Restless Legs Syndrome
Recent Insights
The traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.
Restless Legs Syndrome Shao Yao Gan Cao Tang
Standard acupuncture was significantly more effective for restless legs syndrome severity than control conditions.
Restless Legs Syndrome
The severity of primary restless legs syndrome symptoms can be significantly ameliorated by acupuncture.
Insomnia Restless Legs Syndrome
The combination of acupuncture and a low dose of gabapentin (300 mg/d) is clinically effective in treating restless legs syndrome and has an additional therapeutic benefit compared to gabapentin alone.
Restless Legs Syndrome
Related Topics
Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Effect of Self-developed Ye’an Analgetic Decoction/Jiawei Shaoyao Gancao Decoction Combined with Tramadol on TCM Symptom Scores and RLS Severity of patients with Restless Legs Syndrome
2024 Mar 18 Pakistan Journal of Medical Sciences Zhou B, Li W, Li Y, Sun D, Du X
The self-developed Ye’an Analgetic Decoction/Jiawei Shaoyao Gancao Decoction significantly improves clinical symptoms, reduces RLS severity, and enhances quality of life and sleep quality in RLS patients more effectively than basic treatment with tramadol alone.
Randomised Controlled Trial Clinical Study Shao Yao Gan Cao Tang Tramadol Restless Legs Syndrome
Acupuncture Treatment for Restless Legs Syndrome: A Review of Randomized Controlled Trials
2023 Nov 30 Journal of Acupuncture Research Chae GE, Kim HW, Jo HJ, Koh A, Lee YJ, Choi JE, et al.
Acupuncture demonstrates significant improvements in overall health, treatment efficacy rate, sleep quality, and quality of life indicators for patients with RLS, as evidenced by reductions in pain severity (VAS scores), RLS symptoms severity (IRLSRS scores), and absence of significant side effects. Acupuncture is suggested as an effective and safe treatment for RLS, though further large-scale RCT studies are warranted to validate these findings.
Review Article Acupuncture Restless Legs SyndromeEfficacy and safety of Shaoyao Gancao Tang for restless leg syndrome: A systematic review and meta-analysis
2023 Feb 12 Quality Assurance and Safety of Crops & Foods Tian Z, Li R, Wei J, Huai W, Xia J, Jiang H, et al.
Meta-Analysis Systematic Review Shao Yao Gan Cao Tang Restless Legs SyndromeThe traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.
Alternative treatment of restless legs syndrome: an overview of the evidence for mind-body interventions, lifestyle interventions, and neutraceuticals
2020 Jan Sleep Medicine Bega D & Malkani R
Insufficient evidence exists for yoga, acupuncture, PCDs, near-infrared light therapy, CBT, valerian, or Chinese herbs, but preliminary studies on each of these suggest that high-quality randomized controlled trials may be warranted to support and verify the data presented.
Randomised Controlled Trial Restless Legs SyndromeNon-pharmacological interventions for restless legs syndrome: a systematic review of randomised controlled trials
2018 Mar 21 Disability and Rehabilitation Harrison EG, Keating JL, Morgan PE.
Systematic Review Restless Legs SyndromeStandard acupuncture was significantly more effective for restless legs syndrome severity than control conditions.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
The traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.
2023 Quality Assurance and Safety of Crops & Foods Efficacy and safety of Shaoyao Gancao Tang for restless leg syndrome: A systematic review and meta-analysis Tian Z, Li R, Wei J, Huai W, Xia J, Jiang H, et al.
Meta-Analysis Shao Yao Gan Cao Tang
The methodology used for this study involved a systematic review and meta-analysis of Randomized Clinical Trials (RCTs) assessing the efficacy and safety of SG-Tang treatment for Restless Leg Syndrome. Databases such as the Cochrane Library, PubMed, EMBASE, Web of Science, Chinese Biological Medicine Database, China National Knowledge Infrastructure, Wanfang Database, and VIP Information Database were searched. The primary and secondary outcome measurements looked at were the total effective rate, the International Restless Legs Syndrome Study Group Rating Scale for Severity of Restless Legs Syndrome, the Pittsburgh Sleep Quality Index, and the incidence of adverse events.
The results of the study indicated that SG-Tang treatment led to significant improvements compared to conventional medications; it increased the total effective rate and lifted scores on the Severity of Restless Legs Syndrome and Sleep Quality Indices, while also lessening the incidence of adverse events. However, these conclusions should be interpreted with caution due to the limited data and the methodological quality of the included studies.
Standard acupuncture was significantly more effective for restless legs syndrome severity than control conditions.
2018 Disability and Rehabilitation Non-pharmacological interventions for restless legs syndrome: a systematic review of randomised controlled trials Harrison EG, Keating JL, Morgan PE.
Systematic Review
The current management of restless leg syndrome is primarily pharmacological, and medications can have unwanted side effects.
Repetitive transcranial magnetic stimulation, exercise, compression devices, counterstrain manipulation, infrared therapy, and standard acupuncture may reduce restless leg syndrome severity.
Vibration pads, cryotherapy, yoga, compression devices, and acupuncture may improve some sleep-related outcomes in restless leg syndrome.
Non-pharmacological interventions for RLS may cause placebo effects and rehabilitation professionals should control for this possibility in future investigations.
The combination of acupuncture and a low dose of gabapentin (300 mg/d) is clinically effective in treating restless legs syndrome and has an additional therapeutic benefit compared to gabapentin alone.
2017 Journal of Acupuncture and Meridian Studies Evaluation of Acupuncture in the Treatment of Restless Legs Syndrome: A Randomized Controlled Trial Raissi GR, Forogh B, Ahadi T, Ghahramanpoori S, Ghaboussi P, Sajadi S
Randomised Controlled Trial
The study aimed to investigate the effectiveness of medical acupuncture as an additional treatment to gabapentin for controlling restless legs syndrome (RLS) symptoms. Forty-six RLS patients were randomly assigned to either receive 10 sessions of acupuncture plus gabapentin or gabapentin alone over four weeks, with their symptoms assessed before, immediately after, and eight weeks after treatment. Results showed that the experimental group had significantly better improvements in VAS, IRLSRS, and PSQI compared to the control group. After the treatment, both groups had significant improvements in VAS and IRLSRS, while only the experimental group had a significant improvement in PSQI.
The severity of primary restless legs syndrome symptoms can be significantly ameliorated by acupuncture.
2017 Sleep Medicine Reviews Complementary and alternative therapies for restless legs syndrome: An evidence-based systematic review Xu XM, Liu Y, Jia SY, Dong MX, Cao D, Wei YD.
Systematic Review Insomnia
Complementary and alternative therapies have been found to be effective in both primary and secondary restless legs syndrome (RLS). The severity of primary RLS symptoms can be significantly ameliorated by exercise training, transcutaneous spinal direct current stimulation, pneumatic compression devices, light therapy, repetitive transcranial magnetic stimulation, and acupuncture. Pneumatic compression devices and yoga also improve RLS-related disorders. Exercise training is highly efficacious in the reduction of symptom severity in uremic RLS and related effects such as poor quality of life. Endovenous laser ablation may be a good choice for patients with concurrent RLS and superficial venous insufficiency.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Acupuncture Treatment for Restless Legs Syndrome: A Review of Randomized Controlled Trials
2023 Nov 30 Journal of Acupuncture Research Chae GE, Kim HW, Jo HJ, Koh A, Lee YJ, Choi JE, et al.
Acupuncture demonstrates significant improvements in overall health, treatment efficacy rate, sleep quality, and quality of life indicators for patients with RLS, as evidenced by reductions in pain severity (VAS scores), RLS symptoms severity (IRLSRS scores), and absence of significant side effects. Acupuncture is suggested as an effective and safe treatment for RLS, though further large-scale RCT studies are warranted to validate these findings.
Review Article Acupuncture Restless Legs SyndromeEfficacy and safety of Shaoyao Gancao Tang for restless leg syndrome: A systematic review and meta-analysis
2023 Feb 12 Quality Assurance and Safety of Crops & Foods Tian Z, Li R, Wei J, Huai W, Xia J, Jiang H, et al.
Meta-Analysis Systematic Review Shao Yao Gan Cao Tang Restless Legs SyndromeThe traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.
Non-pharmacological interventions for restless legs syndrome: a systematic review of randomised controlled trials
2018 Mar 21 Disability and Rehabilitation Harrison EG, Keating JL, Morgan PE.
Systematic Review Restless Legs SyndromeStandard acupuncture was significantly more effective for restless legs syndrome severity than control conditions.
Complementary and alternative therapies for restless legs syndrome: An evidence-based systematic review
2017 Jun 19 Sleep Medicine Reviews Xu XM, Liu Y, Jia SY, Dong MX, Cao D, Wei YD.
Systematic Review Insomnia Restless Legs SyndromeThe severity of primary restless legs syndrome symptoms can be significantly ameliorated by acupuncture.
Clinical Trials
Clinical trials are research studies that involve people and are conducted to evaluate the safety and efficacy of new treatments or interventions, such as drugs, medical devices, or behavioural therapies.
Effect of Self-developed Ye’an Analgetic Decoction/Jiawei Shaoyao Gancao Decoction Combined with Tramadol on TCM Symptom Scores and RLS Severity of patients with Restless Legs Syndrome
2024 Mar 18 Pakistan Journal of Medical Sciences Zhou B, Li W, Li Y, Sun D, Du X
The self-developed Ye’an Analgetic Decoction/Jiawei Shaoyao Gancao Decoction significantly improves clinical symptoms, reduces RLS severity, and enhances quality of life and sleep quality in RLS patients more effectively than basic treatment with tramadol alone.
Randomised Controlled Trial Clinical Study Shao Yao Gan Cao Tang Tramadol Restless Legs SyndromeAlternative treatment of restless legs syndrome: an overview of the evidence for mind-body interventions, lifestyle interventions, and neutraceuticals
2020 Jan Sleep Medicine Bega D & Malkani R
Insufficient evidence exists for yoga, acupuncture, PCDs, near-infrared light therapy, CBT, valerian, or Chinese herbs, but preliminary studies on each of these suggest that high-quality randomized controlled trials may be warranted to support and verify the data presented.
Randomised Controlled Trial Restless Legs SyndromeEvaluation of Acupuncture in the Treatment of Restless Legs Syndrome: A Randomized Controlled Trial
2017 Oct Journal of Acupuncture and Meridian Studies Raissi GR, Forogh B, Ahadi T, Ghahramanpoori S, Ghaboussi P, Sajadi S
Randomised Controlled Trial Restless Legs SyndromeThe combination of acupuncture and a low dose of gabapentin (300 mg/d) is clinically effective in treating restless legs syndrome and has an additional therapeutic benefit compared to gabapentin alone.
Actigraph Evaluation of Acupuncture for Treating Restless Legs Syndrome
2015 Feb 11 Evidence-Based Complementary and Alternative Medicine Pan W, Wang M, Li M, Wang Q, Kwak S, Jiang W, et al.
Standard but not randomized acupuncture reduced the abnormal leg activity of nocturnal activity and early sleep activity. No side effects were observed. The results indicate that standard acupuncture might improve the abnormal leg activity in restless legs syndrome patients and thus is a potentially suitable integrative treatment for long-term use.
Randomised Controlled Trial Restless Legs SyndromePresentation Slides
The traditional Chinese herbal medicine Shaoyao Gancao Tang (SG-Tang) may be an effective and safe alternative treatment to relieve Restless Leg Syndrome.
Standard acupuncture was significantly more effective for restless legs syndrome severity than control conditions.
The combination of acupuncture and a low dose of gabapentin (300 mg/d) is clinically effective in treating restless legs syndrome and has an additional therapeutic benefit compared to gabapentin alone.
The severity of primary restless legs syndrome symptoms can be significantly ameliorated by acupuncture.
Sign In
Users not signed in are limited to viewing the 5 most recent items of content.