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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Dietary supplements for treatment of endometriosis: A review
2022 Mar 14 Acta Biomedica Yalçın Bahat P, Ayhan I, Üreyen Özdemir E, İnceboz Ümit, Oral E
Review ArticleDietary supplements are found to be a promising complementary treatment for endometriosis, thanks to their anti-inflammatory, anti-oxidant, and immune modulatory characteristics.
Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
2021 Jun 04 Frontiers in Nutrition Ferreira RLU, Sena-Evangelista KCM, de Azevedo EP, Pinheiro FI, Cobucci RN, Pedrosa LFC
Preliminary clinical studies indicate promising results of selenium supplementation, particularly in patients with selenium deficiency, in the management of inflammatory bowel disease (IBD). However, further randomized clinical trials are necessary to comprehensively assess the short-term and long-term effects on both active and quiescent IBD.
Clinical Study Review Article Selenium
The rationale for selenium supplementation in inflammatory bowel disease: A mechanism-based point of view
2021 May Nutrition Ala M, Kheyri Z
Selenium supplementation exhibits antiinflammatory properties through selenoproteins, contributing to oxidative stress attenuation, remission in animal models of colitis, support for protective gut microbiota, and potential blocking of tumorigenesis pathways. Preliminary clinical studies suggest promising results, especially in patients with selenium deficiency, but further randomized clinical trials are required to assess the short-term and long-term effects on both active and quiescent IBD.
Experimental Study Review Article Selenium
Selenium and inflammatory bowel disease
2015 Jul 15 American Journal of Physiology-Gastrointestinal and Liver Physiology Kudva AK, Shay AE, Prabhu KS
Selenium, incorporated into selenoproteins, plays a pivotal role in the modulation of gastrointestinal inflammation by influencing macrophage function and driving a switch from a proinflammatory to an anti-inflammatory phenotype. This phenotypic plasticity, accompanied by changes in cytokines, chemokines, and bioactive metabolites, contributes to the resolution of inflammation in the gut and restoration of epithelial barrier integrity. The review highlights the importance of selenium-dependent regulation of arachidonic acid metabolism and emphasizes the role of macrophages in supporting resolution in IBD.
Theoretical Article Review Article Selenium Irritable Bowel SyndromeResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Dietary supplements are found to be a promising complementary treatment for endometriosis, thanks to their anti-inflammatory, anti-oxidant, and immune modulatory characteristics.
2022 Acta Biomedica Dietary supplements for treatment of endometriosis: A review Yalçın Bahat P, Ayhan I, Üreyen Özdemir E, İnceboz Ümit, Oral E
Review Article
The researchers conducted a comprehensive literature review and synthesized the effects of various dietary supplements. The list of supplements includes vitamin D, zinc, magnesium, omega 3, propolis, quercetin, curcumin, N-acetylcysteine, probiotics, resveratrol, alpha lipoic acid, vitamin C, vitamin E, selenium, and epigallocatechin-3-gallate. These were studied due to their known anti-inflammatory, anti-oxidant, anti-proliferative, and immune modulatory characteristics.
In terms of discussion on the results, the findings from the comprehensive literature review, encompassing in vitro, animal and human studies, show that there might be significant potential for dietary supplements as a complementary treatment to conventional therapy for endometriosis. Each supplement displayed attributes contributing to the mitigation of endometriosis symptoms, whether it was through anti-inflammatory means, antioxidant effects, immune modulation or their anti-proliferative properties. Despite variations between different kinds of supplements, the overall consensus indicates these function as a helpful add-on in managing the disease.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Dietary supplements for treatment of endometriosis: A review
2022 Mar 14 Acta Biomedica Yalçın Bahat P, Ayhan I, Üreyen Özdemir E, İnceboz Ümit, Oral E
Review ArticleDietary supplements are found to be a promising complementary treatment for endometriosis, thanks to their anti-inflammatory, anti-oxidant, and immune modulatory characteristics.
Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
2021 Jun 04 Frontiers in Nutrition Ferreira RLU, Sena-Evangelista KCM, de Azevedo EP, Pinheiro FI, Cobucci RN, Pedrosa LFC
Preliminary clinical studies indicate promising results of selenium supplementation, particularly in patients with selenium deficiency, in the management of inflammatory bowel disease (IBD). However, further randomized clinical trials are necessary to comprehensively assess the short-term and long-term effects on both active and quiescent IBD.
Clinical Study Review Article SeleniumThe rationale for selenium supplementation in inflammatory bowel disease: A mechanism-based point of view
2021 May Nutrition Ala M, Kheyri Z
Selenium supplementation exhibits antiinflammatory properties through selenoproteins, contributing to oxidative stress attenuation, remission in animal models of colitis, support for protective gut microbiota, and potential blocking of tumorigenesis pathways. Preliminary clinical studies suggest promising results, especially in patients with selenium deficiency, but further randomized clinical trials are required to assess the short-term and long-term effects on both active and quiescent IBD.
Experimental Study Review Article SeleniumSelenium and inflammatory bowel disease
2015 Jul 15 American Journal of Physiology-Gastrointestinal and Liver Physiology Kudva AK, Shay AE, Prabhu KS
Selenium, incorporated into selenoproteins, plays a pivotal role in the modulation of gastrointestinal inflammation by influencing macrophage function and driving a switch from a proinflammatory to an anti-inflammatory phenotype. This phenotypic plasticity, accompanied by changes in cytokines, chemokines, and bioactive metabolites, contributes to the resolution of inflammation in the gut and restoration of epithelial barrier integrity. The review highlights the importance of selenium-dependent regulation of arachidonic acid metabolism and emphasizes the role of macrophages in supporting resolution in IBD.
Theoretical Article Review Article Selenium Irritable Bowel SyndromePresentation Slides
Dietary supplements are found to be a promising complementary treatment for endometriosis, thanks to their anti-inflammatory, anti-oxidant, and immune modulatory characteristics.
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