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New approaches to the pathogenesis of peptic ulcer based on the protective action of saliva with special reference to roughage, vegetable fibre and fermented milk products
Article DOI: https://doi.org/10.1016/0306-9877(78)90021-X
New approaches to the pathogenesis of peptic ulcer based on the protective action of saliva with special reference to roughage, vegetable fibre and fermented milk products
Article DOI: https://doi.org/10.1016/0306-9877(78)90021-X

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New approaches to the pathogenesis of peptic ulcer based on the protective action of saliva with special reference to roughage, vegetable fibre and fermented milk products

2024 Jan   Psychoneuroendocrinology   Malhotra SL

Bile, rather than hydrochloric acid, is suggested to play a causative role in the development of peptic ulceration, with saliva playing a protective role through the presence of mucus. Consumption of roughage, cellulose, vegetable fibers, and fermented milk products could aid in preventing and curing peptic ulcers by increasing salivary mucus production.

Review Article Stomach Ulcer
Submitted by Jinnan C. 19 Nov 2024 - Added by Jinnan C. 24 Nov 2024
DOI 10.1016/0306-9877(78)90021-X

Insights & Discussion

Peptic ulcers may be prevented and cured by well-chewed food rich in vegetable fibers and fermented milk products, which increase protective salivary mucus and decrease damaging bile flow.

The research conducted a review of epidemiologic studies focusing on the variations of diet and eating patterns related to the prevalence of peptic ulcer disease across various communities. The effects of dietary patterns were assessed on saliva, gastric juice, and bile. The role of bile was specifically examined in the pathogenesis of peptic ulcer, with the argument that it, rather than hydrochloric acid, played a causal role. The role of saliva in preventing peptic ulcers was emphasized, particularly the protective nature of salivary mucus which is swallowed with food.

The study then suggested the types of diets that can help prevent peptic ulcers, including those rich in roughage, cellulose, vegetable fibers, and fermented milk products such as ghee and yogurt. The research posited this kind of diet can increase the amount of salivary mucus and consequently decrease the flow rate of harmful bile. The study also noted that these insights showed minor changes in diet, and a slower pace of consumption could lead to substantial health benefits.

Moving from dietary composition to eating behaviors, it was suggested that food should be well-masticated to ensure these beneficial digestive processes have an opportunity to occur. At the same time, the research made the case that specific dietary components, particularly short-chain fatty acids like those found in milk products, can retard gall bladder contraction, thereby reducing the amount of bile entering the duodenal lumen. This secondary action further contributes to the potential prevention of peptic ulcers.

— Research Hub A. 19 Nov 2024
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