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The review reveals that nutritional supplements, particularly fish oils, vitamins, trace elements, and phytochemical extracts, show promising therapeutic potential for Dry Eye Disease management.
2024 Frontiers in Pharmacology Recommendations for nutritional supplements for dry eye disease: current advances Cong Y, Zhang Y, Han Y, Wu Y, Wang D, Zhang B
Systematic Review Dry Eye Omega-3 Fatty Acids
The methodology used in the research paper mainly focuses on evaluating different oral nutritional supplements with varied compositions and dosages, in order to assess their impact on Dry Eye Disease symptoms. These supplements include key components like fish oils, vitamins, trace elements, and extracts from plants, recognized for their potential nutritional value. Emphasizing the role of nutrition in combating ocular surface diseases, the research also emphasizes the imbalance caused by deficiencies in polyunsaturated fatty acids and vitamin insufficiencies, which can lead to ocular issues such as inflammation and oxidative stress.
The results discussion outlines considerable benefits of using these supplements, not only for managing Dry Eye Disease symptoms but also potentially for overall ocular health. It was observed that nutrients in these supplements hold promising therapeutic qualities, presenting new perspectives for supplement combinations in Dry Eye Disease treatment. Beyond the well-known nutrients, it was suggested that exploring novel nutrients could help establish even more effective management strategies for Dry Eye Disease.
Oat consumption can significantly improve lipid profiles, particularly reducing total cholesterol and LDL cholesterol, with potential positive effects on triglycerides and HDL cholesterol under certain conditions.
2023 Current Problems in Cardiology Effect of Oat (Avena sativa L.) Consumption on Lipid Profile With Focus on Triglycerides and High-density Lipoprotein Cholesterol (HDL-C): An Updated Systematic Review Amerizadeh A, Ghaheh HS, Vaseghi G, Farajzadegan Z, Asgary S
Systematic Review Cholesterol HDL-C Oats
In the methodology of this review study, information was gathered from various databases, including PubMed, Web of Science, and Google Scholar. The gathered data consisted of a total of 17 studies that explored the direct effects of oat consumption on lipid profiles. The focus of the studies included were the impacts of oat on levels of total cholesterol, VLDL, LDL-C, TG, and HDL-C. The review was meticulous, with a detailed examination of each study, particularly those showing positive effects of oat/beta-glucan consumption on triglycerides.
The review's results revealed that oat intake significantly reduces the levels of total cholesterol, VLDL, and LDL-C. The effect of oat ingestion on triglyceride levels was varied; of the 17 studies, 6 reported a decrease in triglycerides. Interestingly, one study showed an improvement in HDL-C levels following oat consumption. It was also observed that oat intake might effectively reduce triglycerides in healthy individuals and overweight people or those with diabetes or metabolic syndrome, especially when larger amounts of oat were consumed over a longer duration or in conjunction with a calorie-reducing diet. The use of oat together with certain dietary programs was suggested to potentially enhance its positive effects on lipid profiles.
Sardines, being an affordable source of Omega-3 and other cardioprotective nutrients, can potentially reduce the need for Omega-3 supplementation and manage cardiometabolic diseases.
2023 Frontiers in Nutrition Eating more sardines instead of fish oil supplementation: Beyond omega-3 polyunsaturated fatty acids, a matrix of nutrients with cardiovascular benefits Santos HO, May TL, Bueno AA
Review Article Cardiovascular Disease Cholesterol High Blood Pressure
The abstract primarily acknowledges the importance of Omega-3 polyunsaturated fatty acids with respect to managing diseases related to heart health and metabolism, for instance, type 2 diabetes, hypertension, hypertriglyceridaemia, and fatty liver disease. However, these fatty acids are not the sole beneficial component of sardines. Minerals including but not limited to calcium, potassium, and magnesium as well as substances like taurine and arginine found in sardines have a significant role in controlling mild inflammation and oxidative stress which are usually present in cardiovascular diseases and hemodynamic dysfunction.
The results discussed in the abstract suggest a positive correlation between consumption of sardines and potential cardiometabolic benefits. By considering the dose-response relationship effects, a pragmatic approach towards consumption of nutrients was suggested. The intake of sardines was seen not only as a means of Omega-3 supplementation but also as a comprehensive approach to enhancing cardiovascular health. The abstract concludes with an emphasis on the many beneficial nutrients found in sardines besides Omega-3, underlining the need to shift the focus from synthetic supplementation to natural dietary improvement.
Nutrition, particularly an anti-inflammatory Mediterranean diet supplemented with oily fish and omega-3 supplements, can potentially reduce inflammation and improve symptoms of rheumatoid arthritis.
2023 Autoimmunity Reviews Nutrition and its role in prevention and management of rheumatoid arthritis Nikiphorou E, Philippou E
Review Article Mediterranean Diet Omega-3 Fatty Acids Sardine
The review examines evidence indicating a possible connection between nutrition and the risk and management of rheumatoid arthritis, an autoimmune disease having an immune-inflammatory response. The impact of different food types was considered, including pro-inflammatory and anti-inflammatory foods. Specifically, the research highlights the effectiveness of a Mediterranean diet, rich in fish and supplemented with omega-3 polyunsaturated fatty acids, in reducing inflammation and oxidation. Other factors such as herbs and spices, beverages, vitamin D, and probiotics were also taken into account. The research emphasizes the direct and indirect role of nutrition through the management of co-morbidity.
The disease activity was observed to improve with dietary changes, particularly a propensity to reduce inflammation, oxidation, and beneficial effects on gut microbiota. An anti-inflammatory Mediterranean diet, supplemented with consumption of oily fish at least twice a week, and daily intake of omega-3 polyunsaturated fatty acid supplements of 2 g, has been recommended. The study also highlights the importance of rheumatologists working closely with registered dietitians to support patients in managing a well-balanced diet according to their individual needs.
Pomegranate consumption positively affects triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol levels.
2023 Journal of Functional Foods The effects of pomegranate consumption on lipid profile in adults: A systematic review and meta-analysis Bahari H, Rezaiian F, Goudarzi K, Nooshan Mirmohammadali S, Asbaghi O, sadat Hosseini kolbadi K, et al.
Systematic Review Cholesterol Pomegranate Triglyceride
To investigate the impact of pomegranate on lipid profiles, a comprehensive database search was completed up until June 2023, aiming to identify related trials. Statistically, the researchers employed the estimated 95% confidence and the weighted mean difference to measure the variables, including triglycerides, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. They employed a random-effects model for their analysis.
The meta-analysis revealed that pomegranate intake significantly reduces triglyceride levels. Still, it doesn't notably alter the total cholesterol concentrations. Additionally, consuming pomegranate seemed to have a diminishing impact on low-density lipoprotein cholesterol levels and an enhancing effect on high-density lipoprotein cholesterol levels.
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