Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)

2020 Jan 6   Journal of Translational Medicine   Kim, DY., Lee, JS., Park, SY. et al.

This systematic review provides a comprehensive integration of previous RCTs for CFS/ME. Our data include characteristics of RCTs such as participants, case definitions, interventions and primary measurements. In addition, we found trends in the interventions used as well as in the overall results. Psychological treatments were predominant and had limitations curing CFS/ME. An exploration of the pathophysiology of CFS/ME and better development of treatments are needed.