Drug-Induced Liver Injury
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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Chrysanthemi Flosextract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis
2021 Jan 01 Pharmaceutical Biology Zhou Y, Wang C, Kou J, Wang M, Rong X, Pu X, et al.
Bianliang ziyu flower ethanol extract (BZE) demonstrated hepatoprotective effects in APAP-induced rats by alleviating liver pathological changes, reducing serum AST and ALT levels, and exhibiting antioxidant and anti-apoptotic activities. BZE (440 mg/kg) significantly reduced ROS levels, upregulated SOD and GSH, activated p-AMPK, p-GSK3β, HO-1, and NQO1, promoted nuclear translocation of Nrf2, inhibited apoptosis through the PI3K–Akt pathway, and restored mitochondrial biogenesis, suggesting its potential as a liver-protecting agent.
Experimental Study Network Pharmacology Acetaminophen Chrysanthemum Liver Injury Drug-Induced Liver Injury
Alleviation of Tramadol-Induced Liver Toxicity in Experimental Rats by Using Kiwifruit, Turmeric Extract or Their Combination
2019 Oct 01 Journal of Food and Dairy Sciences Elbadrawy E, Elkewawy H
It is recommended by using kiwifruit and turmeric extract in the diets of those who addicted to tramadol intake.
Animal Study Drug-Induced Liver Injury Liver Toxicity Turmeric Tramadol Kiwifruit Drug-induced Liver Injury (DILI)
Schisandra fruits for the management of drug-induced liver injury in China: A review
2019 Jun Phytomedicine Zhu P, Li J, Fu X, Yu Z
SF-derived drugs are effective in managing DILI. But this is what is happening in China. We hope that SF-derived drugs can benefit DILI patients all over the world in the near future. This review is expected to provide reference for people who are studying and prescribing SF-derived drugs.
Review Article Drug-Induced Liver Injury Drug-induced Liver Injury (DILI) Wu Wei ZiReview Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
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