotonin, melatonin and their precursors and metabolites and vitamin D3 derivatives in honey
Kim TK, Fabisiak A, Brzeminski P, Reiter RJ, Slominski AT
2022 BMJ Open
Vitamin D and Omega 3 fatty acids supplementation appears to reduce the risk of autoimmune diseases.
Cohort Study Autoimmune Disease Omega-3 Fatty Acids Vitamin D
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
Hahn J, Cook NR, Alexander EK, Friedman S, Walter J, Bubes V, et al.
2020 Molecules
We determined the concentration of 20(OH)D3 in honey to be 0.26 µg/g, corresponding to approximately 10 IU/g.
Experimental Study 20(OH)D3 Honey Vitamin D
Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey
Kim TK, Atigadda V, Brzeminski P, Fabisiak A, Tang EKY, Tuckey RC, et al.
2020 Molecules
Honey contains 20(S)-Hydroxyvitamin D3 (20(OH)D3) and its derivatives, including 20(OH)-7DHC, 25(OH)D3, and 1,25(OH)2D3, indicating their production in bees and suggesting potential health implications.
Experimental Study 20(OH)D3 Honey Vitamin D
Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey
Kim TK, Atigadda V, Brzeminski P, Fabisiak A, Tang EKY, Tuckey RC, et al.
2020 Nutrition Reviews
High doses of omega-3 fatty acids, Vitamin D supplementation, and dietary sodium restriction showed significant improvement in reducing rheumatoid arthritis symptoms.
Systematic Review Omega-3 Fatty Acids Rheumatoid Arthritis Vitamin D
Rheumatoid arthritis and dietary interventions: systematic review of clinical trials
Philippou E, Petersson SD, Rodomar C, Nikiphorou E
Sign In

Users not signed in are limited to viewing the 5 most recent items of content.

Sign In Create Account

Moderation Tools

Journal Cover
Article
Research Hub Content Disclaimer

The information on this website is provided for educational purposes only and should not be used to make any medical or health-related decisions without consulting a healthcare professional. The information contained in research papers should not be used as a substitute for professional medical advice, diagnosis, or treatment. Research papers may contain information that is not current or that may not apply to an individual's specific situation. It is important to always consult with a qualified healthcare professional before making any decisions about treatment or taking any new medication or supplements.

© 2025 Ping Ming Health® All Rights Reserved.