Insights & Discussion
Chamomile vaginal gel effectively improved the sexual function of postmenopausal women, and can be a potential treatment option for those unable to undergo hormone therapy.
The structured methodology involved a randomized, double-blind clinical trial, where 96 postmenopausal women with known sexual dysfunction were divided equally into three groups. Each group respectively received chamomile vaginal gel, conjugated estrogen vaginal cream, and placebo vaginal gel, for 12 weeks. The frequency of application varied over the course of the weeks. Measurements were made using the Female Sexual Function Index (FSFI) before and after the intervention. Data analysis implied chi-square, one-way ANOVA, descriptive statistics, and paired t-tests.
Despite the study's duration of 12 weeks, no follow-up was done past this time frame. The study also recorded experiences of side effects, with a few women reporting a burning sensation.
The results showed substantial improvement in all six sexual function domains and the total FSFI score for those women using chamomile vaginal gel when compared to the placebo. The chamomile gel showed no significant difference with the estrogen cream, except in the areas of orgasm and sexual satisfaction. This places chamomile vaginal gel as a considerable alternative for treating sexual dysfunction in postmenopausal women, especially for those who have contraindications to hormone therapy.
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Date palm pollen supplementation has shown significant positive impact on desire and lubrication in non-menopausal women's sexual function.
2022 Chinese Herbal Medicines Effect of date palm pollen supplementation on female sexual function in non-menopausal women: A double blind randomized clinical trial Salmani R, Nasiri K, Javadzadeh Y, Salmani R, Clark CCT, Aghamohammadi V
Randomised Controlled Trial Date Palm Pollen Female Sexual Function
In the study conducted between October and December of 2019, sixty-eight non-menopausal women were recruited from health centers in the city of Khalkhal for randomized clinical trials. The participants were divided into two study groups - a placebo group and a palm pollen group. The participants in the latter group received a dosage of 300mg per day of a palm pollen capsule for a duration of 35 days. The Female Sexual Function Index instrument was utilized to assess any changes in the participants' sexual function.
Following the introduction of the date palm pollen supplement, there was a noteworthy increase in two particular areas: desire and lubrication for the palm pollen group. While there were no discernible differences in other areas like arousal, orgasm, satisfaction, and pain, the overall sexual function, as per the Female Sexual Function Index, also experienced a positive increase. Even though each domain varied, there was an overall observed positive correlation between the initial levels and the resulting state following supplementation.
The combined use of chamomile and saffron with usual medication enhances the efficacy against depression and ensures long term improvement.
2022 Heliyon A randomized clinical trial to test efficacy of chamomile and saffron for neuroprotective and anti-inflammatory responses in depressive patients Ahmad S, Azhar A, Tikmani P, Rafique H, Khan A, Mesiya H, et al.
Randomised Controlled Trial Anti-Inflammatory Chamomile Neuroprotective
This research was a randomized, open, blinded trial with 120 participants split evenly into a test and control group. After consent was obtained, a patient health questionnaire was filled out to determine depression scores. Participants in the test group received herbal tea sachets, containing 20 mg of chamomile and 1 mg of saffron, twice per day for a month in addition to their regular medications. Control group participants only received their standard allopathic medicine. Blood samples were taken both before and after the treatment period.
The test showed significant improvement in depressive symptoms for both groups. However, in the test group, the addition of the herbal teas amplified the effect of the medications. The herbal adjuvant therapy reduced inflammatory markers and tryptophan levels in plasma, which increased the availability of tryptophan in the brain, a key aspect in managing depression. Consequently, the research concluded that inclusion of these herbs enhances the effectiveness of the conventional treatment against depression and provides long term benefits.
Chamomile sachets could be a viable alternate treatment for primary dysmenorrhea, as they've shown similar effects to mefenamic acid in reducing pain and bleeding.
2022 The Open Public Health Journal Comparing the Effect of Chamomile and Mefenamic Acid on Primary Dysmenorrhea Symptoms and Menstrual Bleeding: A Randomized Clinical Trial Shabani F, Narenji F, Vakilian K, Zareian MA, Bozorgi M, Bioos S, et al.
Randomised Controlled Trial Chamomile Mefenamic Acid Period Pain
In the methodology of this study, the researchers took 200 female students diagnosed with primary dysmenorrhea and divided them randomly into two groups. One group was given mefenamic acid and the other group was administered chamomile. The intensity of pain, related symptoms, and bleeding were assessed using various measurement scales.
Evaluating the results, both chamomile and mefenamic acid made a noticeable impact in decreasing the intensity of pain and bleeding. However, it was found that chamomile displayed a greater effectiveness in reducing the symptoms of primary dysmenorrhea, presenting it as a promising substitute treatment avenue.
Inhalation aromatherapy using lavender and chamomile essential oils effectively reduces depression, anxiety, and stress levels in community-dwelling older adults.
2022 Explore: The Journal of Science & Healing The effects of Lavender and Chamomile essential oil inhalation aromatherapy on depression, anxiety and stress in older community-dwelling people: A randomized controlled trial Ebrahimi H, Mardani A, Basirinezhad MH, Hamidzadeh A, Eskandari F
Randomised Controlled Trial Anxiety Chamomile Depression
From a methodological perspective, the researchers adopted a three-armed, parallel, randomized, and controlled trial design. A total of 183 participants were enrolled in the study and were randomly divided into three groups: lavender, chamomile, and control group with equal numbers in each. The individuals in the experimental groups were given three drops of 1.5% lavender and chamomile essential oils to inhale for 30 consecutive nights, while the control group inhaled distilled water in the same manner. The Depression, Anxiety, and Stress-Scale (DASS) was utilized to collect data both prior to the intervention, directly following the intervention, and a month after the treatment.
In terms of the results gathered, there was significant improvement in the depression, anxiety, and stress levels of individuals in the lavender and chamomile groups both immediately and one month after the treatment compared to the control group. This indicates that inhalation aromatherapy utilizing lavender and chamomile essential oils can be efficacious in reducing mental health issues among older adults residing in the community.
Chamomile can significantly improve menstrual regulation and decrease testosterone levels in women of reproductive age with polycystic ovary syndrome.
2022 Medicinal Plants - International Journal of Phytomedicines and Related Industries The effect of chamomile on menstruation pattern and serum androgens in polycystic ovary syndrome Heidary M, Dokuhaki S, Yazdanpanahi Z, Dabbaghmanesh MH, Emamghoreishi M, Akbarzadeh M
Randomised Controlled Trial Chamomile PCOS
In this randomized clinical trial, 80 women of reproductive age diagnosed with polycystic ovary syndrome were divided into two groups – intervention and control. The intervention group was given a chamomile capsule three times a day over the course of 12 weeks. The control group received a placebo with the same prescription timing. The menstrual patterns and two androgens, testosterone and dehydroepiandrosterone, were evaluated before and after this three-month period.
The primary outcome observed was a significant increase in the number of participants with normal menstrual cycles in the chamomile capsules user group. Alongside this, a major improvement in the number of menstrual cycles after chamomile therapy was seen. A noteworthy decrease was also observed in testosterone levels amongst women in the intervention group whereas there was no significant change in the level of hormone dehydroepiandrosterone sulfate in either the intervention or control groups. This demonstrates that chamomile could potentially help regulate menstruation and decrease total testosterone levels in women struggling with polycystic ovary syndrome.
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