Omega-6 Omega-3 Ratio

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Chinese Medicine Research Hub

Cohort Study

Certain oxylipins, which are bioactive lipids derived from omega-6 and omega-3 polyunsaturated fatty acids, are potential key influencers in arthritis in older adults.

2020 The Journals of Gerontology: Series A Imbalance Between Omega-6- and Omega-3-Derived Bioactive Lipids in Arthritis in Older Adults
Coras R, Pedersen B, Narasimhan R, Brandy A, Mateo L, Prior-Español A, Kavanaugh A, Armando AM, Jain M, Quehenberger O, Martínez-Morillo M, Guma M

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Omega-6 Omega-3 Ratio" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Omega-6 Omega-3 Ratio" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Omega-6 Omega-3 Ratio" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Cohort Study published in 2020 in the journal The Journals of Gerontology: Series A found that Certain oxylipins, which are bioactive lipids derived from omega-6 and omega-3 polyunsaturated fatty acids, are potential key influencers in arthritis in older adults. The research method involved an observational prospective study of 64 patients over the age of 60 with newly diagnosed arthritis, which was categorized as Elderly-onset rheumatoid arthritis and polymyalgia rheumatica. Patients' blood samples were taken at the start of the study and 3 months post-treatment, with results compared to 18 control samples. A thorough clinical examination was conducted for each patient. Serum oxylipins (bioactive lipids derived from omega-6 and omega-3 polyunsaturated fatty acids) were determined through mass spectrometry, and data analysis was performed. In the discussion, it was found that the levels of certain oxylipin species were significantly different between control subjects and arthritis patients. Interestingly, the ratio of omega-3 to omega-6 polyunsaturated fatty acids was significantly downregulated in elderly-onset rheumatoid arthritis patients compared to controls. Two oxylipins, namely hydroxydocosahexaenoic acid and dihydroxy-eicosatrienoic acid, were identified as top candidates for differentiating polymyalgia rheumatica from elderly-onset rheumatoid arthritis. Following treatment, the levels of omega-3 derived anti-inflammatory species increased in elderly-onset rheumatoid arthritis patients.

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