Enriching a regular diet with oat β-glucan can improve glycemic control, augment feelings of fullness, and positively modulate gut microbiota in individuals with type-2 diabetes.
Randomised Controlled Trial Blood Sugar Gut Microbiota HbA1C
The research involved 37 subjects with type-2 diabetes, who were required to consume either oat β-glucan or microcrystalline cellulose as a control dietary supplement each day for a period of 12 weeks. The parameters assessed throughout the study included fasting glucose, insulin, a variety of hormones and peptides regulating appetite (like ghrelin, leptin, GLP-1, PYY), caloric intake, and the profile of their intestinal microbiota.
The results indicated a decrease in HbA1c, insulin, C-peptide levels, as well as certain bacterial populations (Lactobacillus spp, and Butyrate-producing bacteria) in subjects who consumed β-glucan. Significant differences were observed in levels of certain hormones, namely leptin, GLP-1, and PYY, between the two groups. The intake of oat β-glucan emerged as a potential strategy to manage type-2 diabetes, by improving glycemic control, enhancing feelings of satiety, and fostering a healthier gut microbiota profile.
View Article