Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
How to submit an article:
- Registered users can submit any published journal article that has a unique DOI (Digital Object Identifier) name or link to Research Hub.
- For example, you can paste the full DOI link:
https://doi.org/10.1109/5.771073
or just the DOI name: 10.1109/5.771073
into the field above and click submit.
- The person who is first to submit a valid article to Research Hub will forever be credited for it, and every article submission earns you +6 Research Points.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Hydrogen carbonate-rich mineral water significantly reduces heartburn frequency and severity, improving quality of life with excellent tolerability.
Clinical Study GERD Mineral Water
This open, single-center, single-arm clinical pilot study involved 50 patients aged 18-64, suffering from heartburn at least twice weekly for over three months. Excluding those with severe diseases or on heartburn medication, participants drank 1.5 liters of hydrogen carbonate-rich mineral water daily for six weeks, with 300 ml consumed at each meal. The study included five visits for monitoring. Efficacy was assessed through patient self-assessments in a heartburn diary, symptom-specific questionnaires (Reflux Disease Questionnaire, Quality of Life in Reflux and Dyspepsia, Gastrointestinal Quality of Life Index), and overall health-related quality of life using the SF-12. Efficacy and safety were evaluated using the Wilcoxon test, χ2 test, and U-test, considering changes in symptoms and vital signs.
The study reported significant reductions in heartburn occurrences at week 6 in both the intention-to-treat and per-protocol populations. The average weekly heartburn episodes decreased by 5.1, and the duration of symptoms reduced by 19 minutes. Symptom frequency decreased in 89.6% of patients, and symptom duration in 79.2%. There were improvements in all dimensions of the RDQ and disease-specific quality of life. Both patients and investigators rated the water’s efficacy positively, with no serious adverse events reported. Additionally, a slight but significant decrease in both systolic and diastolic blood pressure was observed. The study concluded that hydrogen carbonate-rich mineral water is effective and well-tolerated in alleviating heartburn, enhancing quality of life.
View Article
Drinking hydrogen carbonate-rich mineral water significantly reduces heartburn episodes and improves quality of life in individuals with dyspeptic symptoms.
Clinical Study GERD Indigestion Mineral Water
This one-arm pilot study involved 56 men and women experiencing frequent heartburn. Participants were instructed to drink 1.5 liters of mineral water high in hydrogen carbonate daily for six weeks. They kept a daily diary to record the number and duration of heartburn episodes. Additionally, several questionnaires were used to assess the effects of the water on their condition and quality of life. These included the Reflux Disease Questionnaire (RDQ), Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD), Gastrointestinal Quality of Life Index (GILQI), and the Short Form Health Survey (SF-12). The study analyzed changes in symptoms and quality of life before and after the treatment using the Wilcoxon test.
The study reported a significant decrease in the number of weekly heartburn episodes and the duration of each episode after the six-week intervention. Participants also experienced a notable reduction in the severity of heartburn, regurgitation, and dyspeptic complaints. There was a significant improvement in disease-specific quality of life as measured by GILQI and QOLRAD, and in general health-related quality of life as assessed by SF-12. These findings suggest that drinking hydrogen carbonate-rich mineral water can be an effective alternative treatment for dyspeptic symptoms and heartburn, leading to an enhanced quality of life.
View Article
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
Published study protocols are detailed plans that outline the objectives, methodology, statistical analyses, and organisation of a research study that have been made publicly available for others to review and use as a reference.
Presentation Slides
Chinese Medicine Research Hub
Clinical Study
Hydrogen carbonate-rich mineral water significantly reduces heartburn frequency and severity, improving quality of life with excellent tolerability.
2016 World Journal of Gastrointestinal Pathophysiology Efficacy and tolerability of hydrogen carbonate-rich water for heartburn
Beer AM
Chinese Medicine Research Hub
Clinical Study
Drinking hydrogen carbonate-rich mineral water significantly reduces heartburn episodes and improves quality of life in individuals with dyspeptic symptoms.
2016 Open Journal of Gastroenterology Pilot Trial on the Efficacy and Safety of a Natural Mineral Water Rich in Hydrogen Carbonate on Functional Dyspepsia and Heartburn
Pohl U, Auinger A, Bothe G, Uebelhack R
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Hydrogen Carbonate" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Hydrogen Carbonate" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Hydrogen Carbonate" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Clinical Study published in 2016 in the journal World Journal of Gastrointestinal Pathophysiology found that Hydrogen carbonate-rich mineral water significantly reduces heartburn frequency and severity, improving quality of life with excellent tolerability. This open, single-center, single-arm clinical pilot study involved 50 patients aged 18-64, suffering from heartburn at least twice weekly for over three months. Excluding those with severe diseases or on heartburn medication, participants drank 1.5 liters of hydrogen carbonate-rich mineral water daily for six weeks, with 300 ml consumed at each meal. The study included five visits for monitoring. Efficacy was assessed through patient self-assessments in a heartburn diary, symptom-specific questionnaires (Reflux Disease Questionnaire, Quality of Life in Reflux and Dyspepsia, Gastrointestinal Quality of Life Index), and overall health-related quality of life using the SF-12. Efficacy and safety were evaluated using the Wilcoxon test, χ2 test, and U-test, considering changes in symptoms and vital signs.
The study reported significant reductions in heartburn occurrences at week 6 in both the intention-to-treat and per-protocol populations. The average weekly heartburn episodes decreased by 5.1, and the duration of symptoms reduced by 19 minutes. Symptom frequency decreased in 89.6% of patients, and symptom duration in 79.2%. There were improvements in all dimensions of the RDQ and disease-specific quality of life. Both patients and investigators rated the water’s efficacy positively, with no serious adverse events reported. Additionally, a slight but significant decrease in both systolic and diastolic blood pressure was observed. The study concluded that hydrogen carbonate-rich mineral water is effective and well-tolerated in alleviating heartburn, enhancing quality of life.
A Clinical Study published in 2016 in the journal Open Journal of Gastroenterology found that Drinking hydrogen carbonate-rich mineral water significantly reduces heartburn episodes and improves quality of life in individuals with dyspeptic symptoms. This one-arm pilot study involved 56 men and women experiencing frequent heartburn. Participants were instructed to drink 1.5 liters of mineral water high in hydrogen carbonate daily for six weeks. They kept a daily diary to record the number and duration of heartburn episodes. Additionally, several questionnaires were used to assess the effects of the water on their condition and quality of life. These included the Reflux Disease Questionnaire (RDQ), Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD), Gastrointestinal Quality of Life Index (GILQI), and the Short Form Health Survey (SF-12). The study analyzed changes in symptoms and quality of life before and after the treatment using the Wilcoxon test.
The study reported a significant decrease in the number of weekly heartburn episodes and the duration of each episode after the six-week intervention. Participants also experienced a notable reduction in the severity of heartburn, regurgitation, and dyspeptic complaints. There was a significant improvement in disease-specific quality of life as measured by GILQI and QOLRAD, and in general health-related quality of life as assessed by SF-12. These findings suggest that drinking hydrogen carbonate-rich mineral water can be an effective alternative treatment for dyspeptic symptoms and heartburn, leading to an enhanced quality of life.