Carotenoid-rich foods like orange carrots were more effective in mitigating Non-alcoholic fatty liver disease than those with low carotenoid levels.
Experimental Study Carrot NAFLD Orange
In this study, male C57BL/6J mice were randomly assigned to one of four experimental diets for a period of 15 weeks: a low-fat diet, a high-fat diet, a high-fat diet with 20% white carrot powders, or a high-fat diet with 20% orange carrot powders.
Observations revealed that those mice on the high-fat diet enriched with carotenoids from the orange carrots gained less weight and displayed less hepatic lipid deposition compared to the white carrot group. Moreover, lower levels of triglyceride content were seen in the orange carrot group. The increase of particular proteins indicated that carotenoids found in orange carrots improved β-oxidation, thereby inhibiting NAFLD development more significantly. Further examination showed noticeably higher mRNA and protein levels of a particular transcription factor.
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