Oestrogen

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Chinese Medicine Research Hub

Review Article

Pumpkin seed oil, with its phytochemical content, shows beneficial properties against cardiovascular problems in menopausal women and hormone imbalances.

2022 Comprehensive Reviews in Food Science and Food Safety The potential of pumpkin seed oil as a functional food—A comprehensive review of chemical composition, health benefits, and safety
Šamec D, Loizzo MR, Gortzi O, Çankaya T, Tundis R, Suntar , Shirooie S, Zengin G, Devkota HP, Reboredo‐Rodríguez P, Hassan STS, Manayi A, Kashani HRK, Nabavi SM

Chinese Medicine Research Hub

The combinations of hop-derived polyphenols found in beer can collaboratively enhance estrogenic effects, especially when mixed with certain estrogenic pesticides.

2021 Frontiers in Nutrition Systemically Achievable Doses of Beer Flavonoids Induce Estrogenicity in Human Endometrial Cells and Cause Synergistic Effects With Selected Pesticides
Aichinger G, Bliem G, Marko D

Chinese Medicine Research Hub

Systematic Review

Phytoestrogens, used in various forms, have shown improvement in urogenital menopause symptoms and improved women's sexual function, promoting overall quality of life.

2021 European Journal of Obstetrics & Gynecology and Reproductive Biology Impact of phytoestrogens on treatment of urogenital menopause symptoms: A systematic review of randomized clinical trials
Abdi F, Rahnemaei FA, Roozbeh N, Pakzad R

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Oestrogen" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Oestrogen" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Oestrogen" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Review Article published in 2022 in the journal Comprehensive Reviews in Food Science and Food Safety found that Pumpkin seed oil, with its phytochemical content, shows beneficial properties against cardiovascular problems in menopausal women and hormone imbalances. The study focused on gathering scientific information that highlights the potential of pumpkin seed oil as a health-benefiting food ingredient. Its focus is on the oil’s chemical composition, phytochemical content, biological activity, safety measures alongside the various production processes. The researchers examined major phytochemicals found in the oil, including polyphenols, phytoestrogens, and fatty acids, while also noting the potential health benefits of carotenoids, squalene, tocopherols, and minerals present in it. In terms of methodology, most studies within this review were conducted in vitro to validate the oil's antioxidant and antimicrobial activities. Furthermore, there were clinical studies undertaken specifically to observe the effect of the oil in addressing cardiovascular challenges in menopausal women and conditions related to sex hormone imbalances. The comprehensive overview covers a wide array of data on the composition and potential uses of pumpkin seed oil.

A published in 2021 in the journal Frontiers in Nutrition found that The combinations of hop-derived polyphenols found in beer can collaboratively enhance estrogenic effects, especially when mixed with certain estrogenic pesticides. Researchers utilized the alkaline phosphatase assay testing on Ishikawa cells to investigate the combined estrogenic effects of three signature compounds - xanthohumol, 8-prenylnaringenin, and iso-xanthohumol which mirror their concentration ratios in beer. Additionally, the natural flavonoid pattern was added to a mixture of representative estrogenic pesticides to measure their combined effects. The results indicated cumulative to slightly synergistic effects between isolated flavonoids, as well as between the flavonoid and the pesticide mixtures. Notably, these impacts were observed at low nanomolar hop polyphenol concentrations, corresponding to levels realistically found after consumption of strongly hopped beer, suggesting a potential health concern.

A Systematic Review published in 2021 in the journal European Journal of Obstetrics & Gynecology and Reproductive Biology found that Phytoestrogens, used in various forms, have shown improvement in urogenital menopause symptoms and improved women's sexual function, promoting overall quality of life. A thorough and systematic review was conducted on databases including PubMed, EMBASE, Web of Science, Cochrane library, Scopus and ProQuest, spanning from the years 2000-2020. The focus was solely on randomized clinical trials. An evaluation of the quality of selected papers was carried out using the CONSORT checklist. In total, 33 high-quality papers were reviewed which discussed the different forms and uses of phytoestrogens. The results of this systematic review reveal that phytoestrogens including Pueraria Mirifica, fennel, Hop plant, Glycine Max, soy, red clover, black cohosh, ginsing, cimicifugaracemosa, genistein, diadzein, glycitein and isoflavone, used as various products such as oral capsules, pills, food supplements, enriched powders, vaginal gels, creams and suppositories, improved menopausal urogenital symptoms. Particularly, the recovery rate was found to be higher when these were applied vaginally. Further implication of these findings is the enhancement of women's sexual function following treatment, validating the use of phytoestrogens as a safe, low-risk and accessible method to alleviate urogenital symptoms.

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