Insights & Discussion
Kidney tonic herbs may enhance bone density and reduce fracture risk in patients with primary osteoporosis.
This research gathered and analyzed data from 43 randomized controlled trials involving 4349 participants, selected through extensive scrutiny conducted by two researchers. The aim was to evaluate the effectiveness and safety of Kidney tonic herbs in the treatment of primary osteoporosis. A comprehensive search of literature across eight electronic databases was performed up to September 30, 2022. The main focus of these trials was changes in bone mineral density of the lumbar area.
The results, obtained through meta-analyses using RevMan 5.3 and Stata 16, indicated that kidney tonic herbs significantly increased bone mineral density in various anatomic sites. Examples of these are the lumbar area, femoral neck, and femoral trochanter. Moreover, the research found a decrease in fracture incidence, with no serious side effects reported. The herbs also showed superior pain relief potential. However, the impact of these herbs on fall incidence needs further exploration.
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Soy food intake, particularly fermented soy products, appear to have a protective effect on fracture risk among Asian women, especially in early menopause.
2021 Complementary Medicine Research Soy Foods and the Risk of Fracture: A Systematic Review of Prospective Cohort Studies Akhavan Zanjani M, Rahmani S, Mehranfar S, Zarrin M, Bazyar H, Moradi Poodeh B, et al.
Systematic Review Fracture Risk Osteoporosis
The research team carried out a systematic review of prospective cohort studies investigating the link between soy food intake and fracture risk. The databases searched were PubMed, Scopus, and Embase up to June 2021, and the team narrowed down 695 records to include 5 high-quality cohort studies. These selected studies were mostly conducted in China, Singapore and Japan and varied in their focus on different types of fractures. The dietary intake of soy food was assessed across all studies through face-to-face interviews.
In the analysis of the results, a promising relationship was found between the consumption of soy foods and a reduced risk of fractures among Asian women, notably for those in the early stages of menopause or those who consumed fermented soy products. In contrast, the association was not significant among men.