Sleep quality in adults with disturbed sleep improved significantly after an 8-week course of naturally-derived sleep-inducing juice made from lettuce, orange, pineapple and cherry.
Randomised Controlled Trial Heart Rate Variability Lettuce Orange
This randomized, crossover study involved 25 adults (15 female, 10 male), all of whom reported difficulties in initiating or maintaining nighttime sleep. During the intervention, known as the feeding sessions (FS), the participants were given a sleep-inducing juice made of natural ingredients, being provided 250ml twice a day for 8 weeks. Their sleep quality and other related parameters were tracked with wearable actigraphs over seven consecutive days. The Pittsburgh sleep quality index (PSQI) scores were assessed before and after this juice intervention. The subjects' heart rate variability (HRV), both at rest and during sleep, was also closely monitored.
After the participants had undergone the 8-week juice intervention (FS), the PSQI scores decreased substantially, a change which directly correlated with a significant decrease in fatigue severity scale and visual analogue scale levels. Notably, heart rate variability indices indicative of vagal activity were significantly improved during the FS. The sleep efficiency and the total sleep time of the subjects increased significantly; at the same time, sleep latency and other disruptive factors like total counts, sleep fragmentation index, and movement index decreased significantly. There weren’t any significant differences observed during the non-feeding sessions (N-FS). Overall, the study results showed that the targeted intake of the sleep-inducing juice improved not only the sleep quality, but also led to an enhanced cardiac vagal tone during sleep.
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