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Protective effect of ZYMT, a traditional Chinese patent medicine in a mouse model of retinitis pigmentosa
2023 Jun Biomedicine & Pharmacotherapy Huang Z, Huang Q, Xu K, Liang L, Li Y, Zhou W, et al.
Experimental Study Animal Study Dang Shen Shu Di Huang Huang Qi Ge Gen Goji Berry Zhang Yan Ming Tablets Retinitis Pigmentosa Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
Zhangyanming Tablets (ZYMT) has been in clinical use for almost 4 decades. The main components of this medicine include Fructus Lycii (wolfberry), Radix Codonopsis, Radix Astragali, Radix Puerariae Lobatae, Radix Rehmanniae Praeparata and so on. —Jinnan C 25 Apr 2024
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Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
Experimental Study Dang Shen Ge Gen Goji Berry
Eighty mice with Retinitis Pigmentosa (RP) were divided into two groups, with one group receiving Zhangyanming Tablets (ZYMT) and a control group getting distilled water. After a period of 7 and 14 days, the researchers conducted tests through electroretinogram, fundus photography, and histological examination to assess the retinal function and structure of the subjects. They furthered the study using TUNEL, immunofluorescence and qPCR to evaluate cell apoptosis and the expressions of particular genes.
The ZYMT-treated mice displayed a notable enhancement in retinal reactions and overall preservation of retinal structure when compared to the control group. Particularly noticeable were increases in retinal thickness and cell count, alongside a significantly lowered rate of cell death. A comprehensive follow-up shows the altered expressions of several genes in the retina following the application of ZYMT. These results, combined, suggest a key role of ZYMT in mitigating the effects of RP especially in early stages.
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Review Articles
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Chinese Medicine Research Hub
Experimental Study
Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
2023 Biomedicine & Pharmacotherapy Protective effect of ZYMT, a traditional Chinese patent medicine in a mouse model of retinitis pigmentosa
Huang Z, Huang Q, Xu K, Liang L, Li Y, Zhou W, Ning N, Zhou J, Hu J, Liu S, Dang L
Executive Summary
Write an executive summary in the form of a blog article on the topic of "Research into Chinese medicine treatment for Zhang Yan Ming Tablets" summarising the research below and using language that can be easily understood by patients and avoiding medical jargon using a professional and caring tone of voice.
Write an executive summary in the form of a blog article on the topic of "Researched Chinese medicine treatments for Zhang Yan Ming Tablets" summarising the research below in an objective and easy to understand way, and using language that can be easily understood by patients. Group the article into Chinese medicine treatments first, followed by nutrition and other treatments. Avoid using medical jargon and use a professional and caring tone of voice.
Write me a concise but easy to understand executive summary on the topic of "Chinese medicine treatments for Zhang Yan Ming Tablets" based on the following research that I will give you. Your summary should be 2 paragraphs long in Australian English spelling and include references to the studies.
A Experimental Study published in 2023 in the journal Biomedicine & Pharmacotherapy found that Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties. Eighty mice with Retinitis Pigmentosa (RP) were divided into two groups, with one group receiving Zhangyanming Tablets (ZYMT) and a control group getting distilled water. After a period of 7 and 14 days, the researchers conducted tests through electroretinogram, fundus photography, and histological examination to assess the retinal function and structure of the subjects. They furthered the study using TUNEL, immunofluorescence and qPCR to evaluate cell apoptosis and the expressions of particular genes.
The ZYMT-treated mice displayed a notable enhancement in retinal reactions and overall preservation of retinal structure when compared to the control group. Particularly noticeable were increases in retinal thickness and cell count, alongside a significantly lowered rate of cell death. A comprehensive follow-up shows the altered expressions of several genes in the retina following the application of ZYMT. These results, combined, suggest a key role of ZYMT in mitigating the effects of RP especially in early stages.
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Zhangyanming Tablets show potential as a protective agent for retinal function in early-stage, genetically-caused blindness in mice, possibly due to their antioxidant and anti-/pro-apoptotic properties.
Zhangyanming Tablets (ZYMT) has been in clinical use for almost 4 decades. The main components of this medicine include Fructus Lycii (wolfberry), Radix Codonopsis, Radix Astragali, Radix Puerariae Lobatae, Radix Rehmanniae Praeparata and so on. —Jinnan C 25 Apr 2024