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2014 Phytotherapy Research
Experimental Study Brain-Derived Neurotrophic Factor Jujube Neurotrophic Factor
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Chinese Medicine Research Hub
Experimental Study
Jujube fruit promotes the growth of nerve cells and boosts anti-oxidant enzyme production in brain cells.
2014 Phytotherapy Research A Chemically Standardized Extract of Ziziphus jujuba Fruit (Jujube) Stimulates Expressions of Neurotrophic Factors and Anti‐oxidant Enzymes in Cultured Astrocytes
Chen J, Yan AL, Lam KYC, Lam CTW, Li N, Yao P, Xiong A, Dong TTX, Tsim KWK
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Nerve Growth Factor" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Nerve Growth Factor" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Nerve Growth Factor" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Experimental Study published in 2014 in the journal Phytotherapy Research found that Jujube fruit promotes the growth of nerve cells and boosts anti-oxidant enzyme production in brain cells. The methodology focused on the application of a water extract from the jujube fruit to cultured astrocytes (star-shaped glial cells in the brain and spinal cord) and observing any resulting changes over a 24-hour period. Researchers utilized a protein kinase A inhibitor, H89, to ascertain if it lessened the apparent jujube-induced expression of neurotrophic factors, assessed in a concentration-dependent manner.
In the discussion of results, it was established that the jujube extract effectively stimulated the expression of several key neurotrophic factors including nerve growth factor, brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. These are pivotal in neural survival, growth, and differentiation. Concurrently, the extract also enhanced the transcriptional expressions of various significant enzymes responsible for anti-oxidation in a comparable concentration-dependent manner, indicating that jujube not only contributes to neural growth but also fosters the astrocytes' resistance to oxidative stress.
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