Hypoglycemic Effect

Presentation Slides

Chinese Medicine Research Hub

Animal Study

Ripened Pu-erh tea extract demonstrates a stronger anti-diabetic impact than raw Pu-erh tea extract, potentially due to the fermentation process and its probiotic benefits to certain gut bacteria.

2019 RSC Advances Comparison of hypoglycemic effects of ripened pu-erh tea and raw pu-erh tea in streptozotocin-induced diabetic rats
Qianzhi Ding, Wei Zheng, Bowei Zhang, Xiaojuan Chen, Jie Zhang, Xu Pang, Yong Zhang, Dexian Jia, Surui Pei Yuesheng Dong Baiping Ma

Chinese Medicine Research Hub

Case Report

Raspberry leaf consumption may decrease insulin requirements in pregnant women with gestational diabetes mellitus.

2016 Obstetrics & Gynecology Raspberry Leaf and Hypoglycemia in Gestational Diabetes Mellitus
Cheang KI, Nguyen TT, Karjane NW, Salley KES

Chinese Medicine Research Hub

Experimental Study

Pumpkin seeds and their extracts, including Trigonelline, Nicotinic acid, and D-chiro-inositol, offer potential for controlling blood sugar levels in diabetes patients.

2014 Critical Reviews in Food Science and Nutrition The Hypoglycemic Effect of Pumpkin Seeds, Trigonelline (TRG), Nicotinic Acid (NA), and D-Chiro-inositol (DCI) in Controlling Glycemic Levels in Diabetes Mellitus
Adams GG, Imran S, Wang S, Mohammad A, Kok MS, Gray DA, Channell GA, Harding SE

Executive Summary

Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Hypoglycemic Effect" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.

Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Hypoglycemic Effect" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.

Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Hypoglycemic Effect" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.

A Animal Study published in 2019 in the journal RSC Advances found that Ripened Pu-erh tea extract demonstrates a stronger anti-diabetic impact than raw Pu-erh tea extract, potentially due to the fermentation process and its probiotic benefits to certain gut bacteria. The methods of the study involved the processing and analysis of Pu-erh tea leaves, specifically the raw variety and the ripened type which goes through pile-fermentation. To identify differences in the anti-diabetic effects of both types, the researchers subjected their extracts to ultra-high-performance liquid chromatography paired with quadrupole-time-of-flight mass spectrometry (UHPLC-Q-TOF/MS) and UHPLC coupled with photodiode array (PDA) analyses. These techniques helped in identifying new compounds formed and those that increased due to the fermentation. The research also performed a study observing the effects of Ripened Pu-erh Tea on beneficial gut bacteria, namely Lactobacillus, Bifidobacterium, Akkermansia, and Roseburia. In their discussion, the researchers noted that the ripened Pu-erh tea extract exhibited more potent anti-diabetic effects on two key indicators of diabetes: two-hour postprandial blood glucose and fasting blood glucose. This superiority over the raw Pu-erh tea extract was attributed to 17 newly formed components and those that increase after fermentation such as quinic acid, gallic acid, caffeine, and puerin I. Furthermore, ripened Pu-erh tea showed to have a probiotic role on certain beneficial gut bacteria, implying an extra potential avenue for its anti-diabetic effects.

A Case Report published in 2016 in the journal Obstetrics & Gynecology found that Raspberry leaf consumption may decrease insulin requirements in pregnant women with gestational diabetes mellitus. In the methodology of this case study, a 38-year-old pregnant woman, who was diagnosed with gestational diabetes mellitus, consumed raspberry leaf tea at 32 weeks of gestation. After the ingestion of the tea, she experienced hypoglycemia that required lowering her insulin dosage. This temporal relationship was verified by her ceasing and readopting the herb. Throughout the study, there were reassuring fetal surveillance and growth, resulting in a cesarean delivery at 39 weeks. The newborn didn't have hypoglycemia or any other complications and the placental biopsy showed standard outcomes. In the discussion of the results, it was observed that raspberry leaf tea might have properties that can affect glycemic control in gestational diabetes mellitus patients. After consumption of the tea, the subject experienced hypoglycemia which necessitated a decrease in her insulin dose. Also, the re-consumption of the herb confirmed its hypoglycemic effects. Importantly, the baby was not affected by hypoglycemia or any other complications, indicating that raspberry leaf tea may be a practical alternative for managing gestational diabetes mellitus. However, it was recommended that pregnant women with such condition should be cautious about the use of the herb and monitor their glucose levels more frequently.

A Experimental Study published in 2014 in the journal Critical Reviews in Food Science and Nutrition found that Pumpkin seeds and their extracts, including Trigonelline, Nicotinic acid, and D-chiro-inositol, offer potential for controlling blood sugar levels in diabetes patients. The study investigated the hypoglycemic properties of pumpkins, specifically focusing on the seeds. A variety of biologically active ingredients found in pumpkins were analyzed, these include polysaccharides, para-aminobenzoic acid, fixed oils, sterols, proteins, and peptides, with an emphasis on the macromolecules such as Trigonelline, Nicotinic acid, and D-chiro-inositol. A key aspect of the methodology was examining the role these chemicals play in maintaining glycemic control, by investigating the effects of fruit pulp, ungerminated seed oil, and protein from germinated seeds. In the discussion of results, the study indicated that chemicals within pumpkins do have hypoglycemic properties, suggesting the potential use of pumpkins, particularly their seeds, in controlling or managing blood sugar levels in diabetes patients. Specific macromolecules within the seeds, Trigonelline, Nicotinic acid, and D-chiro-inositol, also suggested hypoglycemic properties. These results underline the potential that pumpkin and its biologically active ingredients could offer an innovative approach to dealing with diabetes mellitus.

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