Sesame
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Recent Insights
Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
Blood Sugar Sesame
The studies assessed showed that sesame could have a significant effect on oxidative stress and the antioxidant defense system, being considered a food with an important antioxidant function in the different populations studied.
Sesame
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Research Articles
Published research studies are articles that present the findings of original research that has undergone a peer-review process and has been made publicly available in scholarly journals, books or other media.
Food and nutraceutical functions of sesame oil: An underutilized crop for nutritional and health benefits
2022 Sep Food Chemistry Langyan S, Yadava P, Sharma S, Gupta NC, Bansal R, Yadav R, et al.
Sesame oil, despite being an under-utilized minor crop, is rich in nutrients such as lignans, tocopherols, phytosterols, natural antioxidants, and bioactive compounds. The review underscores its various health benefits, including anti-lipogenic, hypo-cholesterolemic, anti-degenerative, and neural health-promoting properties. The study emphasizes the need for more research to explore sesame oil's food and nutraceutical potential, positioning it as a valuable candidate for maintaining diversity in food oils and improving human health.
Theoretical Article Review Article Sesame OilNutritional and Therapeutic Potential of Sesame Seeds
2022 Apr 22 Journal of Food Quality Abbas S, Sharif MK, Sibt-e-Abbas M, Fikre Teferra T, Sultan MT, Anwar MJ
The study concludes that sesame seeds and oil have significant potential in the pharmaceuticals, nutraceuticals, and food industries, particularly in snack production.
Review Article Sesame seeds Nutrition Sesame
Hypolipidemic effect of Sesame Seed Oil: A Review
2022 Apr 30 Pakistan BioMedical Journal Arshad M, Ashfaq M, Rizwan B, Zanib R, Fatima A, Pervaiz R, et al.
Sesame seed oil and its derivatives have shown to be highly effective in managing hyperlipidemia and dyslipidemia due to their lipid ameliorating and anti-oxidative effects.
Experimental Study Review Article Cholesterol Sesame Oil HypercholesterolemiaConsumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials
2022 Jan 18 Phytotherapy Research Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Meta-Analysis Blood Sugar SesameConsumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
Sesame Seed and Its Fractions for Improving Oxidative Stress in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials
2019 Nov 06 Food Reviews International Moghtaderi F, Ramezani-Jolfaie N, Raeisi-Dehkordi H, Salehi-Abargouei A
Systematic Review Meta-Analysis Oxidative Stress AntioxidantSesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants.
Research Insights
Insights are moderated by the Research Hub team and offer an at-a-glance overview of interesting research findings.
Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
2022 Phytotherapy Research Consumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Blood Sugar
The methodology involved conducting a systematic review and meta-analysis on the effect of sesame seeds consumption on blood glucose and insulin resistance in adults. The researchers gathered data from recognized academic resources like PubMed/MEDLINE, SCOPUS, Web of Science, Google Scholar, and EMBASE, which included controlled clinical trials up until February 2021. The sesame products in these trials ranged from sesame oil, sesamin, and tahini, with the intervention period lasting from 45 days to 9 weeks.
The results illustrate that the intake of sesame and its products significantly improved fasting blood glucose and Hemoglobin A1c levels. Nonetheless, the results regarding fasting serum insulin and the homeostatic model assessment for insulin resistance were not found to have any significant relation. Hence, the consumption of sesame might be a beneficial supplement for managing glucose levels in humans.
Sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants.
2019 Food Reviews International Sesame Seed and Its Fractions for Improving Oxidative Stress in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials Moghtaderi F, Ramezani-Jolfaie N, Raeisi-Dehkordi H, Salehi-Abargouei A
Systematic Review Antioxidant Oxidative Stress
Meta-analyses revealed that sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants. However, no significant effect was observed on malondialdehyde (MDA), total antioxidant capacity and α-tocopherol levels. It was shown that MDA levels significantly decreases only when sesame seeds were used for supplementation. Sesame consumption is associated with improved oxidative status. High quality randomized controlled clinical trials from diverse regions are still needed.
Sesame oil intake was associated with reduced body weight and body mass index.
2018 Journal of Functional Foods Do sesame seed and its products affect body weight and composition? A systematic review and meta-analysis of controlled clinical trials Raeisi-Dehkordi H, Mohammadi M, Moghtaderi F, Salehi-Abargouei A
Systematic Review Sesame Oil
A number of studies suggested that sesame products improve body weight and composition. This was the first meta-analysis of the effect of sesame on body weight and composition. Ten controlled clinical trials were eligible to be included in the systematic review. Sesame supplementation improved body fat percent and body adiposity index. Sesame oil intake was associated with reduced body weight and body mass index. Sesame consumption did not affect other indices of body composition.
The biomarkers that were significantly different between black seeds and white sesame seeds are highly related to the functions recorded in traditional Chinese medicine.
2018 Molecules Identification of Nutritional Components in Black Sesame Determined by Widely Targeted Metabolomics and Traditional Chinese Medicines Wang D, Zhang L, Huang X, Wang X, Yang R, Mao J, et al.
Systematic Review
Chemical composition of secondary metabolites is of great importance for quality control of agricultural products. Black sesame seeds are significantly more expensive than white sesame seeds, because it is thought that black sesame seeds are more beneficial to human health than white sesame seeds. However, the differences in nutrient composition between black sesame seeds and white sesame seeds are still unknown. The current study examined the levels of different metabolites in black and white sesame seeds via the use of a novel metabolomics strategy. Using widely targeted metabolomics data, we obtained the structure and content of 557 metabolites, out of which 217 metabolites were identified, and discovered 30 metabolic pathways activated by the secondary metabolites in both black and white sesame seeds. Our results demonstrated that the main pathways that were differentially activated included: phenylpropanoid biosynthesis, tyrosine metabolism, and riboflavin metabolism. More importantly, the biomarkers that were significantly different between black seeds and white sesame seeds are highly related to the functions recorded in traditional Chinese medicine. The results of this study may serve as a new theoretical reference for breeding experts to promote the genetic improvement of sesame seeds, and therefore the cultivation of higher quality sesame varieties.
Of the 7 clinical trials included, five evaluating individuals with hypertension observed a significant reduction in systolic and/or diastolic blood pressure. The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile.
2017 Critical Reviews in Food Science and Nutrition The effect of dietary intake of sesame (Sesamumindicum L.) derivatives related to the lipid profile and blood pressure: A systematic review Carolina Alves Cardoso, Gláucia Maria Moraes de Oliveira, Luciana de Almeida Vittori Gouveia, Annie Seixas Bello Moreira & Glorimar Rosa
Systematic Review Cholesterol
The mechanisms of action are still being studied. Regarding the bias risk analysis, clinical trials included showed few descriptions of the methods applied. There are few studies about sesame ingestion, and it was observed high risk for bias in the selected studies. More standardized methods with attention to the design of studies are needed to improve the level of the evidence.
Review Articles
Review articles summarise and critically evaluate the current state of research on a specific topic or field by synthesising multiple primary research studies.
Food and nutraceutical functions of sesame oil: An underutilized crop for nutritional and health benefits
2022 Sep Food Chemistry Langyan S, Yadava P, Sharma S, Gupta NC, Bansal R, Yadav R, et al.
Sesame oil, despite being an under-utilized minor crop, is rich in nutrients such as lignans, tocopherols, phytosterols, natural antioxidants, and bioactive compounds. The review underscores its various health benefits, including anti-lipogenic, hypo-cholesterolemic, anti-degenerative, and neural health-promoting properties. The study emphasizes the need for more research to explore sesame oil's food and nutraceutical potential, positioning it as a valuable candidate for maintaining diversity in food oils and improving human health.
Theoretical Article Review Article Sesame OilNutritional and Therapeutic Potential of Sesame Seeds
2022 Apr 22 Journal of Food Quality Abbas S, Sharif MK, Sibt-e-Abbas M, Fikre Teferra T, Sultan MT, Anwar MJ
The study concludes that sesame seeds and oil have significant potential in the pharmaceuticals, nutraceuticals, and food industries, particularly in snack production.
Review Article Sesame seeds Nutrition SesameHypolipidemic effect of Sesame Seed Oil: A Review
2022 Apr 30 Pakistan BioMedical Journal Arshad M, Ashfaq M, Rizwan B, Zanib R, Fatima A, Pervaiz R, et al.
Sesame seed oil and its derivatives have shown to be highly effective in managing hyperlipidemia and dyslipidemia due to their lipid ameliorating and anti-oxidative effects.
Experimental Study Review Article Cholesterol Sesame Oil HypercholesterolemiaConsumption of sesame seeds and sesame products has favorable effects on blood glucose levels but not on insulin resistance: A systematic review and meta‐analysis of controlled clinical trials
2022 Jan 18 Phytotherapy Research Sohouli MH, Haghshenas N, Hernández‐Ruiz , Shidfar F
Systematic Review Meta-Analysis Blood Sugar SesameConsumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
Sesame Seed and Its Fractions for Improving Oxidative Stress in Adults: A Systematic Review and Meta-analysis of Controlled Clinical Trials
2019 Nov 06 Food Reviews International Moghtaderi F, Ramezani-Jolfaie N, Raeisi-Dehkordi H, Salehi-Abargouei A
Systematic Review Meta-Analysis Oxidative Stress AntioxidantSesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants.
Presentation Slides
Consumption of sesame seeds and its products positively influences human glucose metabolism, potentially making it a beneficial addition to glucose-lowering diets.
Sesame consumption significantly increases enzymatic (superoxide dismutase, glutathione peroxidase, catalase) and non-enzymatic (vitamin C, vitamin E, β-carotene, and glutathione) antioxidants.
Sesame oil intake was associated with reduced body weight and body mass index.
The biomarkers that were significantly different between black seeds and white sesame seeds are highly related to the functions recorded in traditional Chinese medicine.
Of the 7 clinical trials included, five evaluating individuals with hypertension observed a significant reduction in systolic and/or diastolic blood pressure. The two articles that evaluated individuals with dyslipidemia showed improvement in lipid profile.
The studies assessed showed that sesame could have a significant effect on oxidative stress and the antioxidant defense system, being considered a food with an important antioxidant function in the different populations studied.
These results suggest the possible antihypertensive effects of black sesame meal on improving antioxidant status and decreasing oxidant stress.
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