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2023 Complementary Therapies in Medicine
Randomised Controlled Trial Gut Microbiota Hot Flushes Plant-Based Diet Soybean
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Chinese Medicine Research Hub
Randomised Controlled Trial
Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
2023 Complementary Therapies in Medicine A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis
Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, Hata E, Znayenko-Miller T, Holubkov R, Barnard ND
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Low Fat Diet" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Low Fat Diet" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Low Fat Diet" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Randomised Controlled Trial published in 2023 in the journal Complementary Therapies in Medicine found that Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes. In this study, 84 postmenopausal women experiencing two or more moderate-to-severe hot flashes daily were randomly assigned to a low-fat, vegan diet with daily cooked soybeans or allowed to maintain their usual diet. Over a 12-week period, the frequency and severity of hot flashes were tracked using a mobile application. In 11 women from the group, gut microbiome was analyzed at the start and after 12 weeks of the dietary intervention, using deep shotgun metagenomic sequencing.
The women who underwent gut microbiome testing experienced a substantial decrease in total hot flashes during the dietary intervention, and severe hot flashes disappeared entirely in this group. Alpha and beta diversity within the microbiome showed no significant difference in the intervention group between baseline and the end of the 12 weeks. Interestingly, adjustments in the relative abundance of certain bacterial strains, notably Porphyromonas and Prevotella corporis, were linked with the reduction in severe day hot flashes, while changes in the relative abundance of Clostridium asparagiforme were associated with a reduction in total severe hot flashes and severe night hot flashes.