Drug Interaction
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Coffee consumption can significantly alter the absorption, distribution, metabolism, and excretion of many drugs, leading to varied therapeutic responses.
Drug Interaction
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
The genus Asarum: A review on phytochemistry, ethnopharmacology, toxicology and pharmacokinetics
2022 Jan Journal of Ethnopharmacology Liu H, Wang C
Based on this review, therapeutic potential of genus Asarum has been demonstrated with the pharmacological effects on inflammation, CNS, respiratory regulation, cardiovascular diseases, cancer and microbial infection. The available literature showed that the major activities of the genus Asarum can be attributed to the active lignans and essential oils. Further in-depth studies on the aspects of the genus for mechanism of actions, metabolism, pharmacokinetics, toxicology, drug interactions, and clinical trials are still limited, thereby intensive research and assessments should be performed.
Review ArticleThe Effect of Coffee on Pharmacokinetic Properties of Drugs : A Review
2020 Jul 25 BioMed Research International Belayneh A, Molla F
Review Article Drug InteractionCoffee consumption can significantly alter the absorption, distribution, metabolism, and excretion of many drugs, leading to varied therapeutic responses.
Effects of Jia-Wei-Xiao-Yao-San on the Peripheral and Lymphatic Pharmacokinetics of Paclitaxel in Rats
2016 Jan JAMA Oncology Hou ML, Lu CM, Tsai TH
Our findings demonstrate that when paclitaxel is prescribed concurrently with herbal medicine, monitoring of the blood pharmacokinetics of paclitaxel is recommended.
Animal StudyResearch Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Coffee consumption can significantly alter the absorption, distribution, metabolism, and excretion of many drugs, leading to varied therapeutic responses.
2020 BioMed Research International The Effect of Coffee on Pharmacokinetic Properties of Drugs : A Review Belayneh A, Molla F
Review Article
The methodology involved a comprehensive review of research findings, clinical case reports, and expert panels from various reputable sources. These sources ranged from dedicated scientific databases such as Scopus, PubMed, Hindawi, OVID, Embase, and the Cochrane Library, to the broader database of Google Scholar, and the research-intensive Web of Science.
In terms of results, it was found that the simultaneous consumption of coffee significantly impacts the pharmacokinetics of many drugs. This can result in a heightened therapeutic response, a failure of the therapeutic response, or even toxic reactions. As a result, it's suggested that the concurrent consumption of coffee and medications that interact significantly with coffee should be avoided. It's advised that there should be an appropriate time gap between drug intake and coffee based upon the specific properties of the drug. Both pharmacists and clinicians should be aware of these potential risks of drug-coffee interaction.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
The genus Asarum: A review on phytochemistry, ethnopharmacology, toxicology and pharmacokinetics
2022 Jan Journal of Ethnopharmacology Liu H, Wang C
Based on this review, therapeutic potential of genus Asarum has been demonstrated with the pharmacological effects on inflammation, CNS, respiratory regulation, cardiovascular diseases, cancer and microbial infection. The available literature showed that the major activities of the genus Asarum can be attributed to the active lignans and essential oils. Further in-depth studies on the aspects of the genus for mechanism of actions, metabolism, pharmacokinetics, toxicology, drug interactions, and clinical trials are still limited, thereby intensive research and assessments should be performed.
Review ArticleThe Effect of Coffee on Pharmacokinetic Properties of Drugs : A Review
2020 Jul 25 BioMed Research International Belayneh A, Molla F
Review Article Drug InteractionCoffee consumption can significantly alter the absorption, distribution, metabolism, and excretion of many drugs, leading to varied therapeutic responses.
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Coffee consumption can significantly alter the absorption, distribution, metabolism, and excretion of many drugs, leading to varied therapeutic responses.
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