Insights & Discussion
Honey potentially has superior results than cough medication or placebo in curtailing symptoms and enhancing sleep in children with acute cough.
Methodology:
This targeted review leveraged multiple databases, such as PubMed, Scopus, CENTRAL, CINAHL, and Web of Science, to extract relevant trials relating to honey's usage in treating acute child cough. By applying a systematic approach, the emphasis was on randomized controlled trials featuring children. To ensure the results' credibility, payment was done for risk-of-bias as well as the quality of the evidence. The studies were not combined owing to the absence of essential information; instead, conclusions provided a range of noticed effects for principal results.
Discussion of results:
Following rigorous screening of almost four hundred papers, a select ten were incorporated. Significant variability in biases was noticed, with two studies possessing a high risk-of-bias and six inviting some concerns. The evidence, though of low to very low quality, indicated honey's potential superiority over placebo/no treatment and cough medication, both in reducing cough frequency and improving sleep quality.
Discover Related Insights
Honey is effective in treating coughs in children above 12 months.
2022 Cureus Journal of Medical Science Comparing the Effectiveness of Honey Consumption With Anti-Cough Medication in Pediatric Patients: A Systematic Review Mashat GD, Hazique M, Khan KI, Ramesh P, Kanagalingam S, Ul Haq Z, et al.
Systematic Review Cough Honey
The researchers undertook a systematic review of literature across five databases, using a Medical Subject Heading strategy, keywords, and defined inclusion and exclusion criteria to identify relevant studies. This review incorporated a range of study types, including systematic reviews, meta-analyses, randomized controlled trials, observational studies and cross-sectional studies. Those articles without a clear methodology section were excluded. The quality of the remaining literature was appraised using a specific checklist.
Following the review, it was found that honey is effective in treating coughs in children older than 12 months. Cold and cough medications were also found to be safe, if given at therapeutic doses. However, a note of caution was highlighted for the use of these medications in children under two years, as fatalities have been recorded in some cases; although further studies are recommended to establish a clear safety profile.
Parent-administered pediatric tuina is effective at reducing core symptoms of ADHD in preschool children and improves child appetite and sleep quality.
2022 Phytomedicine Parent-administered pediatric Tuina for attention deficit/hyperactivity disorder symptoms in preschool children: A pilot randomized controlled trial embedded with a process evaluation Chen SC, Yu J, Wang HS, Wang DD, Sun Y, Cheng HL, et al.
Randomised Controlled Trial ADHD Appetite Meridian Massage
This research involved a two-arm, parallel, open-label, pilot Randomized Controlled Trial, where 64 participants were assigned to two separate groups. Parents in the first group attended an online course teaching them pediatric tuina for ADHD, which they would then apply to their children at home. The second group of parents went through online training about a progressive muscle relaxation exercise and engaged in interactive physical activities with their children at home. Both groups carried out their respective interventions every other day for two month, each session lasting at least 20 minutes. The project measured the rate of recruitment, consent, participant adherence, retention and any adverse events.
Upon investigation, both groups demonstrated improvements, with moderate effect size within each group. This was reflected in improvements in core hyperactivity and impulsivity symptoms. Parents also noticed positive changes in their children’s eating habits, sleep quality, and overall parent-child relationship. No serious issues were reported in relation to implementing the parent-administered pediatric tuina or from the interactive physical activity sessions.
Honey is more effective than usual care alternatives for improving upper respiratory tract infection symptoms, particularly cough frequency and cough severity.
2020 BMJ Evidence-Based Medicine Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis Abuelgasim H, Albury C, Lee J
Systematic Review Antimicrobial Antimicrobial Resistance Cough
We identified 1345 unique records, and 14 studies were included. Overall risk of bias was moderate. Compared with usual care, honey improved combined symptom score, cough frequency. We combined two studies comparing honey with placebo for relieving combined symptoms.
Honey was superior to usual care for the improvement of symptoms of upper respiratory tract infections. It provides a widely available and cheap alternative to antibiotics. Honey could help efforts to slow the spread of antimicrobial resistance, but further high quality, placebo controlled trials are needed.
Honey can be used as an alternative to antibiotics by clinicians who wish to offer treatment for upper respiratory tract infections, which may help to combat antimicrobial resistance.
2020 BMJ Evidence-Based Medicine Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis Abuelgasim H, Albury C, Lee J
Systematic Review Antimicrobial Antimicrobial Resistance Cough
Upper respiratory tract infections (URTIs) are the most frequent reason for antibiotic prescription. Since the majority of URTIs are viral, antibiotic prescription is both ineffective and inappropriate. However, a lack of effective alternatives, as well as a desire to preserve the patient–doctor relationship, both contribute to antibiotic over prescription. Antibiotic overuse is a key driver of antimicrobial resistance, rated by the UK government as one of the top 10 risks facing Britain. Furthermore, drug resistant infections are associated with worse patient outcomes than antibiotic susceptible infections, underlining the impact of antimicrobial resistance on individual patients.
Moderate‐certainty evidence showed that honey probably reduces cough duration to a greater extent than salbutamol or placebo. Honey group participants were first to get total relief of cough compared to salbutamol or placebo.
2018 Cochrane Database of Systematic Reviews Honey for acute cough in children Oduwole O, Udoh EE, Oyo-Ita A, Meremikwu MM
Review Article Honey URTI
Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan. Honey probably reduces cough duration better than placebo and salbutamol. There was no strong evidence for or against using honey. Most of the children received treatment for one night, which is a limitation to the results of this review. There was no difference in occurrence of adverse events between the honey and control arms.
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