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Kiwifruit supplementation may be associated with direct and indirect anticancer effects, the former likely due to ascorbic acid-mediated reduction of DNA oxidative injury and cytotoxic effect on cancer cell lines.
2019 Nutrition and Cancer Kiwifruit and Cancer: An Overview of Biological Evidence Lippi G, Mattiuzzi C
Review Article Kiwifruit
Overall, 58 items could be retrieved, fifty of which were excluded since they did not fulfilled all our search criteria. Eight studies (five in vitro studies, two human intervention trials, and one both in vivo and in human study) were finally included in this critical literature review.
Taken together, the results of these published studies suggest that kiwifruit supplementation may be associated with direct and indirect anticancer effects, the former likely due to ascorbic acid-mediated reduction of DNA oxidative injury and cytotoxic effect on cancer cell lines, the latter more likely attributable to enhanced daily bowel movements and increased intestinal fecal content of lactic acid bacteria, which would finally contribute to lower the risk of malignancies, especially colorectal cancer.