Insights & Discussion
The most important tremella mushroom benefits are anti-aging, anti-inflammatory, lower cholesterol, combat obesity, protect nerves and may fight cancer.
The most powerful nutritional constituents of Tremella are amino acids, vitamins, minerals, polysaccharides, Glucurmomannan 1,3-alpha-glucan, Epitope 9beta-D- glucuronosyl), Glucuronic acid, Glucurmic acid, Glucuronoxylomannan, N-acetylglucosamine, Flavonoids, Polyphenols, Alkaloids and Organic acids. Functional foods are making inroads into Chinese diets with their promises to improve health and nutrition. Chinese consumers should choose nutritional and healthy food to maintain general health and reduce the risk of health problems. Nutrition therapy on the basis of traditional Chinese medicine such tremella is quite effective at treating common diseases.
Discover Related Insights
A polysaccharide from Tremella aurantialba improves ulcerative colitis symptoms by targeting epithelial cell ferroptosis and modulating the gut microbiota.
2024 International Journal of Biological Macromolecules Tremella aurantialba polysaccharides alleviate ulcerative colitis in mice by improving intestinal barrier via modulating gut microbiota and inhibiting ferroptosis Peng G, Wang S, Zhang H, Xie F, Jiao L, Yuan Y, et al.
Animal Study Gut Microbiota Intestinal Barrier Ulcerative Colitis
The methodology used in this research involved isolating TA 2-1, a specific polysaccharide from Tremella Aurantialba, and studying its effects on ulcerative colitis. This was done by introducing it to Caco-2 cells that were undergoing ferroptosis and assessing its impact on cell viability. The influence of TA 2-1 was also examined in mice with artificially induced ulcerative colitis, verifying its ameliorating effects in an in-vivo context. The structure of TA 2-1 and its components were analysed and the polysaccharide's interaction with gut microbiota was explored to understand how it might modulate symptoms or prevent cell death.
The results of this study showed that TA 2-1 does not only decrease the rate of cell death in epithelial cells undergoing ferroptosis, but it also repairs the intestinal barrier by upregulating specific proteins such as claudin-1 and zonula occludens-1. TA 2-1 was also found to suppress lipid peroxidation, thus inhibiting ferroptosis. Further investigation revealed that TA 2-1 may alleviate ulcerative colitis by influencing the composition or metabolites of gut microbiota. This research offers promising insight into the potential of TA 2-1 in treating ulcerative colitis.
Goji berry leaves have stronger anti-colitis effects than mulberry leaves, ameliorating tissue damage and better regulating inflammatory responses and gut microbiota.
2023 Food & Function Goji berry leaf exerts a comparable effect against colitis and microbiota dysbiosis to its fruit in dextran-sulfate-sodium-treated mice Yu C, Chen Y, Ahmadi S, Wu D, Wu J, Ding T, et al.
Experimental Study Anti-Colitis Anti-Inflammatory Colitis
The research entailed a comparative study conducted on goji berry and mulberry leaves versus their respective fruits. To determine their anti-colitis effects, the experiment was administered to C57BL/6N mice that had been induced with colitis through dextran-sulfate-sodium. Through the utilization of measures such as ELISA and western blotting analysis, researchers were able to observe how each leaf versus its corresponding fruit ameliorated colitic symptoms, tissue damage, and was able to influence the overproduction of certain pro-inflammatory cytokines.
The results showed that both the goji berry leaf and fruit significantly reduced symptoms of colitis and improved tissue damage while the mulberry leaf did not show similar improvements. The goji berry leaf exhibited the strongest performance in restraining the overproduction of pro-inflammatory cytokines and further repairing the damaged colonic barrier. It also effectively adjusted gut microbiota equilibrium by increasing beneficial bacteria and decreasing harmful ones. The berries and leaves similarly restored certain dietary fibers to alleviate inflammation, but the mulberry leaf did not achieve this for butyrate. This is the first report to provide a comprehensive contrast of anti-colitis effects between the leaves and fruits of goji and mulberry.
Long-term consumption of green tea can potentially lessen the risk of depression in postmenopausal women by decreasing inflammation and boosting estradiol levels.
2023 Nutrients Long-Term Consumption of Green Tea Can Reduce the Degree of Depression in Postmenopausal Women by Increasing Estradiol Wan Z, Qin X, Tian Y, Ouyang F, Wang G, Wan Q
Cohort Study Anti-Inflammatory Depression Green Tea
In the study, researchers performed an analysis on a tea-producing village, incorporating 386 postmenopausal women in the investigation, who participated either as green tea consumers or non-drinkers (control group). The level of estradiol, inflammation markers, sleep quality, and depression symptoms were measured to uncover any correlations.
The results reflected significant disparities between the tea-drinking and control groups in terms of depression and insomnia levels, BMI, inflammation levels, and estradiol quantities. By appraising these outcomes, it was found that green tea intake could quell the likelihood of depression via its impact on sleep, inflammation, and estradiol levels. The risk of depression was consequently seen as reduced among postmenopausal women engaging in regular consumption of green tea.
Consumption of tea and coffee may possibly provide anti-inflammatory effects, contributing to reduced cardiovascular risk and mortality.
2023 Pharmacological Research Coffee or tea: Anti-inflammatory properties in the context of atherosclerotic cardiovascular disease prevention Surma S, Sahebkar A, Banach M
Review Article Anti-Inflammatory Cardiovascular Disease Coffee
The methodology of this narrative review examined the potential anti-inflammatory properties of consuming tea and coffee as a factor in reducing the risk of cardiovascular disease. This was done by analyzing a plethora of studies and meta-analyses that explored the impact of diet on inflammation, with a keen focus on the consumption of these beverages. The studies looked at a variety of risk factors for atherosclerotic cardiovascular disease, including inflammation biomarkers such as C-reactive protein, along with the impact of modern lipid-lowering treatments.
In discussing the results, it was noticed that inconsistent findings were produced from the analysed studies which made a conclusive determination challenging. However, a trend was observed where drinking tea and coffee seemed to raise adiponectin levels, reduce reactive oxygen species and lower low-density lipoprotein cholesterol levels. Despite these potential anti-inflammatory properties of tea and coffee being somewhat uncertain due to various confounding factors, their consumption is still recommended as part of a healthy diet.
Peppermint, particularly its component menthol, has been indicated to possess anti-inflammatory properties, potentially improving management of chronic disorders like diabetes and cancer.
2023 Phytotherapy Research Peppermint as a promising treatment agent in inflammatory conditions: A comprehensive systematic review of literature Goudarzi MA, Radfar M, Goudarzi Z
Systematic Review Anti-Inflammatory
Researchers searched four databases (Web of Sciences, PubMed, Scopus, and Embase) to identify articles relevant to peppermint and its anti-inflammatory effects. The search, conducted up to March 2023, led to the screening of 3805 records. From these, 14 articles were selected that met the study requirements. This extensive search and selection process aimed to cover as broad a range of reputable sources as possible, providing a holistic view of existing research on peppermint's potential anti-inflammatory capabilities.
In these studies, peppermint showed potential as an anti-inflammatory agent. Its hypothetical mechanism of action includes the activation of the AMP-activated protein kinase/unc-51 like kinase 1/nuclear factor-E2 associated factor 2 autophagy pathway. Concurrently, it might downregulate extracellular signal-regulated kinase-nuclear factor kappa B and mitogen-activated protein kinases pathways, thereby enabling inflammation suppression. Other likely pathways include attenuating oxidative stress and inhibiting the production of pro-inflammatory mediators and nitric oxide. Additionally, it may induce the production of anti-inflammatory prostaglandins. These combined pathways potentially lead to the overall reduction of inflammation. However, more human studies are required to confirm these beneficial effects.
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contains superoxide dismutase (SOD) which is a super antioxidant
— 20 Aug 2021