Insights & Discussion
Seaweed extracts and polysaccharides are effective candidates for developing drugs and functional nutrition products to treat inflammatory bowel disease.
The methodology summarized in this research paper encompasses examining natural compounds, specifically derived from seaweed, which could potentially serve as therapeutic agents for IBD. Concentrating on the unique structural features of algal polysaccharides, the researchers observed their interaction with several factors associated with IBD, such as proinflammatory cytokines, chemokines, adhesion molecules, intestinal epithelial cells, and reactive oxygen and nitrogen.
In discussing the results, it was seen that the seaweed extracts and polysaccharides show promise in influencing key therapeutic targets related to IBD, suggesting their potential utility in the development of treatment options for patients. These include drugs, biological food additives, and functional nutrition products. This conclusion was drawn by noting the influence of these extracts and polysaccharides on immune and epithelial cells as well as intestinal microorganisms.
Discover Related Insights
Seaweed polysaccharides, especially those found in the cell walls of marine algae, hold significant potential as a natural, complementary treatment for Inflammatory Bowel Disease (IBD).
2023 Life The Role of Seaweed Polysaccharides in Gastrointestinal Health: Protective Effect against Inflammatory Bowel Disease Liyanage NM, Nagahawatta DP, Jayawardena TU, Jeon YJ
Digestive Health Inflammatory Bowel Disease Seaweed
The study analysed the therapeutic properties of sulfated polysaccharides, including carrageenan in red algae, ulvan in green algae, and fucoidan in brown algae, which are abundantly present in the cell walls of marine algae. Addressing key IBD pathologic treatment targets, the research explored polysaccharides' effects on inflammatory cytokines, adhesion molecules, intestinal epithelial cells, and intestinal microflora. These therapeutic targets were analyzed with an emphasis on utilizing natural substances like seaweed polysaccharides for improving IBD treatment efficacy.
Building upon the theory of a nutritional preventive mechanism for IBD and the restoration of intestinal health, the findings underscore the potent therapeutic capabilities of these natural compounds. Algal polysaccharides were found to have immense potential as a complementary treatment for IBD. It was suggested that these natural substances can be developed into effective drugs and functionally nutritious products, emphasizing a natural approach towards managing this global public health issue.