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Various types of genital mycoplasma infections are significantly linked to female infertility.
2021 American Journal of Reproductive Immunology The role of genital mycoplasma infection in female infertility: A systematic review and meta‐analysis Tantengco OAG, de Castro Silva M, Velayo CL
Systematic Review Female Fertility Mycoplasma
The researchers carried out a systematic review of literature to study the connection between genital mycoplasma infection and female infertility. They used three electronic databases, PubMed, Scopus, and CINAHL, to gather studies conducted between January 2000 and January 2020. They derived pooled odds ratios and confidence intervals from a fixed effects model to determine the likelihood of female infertility due to genital mycoplasma infection.
The gathered studies showed that women suffering from infertility had higher odds of having some form of genital mycoplasma infection. The meta-analysis included a total of eight studies from six different countries. Subgroup analysis indicated a significant relation of infertility with particular infections, namely, Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma urealyticum. This key finding supports the development of guidelines targeting the diagnosis and treatment of these infections as a means to prevent female infertility.