Chemotherapy-induced peripheral neuropathy (CIPN)
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Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.

Acupuncture improves chemotherapy-induced neuropathy explored by neurophysiological and clinical outcomes – The randomized, controlled, cross-over ACUCIN trial
2022 Sep Phytomedicine Friedemann T, Kark E, Cao N, Klaßen M, Meyer-Hamme G, Greten JH, et al.
Clinical Study Randomised Controlled Trial Chemotherapy Acupuncture Neuropathy Chemotherapy-Induced Peripheral NeuropathyAcupuncture has shown potential in enhancing structural nerve regeneration in Chemotherapy-induced peripheral neuropathy, leading to subjective improvements and positive neurological findings.

Clinical Efficacy and Potential Mechanisms of Acupoint Stimulation Combined With Chemotherapy in Combating Cancer: A Review and Prospects
2022 Apr 25 Frontiers in Oncology Li S, Zhao S, Guo Y, Yang Y, Huang J, Wang J, et al.
In conclusion, the evidence suggests that acupoint stimulation can alleviate the side effects of chemotherapy and can also assist chemotherapeutic agents in inhibiting tumor growth, which expands the clinical application of acupoint stimulation in cancer treatment.
Review Article
External Treatment With Chinese Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
2022 Feb 18 Frontiers in Pharmacology Li Q, Cai F, Lu Y, Liu H, Wang X, Li F, et al.
Chinese herbal medicine (CHM) external treatment was found to be an effective method for treating chemotherapy-induced peripheral neuropathy (CIPN) as it significantly improved clinical symptoms and quality of life in patients with CIPN.
Systematic Review Meta-Analysis Chemotherapy-induced peripheral neuropathy (CIPN) Chinese Herbal Medicine Chemotherapy-Induced Peripheral Neuropathy
The Efficacy of Acupuncture in Chemotherapy-Induced Peripheral Neuropathy: Systematic Review and Meta-Analysis
2019 Jan Integrative Cancer Therapies Chien TJ, Liu CY, Fang CJ, Kuo CY
Acupuncture demonstrated significant improvements in pain scores and nervous system symptoms based on Functional Assessment of Cancer Therapy/Neurotoxicity questionnaire scores; however, no significant change was noted in nerve conduction velocity. The study suggests that acupuncture can effectively relieve CIPN pain and functional limitations, but larger-scale studies are needed due to the limited number of subjects.
Meta-Analysis Systematic Review Chemotherapy-Induced Peripheral Neuropathy AcupunctureResearch insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
2022 Phytomedicine
Acupuncture has shown potential in enhancing structural nerve regeneration in Chemotherapy-induced peripheral neuropathy, leading to subjective improvements and positive neurological findings.
Clinical Study Acupuncture Chemotherapy Chemotherapy-Induced Peripheral Neuropathy Neuropathy
Acupuncture improves chemotherapy-induced neuropathy explored by neurophysiological and clinical outcomes – The randomized, controlled, cross-over ACUCIN trial
Friedemann T, Kark E, Cao N, Klaßen M, Meyer-Hamme G, Greten JH, et al.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.

Clinical Efficacy and Potential Mechanisms of Acupoint Stimulation Combined With Chemotherapy in Combating Cancer: A Review and Prospects
2022 Apr 25 Frontiers in Oncology Li S, Zhao S, Guo Y, Yang Y, Huang J, Wang J, et al.
In conclusion, the evidence suggests that acupoint stimulation can alleviate the side effects of chemotherapy and can also assist chemotherapeutic agents in inhibiting tumor growth, which expands the clinical application of acupoint stimulation in cancer treatment.
Review Article
External Treatment With Chinese Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
2022 Feb 18 Frontiers in Pharmacology Li Q, Cai F, Lu Y, Liu H, Wang X, Li F, et al.
Chinese herbal medicine (CHM) external treatment was found to be an effective method for treating chemotherapy-induced peripheral neuropathy (CIPN) as it significantly improved clinical symptoms and quality of life in patients with CIPN.
Systematic Review Meta-Analysis Chemotherapy-induced peripheral neuropathy (CIPN) Chinese Herbal Medicine Chemotherapy-Induced Peripheral Neuropathy
The Efficacy of Acupuncture in Chemotherapy-Induced Peripheral Neuropathy: Systematic Review and Meta-Analysis
2019 Jan Integrative Cancer Therapies Chien TJ, Liu CY, Fang CJ, Kuo CY
Acupuncture demonstrated significant improvements in pain scores and nervous system symptoms based on Functional Assessment of Cancer Therapy/Neurotoxicity questionnaire scores; however, no significant change was noted in nerve conduction velocity. The study suggests that acupuncture can effectively relieve CIPN pain and functional limitations, but larger-scale studies are needed due to the limited number of subjects.
Meta-Analysis Systematic Review Chemotherapy-Induced Peripheral Neuropathy AcupunctureClinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Study Protocols
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Presentation Slides

Clinical Study
Acupuncture has shown potential in enhancing structural nerve regeneration in Chemotherapy-induced peripheral neuropathy, leading to subjective improvements and positive neurological findings.
Friedemann T, Kark E, Cao N, Klaßen M, Meyer-Hamme G, Greten JH, Rostock M, Buhlmann E, Zhao A, Schröder S
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Chemotherapy-induced peripheral neuropathy (CIPN)" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Chemotherapy-induced peripheral neuropathy (CIPN)" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Chemotherapy-induced peripheral neuropathy (CIPN)" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Clinical Study published in 2022 in the journal Phytomedicine found that Acupuncture has shown potential in enhancing structural nerve regeneration in Chemotherapy-induced peripheral neuropathy, leading to subjective improvements and positive neurological findings. This research was conducted at the HanseMerkur Center for TCM at the University Medical Center, Hamburg-Eppendorf. Sixty patients who had been diagnosed with Chemotherapy-induced peripheral neuropathy underwent acupuncture treatment. Patients were selected based on physical examinations, subjective and quantitative evaluations conducted using nerve conduction studies. They were then randomly divided into two groups. The first group received a ten-week acupuncture treatment while the latter was put on a waiting list. After fourteen weeks, evaluations were carried out on both groups. The second group then received the acupuncture treatment while group one was put on the waiting list. Both groups were subjected to another evaluation after 28 weeks. The results showed noticeable improvements in sural sensory nerve amplitude and sural nerve conduction velocity among patients who received acupuncture treatment. This can be seen in the subjective improvements reported by the patients in the form of reduced burning pain, cramps, numbness, frequency of symptoms and improved gait. Significantly positive findings from the physical examination, including blind walking, heel-to-toe walking, and distal pallhypesthesia further bolster the potential benefits of acupuncture treatment in managing Chemotherapy-induced peripheral neuropathy.
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