In this randomized clinical trial, 80 women of reproductive age diagnosed with polycystic ovary syndrome were divided into two groups – intervention and control. The intervention group was given a chamomile capsule three times a day over the course of 12 weeks. The control group received a placebo with the same prescription timing. The menstrual patterns and two androgens, testosterone and dehydroepiandrosterone, were evaluated before and after this three-month period.

The primary outcome observed was a significant increase in the number of participants with normal menstrual cycles in the chamomile capsules user group. Alongside this, a major improvement in the number of menstrual cycles after chamomile therapy was seen. A noteworthy decrease was also observed in testosterone levels amongst women in the intervention group whereas there was no significant change in the level of hormone dehydroepiandrosterone sulfate in either the intervention or control groups. This demonstrates that chamomile could potentially help regulate menstruation and decrease total testosterone levels in women struggling with polycystic ovary syndrome.